World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
65
Citations
11964
World Ranking
2880
National Ranking
116

Overview

John W. Upham is affiliated with the University of Queensland in Australia and is an active researcher in the field of medicine, with a focus on pulmonary and respiratory medicine. Their work spans several subfields including physiology, epidemiology, immunology, and surgery.

The primary research topics covered in their publications include:

  • Asthma and respiratory diseases
  • Respiratory and cough-related research
  • IL-33, ST2, and ILC pathways
  • Inhalation and respiratory drug delivery
  • Respiratory viral infections research
  • Chronic obstructive pulmonary disease (COPD) research
  • Delphi technique in research

Upham has contributed to numerous papers, with recent examples including:

  • "Mepolizumab effectiveness and identification of super-responders in severe asthma," 2020, European Respiratory Journal
  • "Defining a Severe Asthma Super-Responder: Findings from a Delphi Process," 2021, The Journal of Allergy and Clinical Immunology In Practice
  • "Respiratory Syncytial Virus Infection Promotes Necroptosis and HMGB1 Release by Airway Epithelial Cells," 2020, American Journal of Respiratory and Critical Care Medicine
  • "Oral corticosteroids stewardship for asthma in adults and adolescents: A position paper from the Thoracic Society of Australia and New Zealand," 2021, Respirology
  • "Exploring Definitions and Predictors of Severe Asthma Clinical Remission after Biologic Treatment in Adults," 2024, American Journal of Respiratory and Critical Care Medicine

Frequent co-authors of Upham include:

  • Peter G. Gibson
  • Mark Hew (21 publications)
  • Matthew Peters (17 publications)
  • Vanessa M. McDonald (16 publications)
  • Christine Jenkins (13 publications)

Their research has been published most frequently in the following venues:

  • The Journal of Allergy and Clinical Immunology In Practice (9 publications)
  • European Respiratory Journal (5 publications)
  • Respirology (5 publications)
  • American Journal of Respiratory and Critical Care Medicine (3 publications)
  • Allergy (3 publications)

Upham's research contributes to advancing knowledge in asthma, respiratory diseases, and related immunological pathways, as well as employing methodologies such as the Delphi technique to refine clinical definitions and treatment strategies.

Best Publications

  • Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial

    Peter G Gibson;Peter G Gibson;Ian A Yang;John W Upham;John W Upham;Paul N Reynolds;Paul N Reynolds

  • Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology

    Steven L Taylor;Lex E X Leong;Jocelyn M Choo;Steven L Wesselingh

  • Rapid dendritic cell recruitment to the bronchial mucosa of patients with atopic asthma in response to local allergen challenge

    F.L. Jahnsen;E.D. Moloney;T. Hogan;J.W. Upham

  • Contemporaneous maturation of immunologic and respiratory functions during early childhood: implications for development of asthma prevention strategies.

    Patrick G. Holt;John W. Upham;Peter D. Sly

  • Development of interleukin-12-producing capacity throughout childhood.

    John W. Upham;Peter T. Lee;Barbara J. Holt;Tricia Heaton

  • Full blood count parameters for the detection of asthma inflammatory phenotypes

    X.Y. Zhang;J.L. Simpson;H. Powell;I.A. Yang

  • Airway dysbiosis: Haemophilus influenzae and Tropheryma in poorly controlled asthma

    Jodie L. Simpson;Joshua Daly;Katherine J. Baines;Ian A. Yang

  • TLR4 polymorphisms mediate impaired responses to respiratory syncytial virus and lipopolysaccharide.

    Meri K. Tulic;Robert J. Hurrelbrink;Cecilia M. Prêle;Ingrid A. Laing

  • Protracted bacterial bronchitis: The last decade and the road ahead.

    Anne B. Chang;Anne B. Chang;John W. Upham;I. Brent Masters;I. Brent Masters;Gregory R. Redding

  • Mepolizumab effectiveness and identification of super-responders in severe asthma

    Erin S. Harvey;Erin S. Harvey;David Langton;David Langton;Constance Katelaris;Constance Katelaris;Sean Stevens

  • Functional Maturation of CD4+CD25+CTLA4+CD45RA+ T Regulatory Cells in Human Neonatal T Cell Responses to Environmental Antigens/Allergens

    Catherine A. Thornton;John W. Upham;Matthew E. Wikström;Barbara J. Holt

  • Treatable traits can be identified in a severe asthma registry and predict future exacerbations

    Vanessa M McDonald;Sarah A Hiles;Krystelle Godbout;Erin S Harvey;Erin S Harvey

  • Long-Term Azithromycin Reduces Haemophilus influenzae and Increases Antibiotic Resistance in Severe Asthma.

    Steven L. Taylor;Lex E. X. Leong;Fredrick M. Mobegi;Jocelyn M. Choo

  • Protracted Bacterial Bronchitis in Children: Natural History and Risk Factors for Bronchiectasis

    Danielle F. Wurzel;Julie M. Marchant;Stephanie T. Yerkovich;John W. Upham

  • Reduced soluble receptor for advanced glycation end-products in COPD

    D.J. Smith;S.T. Yerkovich;M.A. Towers;M.L. Carroll

  • Postnatal development of monocyte cytokine responses to bacterial lipopolysaccharide.

    Stephanie T Yerkovich;Matthew E Wikström;Devinda Suriyaarachchi;Susan L Prescott

  • Impaired macrophage phagocytosis in non-eosinophilic asthma.

    J. L. Simpson;P. G. Gibson;I. A. Yang;J. Upham

  • Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma

    Severine Navarro;Darren A. Pickering;Ivana B. Ferreira;Linda Jones

  • Defining a Severe Asthma Super-Responder: Findings from a Delphi Process.

    John W. Upham;John W. Upham;Chantal Le Lievre;David J. Jackson;Matthew Masoli

  • Inhalant allergen‐specific T‐cell reactivity is detectable in close to 100% of atopic and normal individuals: covert responses are unmasked by serum‐free medium

    J. W. Upham;J. W. Upham;B. J. Holt;M. J. Baron-Hay;A. Yabuhara

  • T‐cell “priming” against environmental allergens in human neonates: sequential deletion of food antigen reactivity during infancy with concomitant expansion of responses to ubiquitous inhalant allergens

    P.G. Holt;P. O'Keeffe;B.J. Holt;J.W. Upham

Frequent Co-Authors

Peter G. Gibson
Peter G. Gibson University of Newcastle Australia
Anne B. Chang
Anne B. Chang Boston Children's Hospital
Sandra Hodge
Sandra Hodge University of Adelaide
Alan James
Alan James Sir Charles Gairdner Hospital
Jodie L. Simpson
Jodie L. Simpson University of Newcastle Australia
Paul N. Reynolds
Paul N. Reynolds University of Adelaide
Patrick G. Holt
Patrick G. Holt University of Western Australia
Guy B. Marks
Guy B. Marks University of New South Wales
Simon Phipps
Simon Phipps University of Queensland
Peter A. B. Wark
Peter A. B. Wark University of Newcastle Australia

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students studying Immunology in the USA, several related online degrees offer viable career pathways, especially in healthcare and research fields. Nursing, for example, provides specialized roles that align well with immunological expertise.

Those interested in mental health can explore the cheapest online pmhnp programs, which offer affordable routes into psychiatric nursing while leveraging a strong background in immunology and neuroscience.

Furthermore, advancing your nursing qualifications through accelerated options is achievable via accelerated fnp programs. These programs prepare you quickly for family nurse practitioner roles, often integrating immunological knowledge in patient care.

Transitioning to specialized care units is also possible by obtaining an acute care nurse practitioner certification, which equips nurses to handle critical patients, where immunology often plays a key role in treatment decisions.

Salary considerations are vital when choosing a career. The dnp salary by specialty provides essential insights into how different nurse practitioner specialties, including those related to immunology, are compensated across the USA.

Best Scientists Citing John W. Upham

Trending Scientists

Recently Published Articles