Her scientific interests lie mostly in Mitochondrial DNA, Mitochondrion, Endocrinology, Internal medicine and Cell biology. Her Mitochondrial DNA research entails a greater understanding of Genetics. Her Mitochondrion research incorporates themes from Proteasome, Adenosine triphosphate and Creatine kinase.
Her Adiponectin, Adipocyte and Glucagon study in the realm of Internal medicine interacts with subjects such as Lipoatrophy and Ketogenesis. Mitochondrial fission is closely connected to mitochondrial fusion in her research, which is encompassed under the umbrella topic of Cell biology. Her research in Multiple mitochondrial DNA deletions focuses on subjects like Leukodystrophy, which are connected to Respiratory chain.
Her primary areas of investigation include Mitochondrial DNA, Internal medicine, Molecular biology, Mitochondrion and Genetics. Her Mitochondrial DNA study combines topics in areas such as Mutation and Point mutation. She interconnects Gastroenterology, Endocrinology, Surgery and Cardiology in the investigation of issues within Internal medicine.
Her Molecular biology research includes elements of Multiple mitochondrial DNA deletions, Cytochrome b, Gene, Cytochrome c oxidase and Respiratory chain. In her study, Glycolysis is inextricably linked to Oxidative phosphorylation, which falls within the broad field of Mitochondrion. In general Cell biology study, her work on ATP–ADP translocase, Mitochondrial membrane transport protein and Inner mitochondrial membrane often relates to the realm of Progenitor cell, thereby connecting several areas of interest.
Her primary areas of study are Cell biology, Mitochondrial DNA, Mitochondrial disease, Internal medicine and Mitochondrion. Her Cell biology study integrates concerns from other disciplines, such as Glycolysis, Cell, Oxidative phosphorylation and Cell culture. Anne Lombès usually deals with Mitochondrial DNA and limits it to topics linked to Mutation and Phenotype.
Her studies examine the connections between Mitochondrial disease and genetics, as well as such issues in Exercise intolerance, with regards to Metabolic myopathy, Gene mutation, Masseter muscle and Endocrinology. Her study looks at the relationship between Internal medicine and topics such as Respiratory chain, which overlap with Muscle biopsy, Cristae formation, Mitochondrial Encephalomyopathies, Cytochrome c oxidase and MICOS complex. Her Mitochondrion study combines topics from a wide range of disciplines, such as Molecular biology and Protein subunit.
Her main research concerns Cell biology, Mitochondrion, Mitochondrial disease, Molecular biology and Mitochondrial DNA. Her research in Cell biology intersects with topics in Cell culture, Cell and Cell growth. Her study on Mitochondrial disease is covered under Genetics.
Her research integrates issues of Mutation, Heteroplasmy, Kearns–Sayre syndrome and Proteases in her study of Molecular biology. The concepts of her Mutation study are interwoven with issues in Phenotype, RNA and Induced pluripotent stem cell. Her studies deal with areas such as HeLa, Small hairpin RNA and Transfection as well as Mitochondrial DNA.
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Mitochondrial DNA Deletions in Progressive External Ophthalmoplegia and Kearns-Sayre Syndrome
Carlos T. Moraes;Salvatore Dimauro;Massimo Zeviani;Anne Lombes.
The New England Journal of Medicine (1989)
Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins.
Frédéric Legros;Anne Lombès;Paule Frachon;Manuel Rojo.
Molecular Biology of the Cell (2002)
Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo
Manuel Rojo;Frédéric Legros;Danielle Chateau;Anne Lombès.
Journal of Cell Science (2002)
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): Clinical, biochemical, and genetic features of an autosomal recessive mitochondrial disorder
Michio Hirano;G. Silvestri;D. M. Blake;A. Lombes.
Neurology (1994)
Organization and dynamics of human mitochondrial DNA
Frédéric Legros;Florence Malka;Paule Frachon;Anne Lombès.
Journal of Cell Science (2004)
CABC1 Gene Mutations Cause Ubiquinone Deficiency with Cerebellar Ataxia and Seizures
Julie Mollet;Agnès Delahodde;Valérie Serre;Dominique Chretien.
American Journal of Human Genetics (2008)
Zidovudine-induced mitochondrial disorder with massive liver steatosis, myopathy, lactic acidosis, and mitochondrial DNA depletion
Patrick Chariot;Irène Drogou;Isabelle de Lacroix-Szmania;Marie-Christine Eliezer-Vanerot.
Journal of Hepatology (1999)
A mutant mitochondrial respiratory chain assembly protein causes complex III deficiency in patients with tubulopathy, encephalopathy and liver failure
Pascale De Lonlay;Isabelle Valnot;Antoni Barrientos;Marina Gorbatyuk.
Nature Genetics (2001)
Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease.
Günter U. Höglinger;Géraldine Carrard;Patrick P. Michel;Fadia Medja.
Journal of Neurochemistry (2003)
Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: possible relevance for atypical parkinsonism in Guadeloupe.
Pierre Champy;Günter U. Höglinger;Jean Feger;Christophe Gleye.
Journal of Neurochemistry (2003)
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