World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
91
Citations
42680
World Ranking
637
National Ranking
64

Genetics

D-Index
85
Citations
42052
World Ranking
1282
National Ranking
168

Overview

Kathryn E. Holt is affiliated with the London School of Hygiene & Tropical Medicine in the United Kingdom. Their research primarily spans biochemistry, genetics, and molecular biology, with significant contributions focused on molecular biology, molecular medicine, endocrinology, ecology, and food science.

Their published work covers a range of topics including antibiotic resistance in bacteria, genomics and phylogenetic studies, Salmonella and Campylobacter epidemiology, bacteriophages and microbial interactions, bacterial identification and susceptibility testing, Vibrio bacteria research studies, and Enterobacteriaceae and Cronobacter research.

Frequent co-authors collaborating with Kathryn E. Holt include:

  • Kelly L. Wyres
  • Louise M. Judd
  • Ryan R. Wick
  • Jane Hawkey
  • Margaret M. C. Lam

Most of their publications appear in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Microbial Genomics
  • Nature Communications
  • Genome Medicine
  • The Lancet Microbe

Recent papers by Kathryn E. Holt include:

  • Population genomics of Klebsiella pneumoniae, 2020, Nature Reviews Microbiology
  • A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex, 2021, Nature Communications
  • Polypolish: Short-read polishing of long-read bacterial genome assemblies, 2022, PLoS Computational Biology
  • Trycycler: consensus long-read assemblies for bacterial genomes, 2021, Genome Biology
  • Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia, 2020, Genome Medicine

Best Publications

  • Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads.

    Ryan R. Wick;Louise M. Judd;Claire L. Gorrie;Kathryn E. Holt

  • Performance of neural network basecalling tools for Oxford Nanopore sequencing.

    Ryan R. Wick;Louise M. Judd;Kathryn E. Holt;Kathryn E. Holt

  • Bandage: interactive visualization of de novo genome assemblies

    Ryan R. Wick;Mark B. Schultz;Justin Zobel;Kathryn E. Holt

  • Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health

    Kathryn E. Holt;Heiman Wertheim;Ruth N. Zadoks;Stephen Baker

  • Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans

    Iñaki Comas;Mireia Coscolla;Mireia Coscolla;Tao Luo;Sonia Borrell;Sonia Borrell

  • SRST2: Rapid genomic surveillance for public health and hospital microbiology labs

    Michael Inouye;Harriet Dashnow;Harriet Dashnow;Lesley Ann Raven;Mark B. Schultz

  • Completing bacterial genome assemblies with multiplex MinION sequencing

    Ryan R. Wick;Louise M. Judd;Claire L. Gorrie;Kathryn E. Holt

  • The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development

    Shu Mei Teo;Danny Mok;Kym Pham;Merci Kusel

  • Population genomics of Klebsiella pneumoniae.

    Kelly L Wyres;Margaret M C Lam;Kathryn E Holt;Kathryn E Holt

  • A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex.

    Margaret M. C. Lam;Ryan R. Wick;Stephen C. Watts;Louise T. Cerdeira

  • Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype

    Robert A. Kingsley;Chisomo L. Msefula;Nicholas R. Thomson;Samuel Kariuki;Samuel Kariuki

  • Klebsiella pneumoniae as a key trafficker of drug resistance genes from environmental to clinically important bacteria

    Kelly L Wyres;Kathryn E Holt

  • High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi

    Kathryn E. Holt;Julian Parkhill;Camila J. Mazzoni;Philippe Roumagnac

  • Gastrointestinal Carriage Is a Major Reservoir of Klebsiella pneumoniae Infection in Intensive Care Patients.

    Claire L. Gorrie;Mirjana Mirčeta;Ryan R. Wick;David J. Edwards

  • Identification of Klebsiella capsule synthesis loci from whole genome data.

    Kelly L. Wyres;Ryan R. Wick;Claire Gorrie;Adam Jenney

  • Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

    Vanessa K. Wong;Vanessa K. Wong;Stephen Baker;Stephen Baker;Stephen Baker;Derek J. Pickard;Julian Parkhill

  • Trycycler: consensus long-read assemblies for bacterial genomes

    Ryan R. Wick;Louise M. Judd;Louise T. Cerdeira;Jane Hawkey

  • The DNA sequence and biological annotation of human chromosome 1

    S. G. Gregory;S. G. Gregory;K. F. Barlow;K. E. McLay;R. Kaul

  • Evolutionary dynamics of Clostridium difficile over short and long time scales

    Miao He;Mohammed Sebaihia;Trevor D. Lawley;Richard A. Stabler

  • Genomic insights into the emergence and spread of antimicrobial-resistant bacterial pathogens.

    Stephen Baker;Stephen Baker;Nicholas Thomson;Nicholas Thomson;François Xavier Weill;Kathryn E. Holt;Kathryn E. Holt

  • An immunoepidemiological approach to asthma: identification of in-vitro T-cell response patterns associated with different wheezing phenotypes in children.

    T Heaton;J Rowe;S Turner;R C Aalberse

Frequent Co-Authors

Ryan R. Wick
Ryan R. Wick Peter Doherty Institute
Stephen Baker
Stephen Baker Agency for Science, Technology and Research
Gordon Dougan
Gordon Dougan University of Cambridge
Nicholas R. Thomson
Nicholas R. Thomson Wellcome Sanger Institute
Michael Inouye
Michael Inouye Baker IDI Heart and Diabetes Institute
Ruth M. Hall
Ruth M. Hall University of Sydney
Patrick G. Holt
Patrick G. Holt University of Western Australia
François-Xavier Weill
François-Xavier Weill Institut Pasteur
Julian Parkhill
Julian Parkhill University of Cambridge
Guy E. Thwaites
Guy E. Thwaites University of Oxford

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