World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
78
Citations
23177
World Ranking
1272
National Ranking
110

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Bacteria
  • DNA

His primary areas of investigation include Microbiology, Salmonella typhi, Typhoid fever, Genetics and Salmonella. His Microbiology research focuses on Internal medicine and how it relates to Coinfection. His Salmonella typhi research is multidisciplinary, relying on both Veterinary medicine, Interquartile range and Incidence.

The Typhoid fever study combines topics in areas such as Antibacterial agent, Gastroenterology, Immunology, Chloramphenicol and Ofloxacin. The various areas that he examines in his Salmonella study include Genetic variation, Molecular evolution, Phylogenetic tree and Virulence. His Salmonella enterica study which covers Phylogenetics that intersects with Subspecies.

His most cited work include:

  • Performance comparison of benchtop high-throughput sequencing platforms (1067 citations)
  • Performance comparison of benchtop high-throughput sequencing platforms (1067 citations)
  • Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18 (1059 citations)

What are the main themes of his work throughout his whole career to date?

John Wain spends much of his time researching Microbiology, Salmonella typhi, Typhoid fever, Genetics and Salmonella. His study of Serotype is a part of Microbiology. His work investigates the relationship between Serotype and topics such as Salmonella enterica that intersect with problems in Enterobacteriaceae.

His Salmonella typhi research is multidisciplinary, incorporating elements of Chloramphenicol, Antibiotic resistance and Drug resistance. His Typhoid fever research includes elements of Ofloxacin, Internal medicine, Antibacterial agent and Immunology. His work deals with themes such as Veterinary medicine and Genomic island, which intersect with Salmonella.

He most often published in these fields:

  • Microbiology (58.70%)
  • Salmonella typhi (43.72%)
  • Typhoid fever (46.96%)

What were the highlights of his more recent work (between 2015-2021)?

  • Whole genome sequencing (12.15%)
  • Microbiology (58.70%)
  • Genetics (30.77%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Whole genome sequencing, Microbiology, Genetics, Genome and Gene. His research in Whole genome sequencing intersects with topics in Salmonella typhi, Salmonella enterica, Outbreak, Genomics and Computational biology. His Salmonella typhi study incorporates themes from Mutation, Wild type and Virology.

His studies in Microbiology integrate themes in fields like Genotype and Escherichia coli. His work carried out in the field of Genetics brings together such families of science as Gut flora and Serotype. His research investigates the link between Genome and topics such as DNA sequencing that cross with problems in Multiplex.

Between 2015 and 2021, his most popular works were:

  • Identification of bacterial pathogens and antimicrobial resistance directly from clinical urines by nanopore-based metagenomic sequencing (171 citations)
  • Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection. (99 citations)
  • Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection. (99 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Bacteria
  • DNA

His primary areas of study are Nanopore sequencing, Genetics, Metagenomics, Nanopore and Microbiology. His Genetics study frequently intersects with other fields, such as Gut flora. His Microbiology research incorporates themes from Multilocus sequence typing and Escherichia coli.

His biological study spans a wide range of topics, including Genomic island and Salmonella. His work on Salmonella enterica is typically connected to Context as part of general Salmonella study, connecting several disciplines of science. His Plasmid research includes themes of Salmonella typhi and Typhoid fever.

Best Publications

  • Performance comparison of benchtop high-throughput sequencing platforms

    Nicholas J Loman;Raju V Misra;Timothy J Dallman;Chrystala Constantinidou

  • Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18

    J. Parkhill;G. Dougan;K. D. James;N. R. Thomson

  • A study of typhoid fever in five asian countries: disease burden and implications for controls

    R Leon Ochiai;Camilo J Acosta;M Carolina Danovaro-Holliday;Dong Baiqing

  • Multilocus Sequence Typing as a Replacement for Serotyping in Salmonella enterica

    Mark Achtman;John Wain;John Wain;François Xavier Weill;Satheesh Nair;Satheesh Nair

  • Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants

    Gemma C. Langridge;Minh Duy Phan;Daniel J. Turner;Timothy T. Perkins

  • Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection.

    Themoula Charalampous;Gemma L Kay;Gemma L Kay;Hollian Richardson;Alp Aydin

  • High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi

    Kathryn E. Holt;Julian Parkhill;Camila J. Mazzoni;Philippe Roumagnac

  • MinION nanopore sequencing identifies the position and structure of a bacterial antibiotic resistance island.

    Philip M Ashton;Satheesh Nair;Tim J Dallman;Salvatore Rubino

  • Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa

    Chinyere K. Okoro;Robert A. Kingsley;Thomas Richard Connor;Simon R. Harris

  • Salmonella typhi, the causative agent of typhoid fever, is approximately 50,000 years old.

    Claire Kidgell;Ulrike Reichard;John Wain;Bodo Linz

  • Quinolone-resistant Salmonella typhi in Viet Nam: molecular basis of resistance and clinical response to treatment

    John Wain;Nguyen T. T. Hoa;Nguyen T. Chinh;Ha Vinh

  • Quantitation of Bacteria in Blood of Typhoid Fever Patients and Relationship between Counts and Clinical Features, Transmissibility, and Antibiotic Resistance

    J Wain;T S Diep;V A Ho;A M Walsh;A M Walsh

  • Identification of bacterial pathogens and antimicrobial resistance directly from clinical urines by nanopore-based metagenomic sequencing

    K. Schmidt;S. Mwaigwisya;L. C. Crossman;M. Doumith

  • International Spread of an Epidemic Population of Salmonella enterica Serotype Kentucky ST198 Resistant to Ciprofloxacin

    Simon Le Hello;Rene S. Hendriksen;Benoit Doublet;Ian Fisher

  • Antimicrobial Drug Resistance of Salmonella enterica Serovar Typhi in Asia and Molecular Mechanism of Reduced Susceptibility to the Fluoroquinolones

    Tran Thuy Chau;James Ian Campbell;James Ian Campbell;Claudia M. Galindo;Nguyen Van Minh Hoang

  • Typhoid fever: pathogenesis and disease.

    Deborah House;Anne Bishop;Christopher Parry;Gordon Dougan

  • Quantitation of Bacteria in Bone Marrow from Patients with Typhoid Fever: Relationship between Counts and Clinical Features

    John Wain;John Wain;Phan Van Be Bay;H. A. Vinh;Nguyen M. Duong

  • Salmonella Paratyphi A Rates, Asia

    R. Leon Ochiai;XuanYi Wang;Lorenz von Seidlein;Jin Yang

  • An H-NS-like stealth protein aids horizontal DNA transmission in bacteria.

    Marie Doyle;Maria Fookes;Al Ivens;Michael W. Mangan

  • Pseudogene accumulation in the evolutionary histories of Salmonella enterica serovars Paratyphi A and Typhi.

    Kathryn E Holt;Nicholas R Thomson;John Wain;Gemma C Langridge

  • Value of a Single-Tube Widal Test in Diagnosis of Typhoid Fever in Vietnam

    Christopher M. Parry;Christopher M. Parry;Nguyen Thi Tuyet Hoa;To Song Diep;John Wain;John Wain

Frequent Co-Authors

Christopher M. Parry
Christopher M. Parry Liverpool School of Tropical Medicine
Nicholas J. White
Nicholas J. White Mahidol University
Jeremy Farrar
Jeremy Farrar World Health Organization
Gordon Dougan
Gordon Dougan University of Cambridge
Tran Tinh Hien
Tran Tinh Hien University of Oxford
Julian Parkhill
Julian Parkhill University of Cambridge
Stephen Baker
Stephen Baker Agency for Science, Technology and Research
Nicholas R. Thomson
Nicholas R. Thomson Wellcome Sanger Institute
Nicholas P. J. Day
Nicholas P. J. Day University of Oxford
David M. Livermore
David M. Livermore University of East Anglia

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