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Bernard C. Rossier

Bernard C. Rossier

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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
93
Citations
33667
World Ranking
2089
National Ranking
47

Medicine

D-Index
93
Citations
33890
World Ranking
10832
National Ranking
147

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award
  • 2002 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Physiology and Pharmacology/Toxicology
  • 1999 - Fellow of the American Academy of Arts and Sciences
  • 1992 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Bernard C. Rossier is affiliated with the University of Lausanne in Switzerland. Their research contributions span several domains within molecular biology and medicine, particularly focusing on ion transport and channel regulation.

The scientist has contributed papers mainly in settings addressing epithelial sodium channels and related physiological processes. Some recent papers include:

  • A Pathophysiological Model for COVID-19: Critical Importance of Transepithelial Sodium Transport upon Airway Infection, 2020, Function
  • Preferential Assembly of Epithelial Sodium Channel (ENaC) Subunits in Xenopus Oocytes: ROLE OF FURIN-MEDIATED ENDOGENOUS PROTEOLYSIS, 2020, UNC Libraries
  • SARS-CoV-2 et le transport de sodium: une stratégie diabolique, 2020, Revue Médicale Suisse
  • Arterielle Hypertonie: Verstehen, vorbeugen, behandeln, 2022, Swiss Medical Forum - Schweizerisches Medizin-Forum
  • Hypertension artérielle: comprendre, prévenir et traiter, 2022, Forum Médical Suisse - Swiss Medical Forum

Frequently collaborating with other researchers, notable co-authors include Martina Gentzsch, M. P. Harris, M. Jackson Stutts, Dmitri Firsov, and Agustín García-Caballero.

Bernard C. Rossier's work has been published predominantly in the following venues:

  • UNC Libraries
  • Function
  • Revue Médicale Suisse
  • Swiss Medical Forum - Schweizerisches Medizin-Forum
  • Forum Médical Suisse - Swiss Medical Forum

Their research fields cover molecular biology along with subfields such as sensory systems and pulmonary and respiratory medicine. The main research topics involve:

  • Ion Transport and Channel Regulation
  • Ion channel regulation and function
  • Ion Channels and Receptors
  • Electrolyte and hormonal disorders

Bernard C. Rossier has received several recognitions including membership and fellowships:

  • Member of Academia Europaea (1992)
  • Fellow of the American Academy of Arts and Sciences (1999)
  • German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina - Nationale Akademie der Wissenschaften (2002) in Physiology and Pharmacology/Toxicology
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits.

    Cecilia M. Canessa;Laurent Schild;Gary Buell;Bernard Thorens

  • Liddle's syndrome: heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel

    Richard A. Shimkets;David G. Warnock;Christopher M. Bositis;Carol Nelson-Williams

  • CFTR as a cAMP-dependent regulator of sodium channels.

    MJ Stutts;CM Canessa;JC Olsen;M Hamrick

  • Epithelial sodium channel related to proteins involved in neurodegeneration

    Cecilia M. Canessa;Jean-Daniel Horisberger;Bernard C. Rossier

  • Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice

    Edith Hummler;Pierre Barker;John Gatzy;Friedrich Beermann

  • Hypertension caused by a truncated epithelial sodium channel γ subunit: genetic heterogeneity of Liddle syndrome

    Joni H. Hansson;Carol Nelson-Williams;Hiroshi Suzuki;Laurent Schild

  • Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1

    Sue S. Chang;Stefan Grunder;Aaron Hanukoglu;Ariel Rösler

  • An epithelial serine protease activates the amiloride-sensitive sodium channel

    Vronique Vallet;Ahmed Chraibi;Hans-Peter Gaeggeler;Jean-Daniel Horisberger

  • Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry.

    C Duc;N Farman;C M Canessa;J P Bonvalet

  • A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity

    Joni H. Hansson;Laurent Schild;Yin Lu;Thomas A. Wilson

  • The heterotetrameric architecture of the epithelial sodium channel (ENaC)

    Dmitri Firsov;Ivan Gautschi;Anne‐Marie Merillat;Bernard C. Rossier

  • Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5.

    Joost G.J. Hoenderop;Johannes P.T.M. van Leeuwen;Bram C.J. van der Eerden;Ferry F.J. Kersten

  • Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome.

    L Schild;Y Lu;I Gautschi;E Schneeberger

  • Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: A quantitative approach

    Dmitri Firsov;Laurent Schild;Ivan Gautschi;Anne-Marie Mérillat

  • Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK.

    Johannes Loffing;Marija Zecevic;Eric Féraille;Brigitte Kaissling

  • Epithelial Sodium Channel and the Control of Sodium Balance: Interaction Between Genetic and Environmental Factors

    Bernard C. Rossier;Sylvain Pradervand;Laurent Schild;Edith Hummler

  • Membrane topology of the epithelial sodium channel in intact cells.

    C. M. Canessa;A. M. Merillat;B. C. Rossier

  • Lithium nephrotoxicity revisited

    Jean-Pierre Grünfeld;Bernard C. Rossier

  • Corticosteroid-Dependent Sodium Transport in a Novel Immortalized Mouse Collecting Duct Principal Cell Line

    Marcelle Bens;Véronique Vallet;Françoise Cluzeaud;Laurent Pascual-Letallec

  • A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system

    Laurent Schild;Cecilia M. Canessa;Richard A. Shimkets;Ivan Gautschi

Frequent Co-Authors

Käthi Geering
Käthi Geering University of Lausanne
Jean-Daniel Horisberger
Jean-Daniel Horisberger University of Lausanne
Cecilia M. Canessa
Cecilia M. Canessa Tsinghua University
Jean-Pierre Kraehenbuhl
Jean-Pierre Kraehenbuhl University of Lausanne
Richard P. Lifton
Richard P. Lifton Rockefeller University
Friedrich Beermann
Friedrich Beermann École Polytechnique Fédérale de Lausanne
Richard C. Boucher
Richard C. Boucher University of North Carolina at Chapel Hill
François Verrey
François Verrey University of Zurich
Michel Burnier
Michel Burnier University of Lausanne

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