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Cecilia M. Canessa

Cecilia M. Canessa

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
15828
World Ranking
17429
National Ranking
478

Overview

Cecilia M. Canessa is affiliated with Tsinghua University in China. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with a notable emphasis on Molecular Biology. Additional areas of study include Immunology, Genetics, Cellular and Molecular Neuroscience, and Cell Biology.

The scientist's main research topics involve:

  • Ion channel regulation and function
  • Ion Transport and Channel Regulation
  • Toxin Mechanisms and Immunotoxins
  • Venomous Animal Envenomation and Studies
  • Sphingolipid Metabolism and Signaling
  • Neuroscience and Neuropharmacology Research
  • Endoplasmic Reticulum Stress and Disease

Recent publications by Cecilia M. Canessa include:

  • Structure and analysis of nanobody binding to the human ASIC1a ion channel, 2021, published in eLife
  • An arginine residue in the outer segment of hASIC1a TM1 affects both proton affinity and channel desensitization, 2021, published in The Journal of General Physiology
  • A flexible GAS belt responds to pore mutations changing the ion selectivity of proton-gated channels, 2021, published in The Journal of General Physiology
  • Lipid droplets and autophagosomes together with chaperones fine-tune expression of SGK1, 2022, published in Journal of Cellular and Molecular Medicine
  • Phosphatases maintain low catalytic activity of SGK1: DNA damage resets the balance in favor of phosphorylation, 2023, published in Journal of Biological Chemistry

Frequent publication venues include:

  • The Journal of General Physiology
  • eLife
  • Journal of Cellular and Molecular Medicine
  • Journal of Biological Chemistry

Among frequent co-authors collaborating with Cecilia M. Canessa are:

  • Zhuyuan Chen
  • Wenxue Gu
  • Yangyu Wu
  • Fred J. Sigworth
  • Georg Kuenze

Best Publications

  • Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits.

    Cecilia M. Canessa;Laurent Schild;Gary Buell;Bernard Thorens

  • Liddle's syndrome: heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel

    Richard A. Shimkets;David G. Warnock;Christopher M. Bositis;Carol Nelson-Williams

  • CFTR as a cAMP-dependent regulator of sodium channels.

    MJ Stutts;CM Canessa;JC Olsen;M Hamrick

  • Epithelial sodium channel related to proteins involved in neurodegeneration

    Cecilia M. Canessa;Jean-Daniel Horisberger;Bernard C. Rossier

  • Hypertension caused by a truncated epithelial sodium channel γ subunit: genetic heterogeneity of Liddle syndrome

    Joni H. Hansson;Carol Nelson-Williams;Hiroshi Suzuki;Laurent Schild

  • sgk Is an Aldosterone-induced Kinase in the Renal Collecting Duct EFFECTS ON EPITHELIAL Na+ CHANNELS

    Anikó Náray-Fejes-Tóth;Cecilia Canessa;Emily S. Cleaveland;George Aldrich

  • Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry.

    C Duc;N Farman;C M Canessa;J P Bonvalet

  • The Activity of the Epithelial Sodium Channel Is Regulated by Clathrin-mediated Endocytosis

    Richard A. Shimkets;Richard P. Lifton;Cecilia M. Canessa

  • Membrane topology of the epithelial sodium channel in intact cells.

    C. M. Canessa;A. M. Merillat;B. C. Rossier

  • A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system

    Laurent Schild;Cecilia M. Canessa;Richard A. Shimkets;Ivan Gautschi

  • Structure and Regulation of Amiloride-Sensitive Sodium Channels

    Diego Alvarez de la Rosa;Cecilia M. Canessa;Gregor K. Fyfe;Ping Zhang

  • The Serum and Glucocorticoid Kinase sgk Increases the Abundance of Epithelial Sodium Channels in the Plasma Membrane of Xenopus Oocytes

    Diego Alvarez de la Rosa;Ping Zhang;Anikó Náray-Fejes-Tóth;Géza Fejes-Tóth

  • Diversity of channels generated by different combinations of epithelial sodium channel subunits.

    Carmel M. McNicholas;Cecilia M. Canessa

  • Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous system

    Diego Alvarez de la Rosa;Ping Zhang;Deren Shao;Fletcher White

  • In vivo phosphorylation of the epithelial sodium channel.

    Richard A. Shimkets;Richard Lifton;Cecilia M. Canessa

  • Epithelial sodium channels.

    Bernard C. Rossier;Cecilia M. Canessa;Laurent Schild;Jean-Daniel Horisberger

  • Primary sequence and functional expression of a novel ouabain-resistant Na,K-ATPase. The beta subunit modulates potassium activation of the Na,K-pump.

    F Jaisser;C M Canessa;J D Horisberger;B C Rossier

  • Distribution, subcellular localization and ontogeny of ASIC1 in the mammalian central nervous system.

    Diego Alvarez de la Rosa;Stefan R. Krueger;Annette Kolar;Deren Shao

  • Transforming Growth Factor-β1 Decreases Expression of the Epithelial Sodium Channel αENaC and Alveolar Epithelial Vectorial Sodium and Fluid Transport via an ERK1/2-dependent Mechanism

    James Frank;Jérémie Roux;Hisaaki Kawakatsu;George Su

  • Interleukin-1β Decreases Expression of the Epithelial Sodium Channel α-Subunit in Alveolar Epithelial Cells via a p38 MAPK-dependent Signaling Pathway *

    Jérémie Roux;Hisaaki Kawakatsu;Brandi Gartland;Melissa Pespeni

Frequent Co-Authors

Bernard C. Rossier
Bernard C. Rossier University of Lausanne
Jean-Daniel Horisberger
Jean-Daniel Horisberger University of Lausanne
Richard P. Lifton
Richard P. Lifton Rockefeller University
Ali Mobasheri
Ali Mobasheri University of Oulu
Eduardo Salido
Eduardo Salido Hospital Universitario de Canarias
David G. Warnock
David G. Warnock University of Alabama at Birmingham
Morris Schambelan
Morris Schambelan University of California, San Francisco
Richard C. Boucher
Richard C. Boucher University of North Carolina at Chapel Hill
Peter Jonas
Peter Jonas Institute of Science and Technology Austria
Nail Burnashev
Nail Burnashev Aix-Marseille University

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