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Immunology

D-Index
66
Citations
12919
World Ranking
2793
National Ranking
248

Overview

Ian Sabroe is affiliated with the University of Sheffield in the United Kingdom. Their research primarily spans the field of Medicine, with a focused interest in Pulmonary and Respiratory Medicine, Cardiology and Cardiovascular Medicine, Immunology, Infectious Diseases, and Atomic and Molecular Physics, and Optics.

The scientist's work covers diverse topics, including:

  • Pulmonary Hypertension Research and Treatments
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • COVID-19 Clinical Research Studies
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Cardiovascular Function and Risk Factors
  • Inflammasome and immune disorders
  • Vascular Anomalies and Treatments

Frequent publication venues include:

  • European Respiratory Journal (3 publications)
  • ERJ Open Research (3 publications)
  • Clinical & Experimental Immunology (3 publications)
  • Nature Communications (2 publications)
  • Pulmonary Circulation (2 publications)

Among recent papers, notable titles include:

  • "A Bittersweet Response to Infection in Diabetes; Targeting Neutrophils to Modify Inflammation and Improve Host Immunity," 2021, Frontiers in Immunology
  • "Mild parenchymal lung disease and/or low diffusion capacity impacts survival and treatment response in patients diagnosed with idiopathic pulmonary arterial hypertension," 2020, European Respiratory Journal
  • "Diagnostic accuracy of CT pulmonary angiography in suspected pulmonary hypertension," 2020, European Radiology
  • "Lung MRI with hyperpolarised gases: current & future clinical perspectives," 2021, British Journal of Radiology
  • "EmPHasis-10 health-related quality of life score predicts outcomes in patients with idiopathic and connective tissue disease-associated pulmonary arterial hypertension: results from a UK multicentre study," 2020, European Respiratory Journal

The scientist has collaborated frequently with several coauthors, including:

  • David G. Kiely (12 collaborations)
  • Robin Condliffe (12 collaborations)
  • A. A. Roger Thompson (10 collaborations)
  • Athanasios Charalampopoulos (9 collaborations)
  • Charlie Elliot (8 collaborations)

Best Publications

  • Toll-Like Receptor (TLR)2 and TLR4 in Human Peripheral Blood Granulocytes: A Critical Role for Monocytes in Leukocyte Lipopolysaccharide Responses

    Ian Sabroe;Elizabeth C. Jones;Lynne R. Usher;Moira K. B. Whyte

  • Selective Roles for Toll-Like Receptor (TLR)2 and TLR4 in the Regulation of Neutrophil Activation and Life Span

    Ian Sabroe;Lynne R. Prince;Elizabeth C. Jones;Malcolm J. Horsburgh

  • Eotaxin (CCL11) and Eotaxin-2 (CCL24) Induce Recruitment of Eosinophils, Basophils, Neutrophils, and Macrophages As Well As Features of Early- and Late-Phase Allergic Reactions Following Cutaneous Injection in Human Atopic and Nonatopic Volunteers

    Andrew Menzies-Gow;Sun Ying;Ian Sabroe;Victoria L. Stubbs

  • Toll-Like Receptors in Health and Disease: Complex Questions Remain

    Ian Sabroe;Robert C. Read;Moira K. B. Whyte;David H. Dockrell

  • The role of interleukin-8 and its receptors in inflammatory lung disease: implications for therapy.

    James E. Pease;Ian Sabroe

  • The role of TLRs in neutrophil activation.

    Lynne R Prince;Moira K Whyte;Ian Sabroe;Lisa C Parker

  • Translational mini-review series on Toll-like receptors: networks regulated by Toll-like receptors mediate innate and adaptive immunity.

    L. C. Parker;L. R. Prince;I. Sabroe

  • The role of TLR activation in inflammation

    I Sabroe;L C Parker;S K Dower;M K B Whyte

  • Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease.

    Andrei E. Medvedev;Ian Sabroe;Jeffrey D. Hasday;Stefanie N. Vogel

  • A Small Molecule Antagonist of Chemokine Receptors CCR1 and CCR3 POTENT INHIBITION OF EOSINOPHIL FUNCTION AND CCR3-MEDIATED HIV-1 ENTRY

    I Sabroe;MJ Peck;BJ Van Keulen;A Jorritsma

  • The Role of Toll-Like Receptors in the Regulation of Neutrophil Migration, Activation, and Apoptosis

    Ian Sabroe;Steven K. Dower;Moira K. B. Whyte

  • Invited review: Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease

    Andrei E. Medvedev;Ian Sabroe;Jeffrey D. Hasday;Stefanie N. Vogel

  • The expression and roles of Toll-like receptors in the biology of the human neutrophil

    Lisa C. Parker;Moira K. B. Whyte;Steven K. Dower;Ian Sabroe

  • Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice

    Sarah R. Walmsley;Edwin R. Chilvers;Alfred A. Thompson;Kathryn Vaughan

  • Differential Regulation of Eosinophil Chemokine Signaling Via CCR3 and Non-CCR3 Pathways

    Ian Sabroe;Adele Hartnell;Louise A. Jopling;Sandra Bel

  • Eotaxin is specifically cleaved by hookworm metalloproteases preventing its action in vitro and in vivo.

    Fiona J. Culley;Alan Brown;Dolores M. Conroy;Ian Sabroe

  • Toll-like receptor (TLR)2 and TLR4 agonists regulate CCR expression in human monocytic cells.

    Lisa C. Parker;Moira K. B. Whyte;Stefanie N. Vogel;Steven K. Dower

  • Agonists of toll-like receptor (TLR)2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factor.

    Jon R. Ward;Lynne Bingle;Heather M. Judge;Simon B. Brown

  • Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish.

    A. A. Roger Thompson;Philip M. Elks;Helen M. Marriott;Suttida Eamsamarng

  • TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation.

    Emmet E. McGrath;Helen M. Marriott;Allan Lawrie;Sheila E. Francis

Frequent Co-Authors

Moira K. B. Whyte
Moira K. B. Whyte University of Edinburgh
David H. Dockrell
David H. Dockrell University of Edinburgh
Steven K. Dower
Steven K. Dower CSL (Australia)
James E. Pease
James E. Pease Imperial College London
Stephen A. Renshaw
Stephen A. Renshaw University of Sheffield
Timothy J. Williams
Timothy J. Williams National Institutes of Health
Robert F. Storey
Robert F. Storey University of Sheffield
Clare M. Lloyd
Clare M. Lloyd Imperial College London
Stephen J. Till
Stephen J. Till King's College London
Edwin R. Chilvers
Edwin R. Chilvers Imperial College London

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