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Immunology
Australia
2026
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Medicine
Australia
2023

D-Index & Metrics

Immunology

D-Index
125
Citations
57371
World Ranking
285
National Ranking
6

Medicine

D-Index
125
Citations
57637
World Ranking
3098
National Ranking
86

Research.com Recognitions

  • 2026 - Research.com Immunology in Australia Leader Award
  • 2025 - Research.com Immunology in Australia Leader Award
  • 2023 - Research.com Immunology in Australia Leader Award
  • 2023 - Research.com Medicine in Australia Leader Award
  • 2022 - Research.com Immunology in Australia Leader Award
  • 2001 - Fellow of the Australian Academy of Science

Overview

Patrick G. Holt is affiliated with the University of Western Australia in Australia. Their research spans multiple domains primarily within medicine and immunology and microbiology, contributing significantly to these disciplines through a focused body of work.

The scientist's main fields of study are:

  • Medicine
  • Immunology and Microbiology

Within these broader disciplines, they have concentrated on several subfields, including:

  • Epidemiology
  • Immunology
  • Pulmonary and Respiratory Medicine
  • Emergency Medical Services
  • Physiology

Patrick G. Holt's research covers key topics such as:

  • Respiratory viral infections research
  • Pediatric health and respiratory diseases
  • Asthma and respiratory diseases
  • Neonatal Respiratory Health Research
  • Bacterial Infections and Vaccines
  • IL-33, ST2, and ILC Pathways
  • Immune Cell Function and Interaction

Their recent publications include the following papers with corresponding years and venues:

  • "Assessing the strength of evidence for a causal effect of respiratory syncytial virus lower respiratory tract infections on subsequent wheezing illness: a systematic review and meta-analysis" (2020), The Lancet Respiratory Medicine
  • "Developmental patterns in the nasopharyngeal microbiome during infancy are associated with asthma risk" (2020), Journal of Allergy and Clinical Immunology
  • "Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infection" (2023), Immunity
  • "Protection against severe infant lower respiratory tract infections by immune training: Mechanistic studies" (2022), Journal of Allergy and Clinical Immunology
  • "Neonatal genetics of gene expression reveal potential origins of autoimmune and allergic disease risk" (2020), Nature Communications

Frequent co-authors collaborating with Patrick G. Holt include:

  • Deborah H. Strickland
  • Peter D. Sly
  • Anthony Bosco
  • Michael Serralha
  • James F. Read

The scientist's work has appeared predominantly in several publication venues, demonstrating sustained contributions to specific journals:

  • Journal of Allergy and Clinical Immunology (7 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (7 publications)
  • Frontiers in Immunology (4 publications)
  • Nature Communications (2 publications)
  • American Journal of Respiratory and Critical Care Medicine (2 publications)

Among their recognitions, Patrick G. Holt was awarded the status of Fellow of the Australian Academy of Science in 2001.

Best Publications

  • Development of allergen-specific T-cell memory in atopic and normal children

    S. L. Prescott;C. Macaubas;T. Smallacombe;B. J. Holt

  • After asthma: redefining airways diseases

    Ian D Pavord;Richard Beasley;Alvar Agusti;Gary P Anderson

  • A Polymorphism* in the 5 ′ Flanking Region of the CD14 Gene Is Associated with Circulating Soluble CD14 Levels and with Total Serum Immunoglobulin E

    Mauro Baldini;I. Carla Lohman;Marilyn Halonen;Robert P. Erickson

  • The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development

    Shu Mei Teo;Danny Mok;Kym Pham;Merci Kusel

  • Transplacental Priming of the Human Immune System to Environmental Allergens: Universal Skewing of Initial T Cell Responses Toward the Th2 Cytokine Profile

    Susan L. Prescott;Claudia Macaubas;Barbara J. Holt;Troy B. Smallacombe

  • Early-life respiratory viral infections, atopic sensitization, and risk of subsequent development of persistent asthma

    Merci M.H. Kusel;Nicholas H. de Klerk;Tatiana Kebadze;Vaike Vohma

  • Association Between Breast Feeding and Asthma in 6 Year Old Children: Findings of a Prospective Birth Cohort Study

    W. H. Oddy;P. G. Holt;P. D. Sly;A. W. Read

  • The role of allergy in the development of asthma

    P. G. Holt;C. Macaubas;C. Macaubas;P. A. Stumbles;P. A. Stumbles;P. D. Sly;P. D. Sly

  • Downregulation of the Antigen Presenting Cell Function(s) of Pulmonary Dendritic Cells In Vivo by Resident Alveolar Macrophages

    Patrick G. Holt;Jane Oliver;Natalie Bilyk;Christine McMenamin

  • Fish oil supplementation in pregnancy modifies neonatal allergen-specific immune responses and clinical outcomes in infants at high risk of atopy: A randomized, controlled trial

    Janet A Dunstan;Trevor A Mori;Anne Barden;Lawrence J Beilin

  • Allergic respiratory disease: strategic targets for primary prevention during childhood.

    P G Holt;P D Sly

  • A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells

    J.D. Sedgwick;P.G. Holt

  • Regulation of immunological homeostasis in the respiratory tract

    Patrick G. Holt;Deborah H. Strickland;Matthew E. Wikström;Frode L. Jahnsen

  • Macrophage-Derived Nitric Oxide Regulates T Cell Activation via Reversible Disruption of the Jak3/STAT5 Signaling Pathway

    Roland M. Bingisser;Peta A. Tilbrook;Patrick G. Holt;Ursula R. Kees

  • The development of the immune system during pregnancy and early life.

    P. G. Holt;C. A. Jones

  • Phenotypic, Functional, and Plasticity Features of Classical and Alternatively Activated Human Macrophages

    Abdullah A. Tarique;Jayden Logan;Emma Thomas;Patrick G. Holt

  • Role of microbial burden in aetiology of allergy and asthma.

    Fernande D Martinez;Patrick G Holt

  • Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity.

    Philip A. Stumbles;Jennifer A. Thomas;Carolyn L. Pimm;Peter T. Lee

  • Regulation of IgE responses to inhaled antigen in mice by antigen-specific gamma delta T cells

    Christine McMenamin;Carolyn Pimm;Michelle McKersey;Patrick G. Holt

  • Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces.

    A S McWilliam;D Nelson;J A Thomas;P G Holt

  • Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

    Florence Demenais;Florence Demenais;Patricia Margaritte-Jeannin;Patricia Margaritte-Jeannin;Kathleen C. Barnes;William O.C. Cookson

  • Immune and inflammatory function in cigarette smokers.

    P G Holt

Frequent Co-Authors

Peter D. Sly
Peter D. Sly University of Queensland
Susan L. Prescott
Susan L. Prescott Telethon Kids Institute
John W. Upham
John W. Upham University of Queensland
Wayne R. Thomas
Wayne R. Thomas Telethon Kids Institute
Kathryn E. Holt
Kathryn E. Holt London School of Hygiene & Tropical Medicine
Adnan Custovic
Adnan Custovic Imperial College London
Michael Inouye
Michael Inouye Baker IDI Heart and Diabetes Institute
Peter Richmond
Peter Richmond University of Western Australia
Angela Simpson
Angela Simpson University of Manchester
Nicholas de Klerk
Nicholas de Klerk University of Western Australia

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