World's Best Scientists 2026 revealed!

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Immunology

D-Index
74
Citations
23357
World Ranking
2038
National Ranking
178

Research.com Recognitions

  • 2018 - Fellow of the Royal Society of Edinburgh
  • 2017 - Member of Academia Europaea

Overview

Moira K. B. Whyte is affiliated with the University of Sheffield in the United Kingdom and has a research focus primarily in the fields of medicine and immunology and microbiology. Their work includes significant contributions to pulmonary and respiratory medicine, immunology, epidemiology, cancer research, and general health professions.

The scientist's main topics of study center on respiratory health and immune mechanisms. These include:

  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Immune cells in cancer
  • Cancer, Hypoxia, and Metabolism
  • Neonatal Respiratory Health Research
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Pulmonary Hypertension Research and Treatments

Frequent co-authors associated with Moira K. B. Whyte's research include Sarah R. Walmsley, Pranvera Sadiku, Emily Watts, Tyler Morrison, and Patrícia Coelho.

Their recent papers highlight a focus on immune responses, lung injury, and health system workforce sustainability. Notable publications include:

  • "Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis," 2020, Cell Metabolism
  • "Securing a sustainable and fit-for-purpose UK health and care workforce," 2021, The Lancet
  • "Neutrophil HIF-1α stabilization is augmented by mitochondrial ROS produced via the glycerol 3-phosphate shuttle," 2021, Blood
  • "LSE-Lancet Commission on the future of the NHS: re-laying the foundations for an equitable and efficient health and care service after COVID-19," 2021, The Lancet
  • "Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation," 2022, Nature Immunology

Moira K. B. Whyte has published multiple times in key venues including bioRxiv (Cold Spring Harbor Laboratory), Wellcome Open Research, Nature Immunology, ERJ Open Research, and Cell Metabolism. Their contributions are distributed notably with seven publications in bioRxiv and multiple publications in Wellcome Open Research and Nature Immunology.

Their academic standing is recognized through several awards such as Fellowship of the Royal Society of Edinburgh awarded in 2018 and membership in Academia Europaea granted in 2017.

Best Publications

  • Succinate is an inflammatory signal that induces IL-1β through HIF-1α

    G. M. Tannahill;A. M. Curtis;J. Adamik;E. M. Palsson-McDermott

  • The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages

    Marc Daigneault;Julie A. Preston;Helen M. Marriott;Moira K. B. Whyte

  • A transgenic zebrafish model of neutrophilic inflammation.

    Stephen A. Renshaw;Catherine A. Loynes;Daniel M.I. Trushell;Stone Elworthy

  • Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators.

    Alison Lee;Moira K.B. Whyte;Christopher Haslett

  • Impairment of function in aging neutrophils is associated with apoptosis.

    M. K. B. Whyte;L. C. Meagher;J. Macdermot;C. Haslett

  • Toll-Like Receptor (TLR)2 and TLR4 in Human Peripheral Blood Granulocytes: A Critical Role for Monocytes in Leukocyte Lipopolysaccharide Responses

    Ian Sabroe;Elizabeth C. Jones;Lynne R. Usher;Moira K. B. Whyte

  • APOPTOSIS AND THE CELL CYCLE

    Gerard I Evan;Lamorna Brown;Moira Whyte;Elizabeth Harrington

  • Selective Roles for Toll-Like Receptor (TLR)2 and TLR4 in the Regulation of Neutrophil Activation and Life Span

    Ian Sabroe;Lynne R. Prince;Elizabeth C. Jones;Malcolm J. Horsburgh

  • Pyocyanin Production by Pseudomonas aeruginosa Induces Neutrophil Apoptosis and Impairs Neutrophil-Mediated Host Defenses In Vivo

    Lucy Allen;David H. Dockrell;Theresa Pattery;Daniel G. Lee

  • Toll-Like Receptors in Health and Disease: Complex Questions Remain

    Ian Sabroe;Robert C. Read;Moira K. B. Whyte;David H. Dockrell

  • Induction of neutrophil apoptosis by the Pseudomonas aeruginosa exotoxin pyocyanin: a potential mechanism of persistent infection.

    Lynne R. Usher;Roderick A. Lawson;Ian Geary;Christopher J. Taylor

  • Alveolar Macrophage Apoptosis Contributes to Pneumococcal Clearance in a Resolving Model of Pulmonary Infection

    David H. Dockrell;Helen M. Marriott;Lynne R. Prince;Victoria C. Ridger

  • The role of TLRs in neutrophil activation.

    Lynne R Prince;Moira K Whyte;Ian Sabroe;Lisa C Parker

  • Granulocyte Apoptosis and the Control of Inflammation

    C. Haslett;J. S. Savill;M. K. B. Whyte;M. Stern

  • The role of TLR activation in inflammation

    I Sabroe;L C Parker;S K Dower;M K B Whyte

  • Increased Risk of Fibrosing Alveolitis Associated with Interleukin-1 Receptor Antagonist and Tumor Necrosis Factor- α Gene Polymorphisms

    M. Whyte;R. Hubbard;R. Meliconi;M. Whidborne

  • The Role of Toll-Like Receptors in the Regulation of Neutrophil Migration, Activation, and Apoptosis

    Ian Sabroe;Steven K. Dower;Moira K. B. Whyte

  • Exon skipping in Mcl-1 results in a bcl-2 homology domain 3 only gene product that promotes cell death.

    Colin D. Bingle;Ruth W. Craig;Brenka M. Swales;Vanessa Singleton

  • The expression and roles of Toll-like receptors in the biology of the human neutrophil

    Lisa C. Parker;Moira K. B. Whyte;Steven K. Dower;Ian Sabroe

  • A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism

    Anne L. Robertson;Geoffrey R. Holmes;Aleksandra N. Bojarczuk;Joseph Burgon

  • Acceleration of human neutrophil apoptosis by TRAIL.

    Stephen A. Renshaw;Jasvir S. Parmar;Vanessa Singleton;Sarah J. Rowe

Frequent Co-Authors

Ian Sabroe
Ian Sabroe University of Sheffield
David H. Dockrell
David H. Dockrell University of Edinburgh
Stephen A. Renshaw
Stephen A. Renshaw University of Sheffield
Steven K. Dower
Steven K. Dower CSL (Australia)
Edwin R. Chilvers
Edwin R. Chilvers Imperial College London
Philip W. Ingham
Philip W. Ingham University of Bath
Paul G. Hellewell
Paul G. Hellewell Brunel University London
Robert C. Read
Robert C. Read University of Southampton
Timothy J. Mitchell
Timothy J. Mitchell University of Birmingham
Kai-Håkon Carlsen
Kai-Håkon Carlsen University of Oslo

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