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Anne Lombès

Anne Lombès

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
17352
World Ranking
6670
National Ranking
200

Overview

Anne Lombès is a researcher affiliated with Inserm in France, specializing in fields related to biochemistry, genetics, and molecular biology, with additional focus on medicine. Their work spans several subfields including molecular biology, cardiology and cardiovascular medicine, immunology, clinical biochemistry, and cancer research.

Lombès's main topics of research encompass mitochondrial function and pathology, redox biology and oxidative stress, connexins and lens biology, advanced glycation end products research, S100 proteins and annexins, immune cells in cancer, and immune response and inflammation.

Recent publications by Lombès reflect a focus on cellular and molecular mechanisms, particularly related to mitochondrial dynamics and oxidative stress. These works include:

  • Use of H2O2 to Cause Oxidative Stress, the Catalase Issue (2020, International Journal of Molecular Sciences)
  • S100A8-mediated metabolic adaptation controls HIV-1 persistence in macrophages in vivo (2022, Nature Communications)
  • Hypoxia Promotes Mitochondrial Complex I Abundance via HIF-1α in Complex III and Complex IV Deficient Cells (2020, Cells)
  • Homoplasmic deleterious MT-ATP6/8 mutations in adult patients (2020, Mitochondrion)
  • Methylene blue induced O2 consumption is not dependent on mitochondrial oxidative phosphorylation: Implications for salvage pathways during acute mitochondrial poisoning (2022, Respiratory Physiology & Neurobiology)

Lombès frequently collaborates with several researchers including Céline Ransy, Frédéric Bouillaud, Benoît Rucheton, Sandrine Filaut, and Clément Vaz. These partnerships have contributed to multiple publications across various specialized journals.

Their contributions have appeared in a range of scientific venues including the International Journal of Molecular Sciences, Nature Communications, Cells, Mitochondrion, and Respiratory Physiology & Neurobiology.

Best Publications

  • Mitochondrial DNA Deletions in Progressive External Ophthalmoplegia and Kearns-Sayre Syndrome

    Carlos T. Moraes;Salvatore Dimauro;Massimo Zeviani;Anne Lombes

  • Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins.

    Frédéric Legros;Anne Lombès;Paule Frachon;Manuel Rojo

  • Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo

    Manuel Rojo;Frédéric Legros;Danielle Chateau;Anne Lombès

  • Organization and dynamics of human mitochondrial DNA

    Frédéric Legros;Florence Malka;Paule Frachon;Anne Lombès

  • Genetic diagnosis of Mendelian disorders via RNA sequencing

    Laura S. Kremer;Daniel M. Bader;Daniel M. Bader;Christian Mertes;Robert Kopajtich

  • Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): Clinical, biochemical, and genetic features of an autosomal recessive mitochondrial disorder

    Michio Hirano;G. Silvestri;D. M. Blake;A. Lombes

  • CABC1 Gene Mutations Cause Ubiquinone Deficiency with Cerebellar Ataxia and Seizures

    Julie Mollet;Agnès Delahodde;Valérie Serre;Dominique Chretien

  • A mutant mitochondrial respiratory chain assembly protein causes complex III deficiency in patients with tubulopathy, encephalopathy and liver failure

    Pascale De Lonlay;Isabelle Valnot;Antoni Barrientos;Marina Gorbatyuk

  • Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease.

    Günter U. Höglinger;Géraldine Carrard;Patrick P. Michel;Fadia Medja

  • Zidovudine-induced mitochondrial disorder with massive liver steatosis, myopathy, lactic acidosis, and mitochondrial DNA depletion

    Patrick Chariot;Irène Drogou;Isabelle de Lacroix-Szmania;Marie-Christine Eliezer-Vanerot

  • Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: possible relevance for atypical parkinsonism in Guadeloupe.

    Pierre Champy;Günter U. Höglinger;Jean Feger;Christophe Gleye

  • Risk of developing a mitochondrial DNA deletion disorder

    Patrick F Chinnery;Salvatore DiMauro;Sara Shanske;Eric A Schon

  • Separate fusion of outer and inner mitochondrial membranes.

    Florence Malka;Olwenn Guillery;Carmen Cifuentes-Diaz;Emmanuelle Guillou

  • Development and implementation of standardized respiratory chain spectrophotometric assays for clinical diagnosis.

    Fadia Medja;S. Allouche;Paule Frachon;Claude Jardel;Claude Jardel

  • Ageing muscle: clonal expansions of mitochondrial DNA point mutations and deletions cause focal impairment of mitochondrial function.

    Guillemette Fayet;Monica Jansson;Damien Sternberg;Ali Reza Moslemi

  • Altered fat differentiation and adipocytokine expression are inter-related and linked to morphological changes and insulin resistance in HIV-1-infected lipodystrophic patients.

    Véronique Jan;Pascale Cervera;Mustapha Maachi;Marielle Baudrimont

  • The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy

    Giinter U. Höglinger;Annie Lannuzel;Myriam Escobar Khondiker;Myriam Escobar Khondiker;Patrick P. Michel

  • Use of H2O2 to Cause Oxidative Stress, the Catalase Issue.

    Céline Ransy;Clément Vaz;Anne Lombès;Frédéric Bouillaud

  • The Mitochondrial Complex I Inhibitor Annonacin Is Toxic to Mesencephalic Dopaminergic Neurons by Impairment of Energy Metabolism

    A Lannuzel;P.P Michel;G.U Höglinger;P Champy;P Champy

  • Metalloprotease-mediated OPA1 processing is modulated by the mitochondrial membrane potential

    Olwenn Guillery;Florence Malka;Florence Malka;Thomas Landes;Emmanuelle Guillou

Frequent Co-Authors

Bruno Eymard
Bruno Eymard Université Paris Cité
Salvatore DiMauro
Salvatore DiMauro Columbia University
Eduardo Bonilla
Eduardo Bonilla Columbia University
Frédéric Bouillaud
Frédéric Bouillaud Institut Cochin
Massimo Zeviani
Massimo Zeviani University of Padua
Eric A. Schon
Eric A. Schon Columbia University Medical Center
Arnold Munnich
Arnold Munnich Necker-Enfants Malades Hospital
Jean-Paul Bonnefont
Jean-Paul Bonnefont Necker-Enfants Malades Hospital
Carlos T. Moraes
Carlos T. Moraes University of Miami
Michel Fardeau
Michel Fardeau Grenoble Alpes University

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