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Joost G. J. Hoenderop

Joost G. J. Hoenderop

D-Index & Metrics

Biology and Biochemistry

D-Index
97
Citations
33767
World Ranking
1752
National Ranking
33

Medicine

D-Index
98
Citations
34119
World Ranking
8945
National Ranking
350

Research.com Recognitions

  • 2018 - Member of Academia Europaea

Overview

Joost G. J. Hoenderop is a researcher affiliated with Radboud University in the Netherlands. Their work spans multiple interconnected domains within biochemistry, genetics, molecular biology, and medicine, with a prominent focus on nephrology and related fields.

The scientist has a substantial publication record, prominently contributing to the understanding of magnesium in health and disease, renal and related cancers, parathyroid disorders and treatments, ion transport and channel regulation, genetic and kidney cyst diseases, plant micronutrient interactions and effects, and extracellular vesicles in disease.

Hoenderop's recent scholarly articles include several that address key physiological and pathological mechanisms:

  • Mechanisms of proton pump inhibitor-induced hypomagnesemia (2022), published in Acta Physiologica
  • Comparing Approaches to Normalize, Quantify, and Characterize Urinary Extracellular Vesicles (2021), published in Journal of the American Society of Nephrology
  • Nephron mass determines the excretion rate of urinary extracellular vesicles (2022), published in Journal of Extracellular Vesicles
  • Sensing of tubular flow and renal electrolyte transport (2020), published in Nature Reviews Nephrology
  • Magnesium Disorders (2024), published in New England Journal of Medicine

Frequent collaborators in their research include:

  • Jeroen H. F. de Baaij (57 joint publications)
  • Caro Bos (21 joint publications)
  • Jenny van der Wijst (13 joint publications)
  • René J.M. Bindels (12 joint publications)
  • Femke Latta (12 joint publications)

The venues where Hoenderop has published most extensively include:

  • Journal of the American Society of Nephrology (11 publications)
  • The FASEB Journal (10 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (6 publications)
  • Scientific Reports (5 publications)
  • American Journal of Physiology-Renal Physiology (4 publications)

Their scientific output is concentrated largely within the fields of Biochemistry, Genetics and Molecular Biology with 97 publications, and Medicine with 76 publications. More specialized subfields include Molecular Biology, Nutrition and Dietetics, Nephrology, Genetics, and Plant Science.

Joost G. J. Hoenderop's research topics are geared toward physiological and pathological mechanisms relating to magnesium metabolism, kidney function, and cellular vesicle biology. Their work integrates molecular techniques and clinical insights to further clarify conditions such as hypomagnesemia and electrolyte transport disorders.

Hoenderop has been recognized as a Member of Academia Europaea since 2018, reflecting their engagement in the broader European scientific community.

Best Publications

  • Magnesium in Man: Implications for Health and Disease

    Jeroen H. F. de Baaij;Joost G. J. Hoenderop;René J. M. Bindels

  • Calcium Absorption Across Epithelia

    Joost G. J. Hoenderop;Bernd Nilius;René J. M. Bindels

  • Molecular Identification of the Apical Ca2+Channel in 1,25-Dihydroxyvitamin D3-responsive Epithelia *

    J.G.J. Hoenderop;J.W.C.M. van der Kemp;A. Hartog;K.F.J. van de Graaf

  • The ß-Glucuronidase Klotho Hydrolyzes and Activates the TRPV5 Channel

    Q. Chang;S.J.G. Hoefs;J.W.C.M. van der Kemp;C.N. Topala

  • Duodenal calcium absorption in vitamin D receptor-knockout mice: functional and molecular aspects.

    Sophie J. Van Cromphaut;Mieke Dewerchin;Joost G. J. Hoenderop;Ingrid Stockmans

  • Mutations in CYP24A1 and Idiopathic Infantile Hypercalcemia

    Karl P. Schlingmann;Martin Kaufmann;Stefanie Weber;Andrew Irwin

  • TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption.

    Thomas Voets;Bernd Nilius;Susan Hoefs;Annemiete W.C.M. van der Kemp

  • Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia

    Tom Nijenhuis;Volker Vallon;Annemiete W.C.M. van der Kemp;Johannes Loffing

  • Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5.

    Joost G.J. Hoenderop;Johannes P.T.M. van Leeuwen;Bram C.J. van der Eerden;Ferry F.J. Kersten

  • Homo‐ and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6

    J G J Hoenderop;Thomas Voets;S Hoefs;F Weidema

  • Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia

    Wouter M. Tiel Groenestege;Stéphanie Thébault;Jenny van der Wijst;Dennis van den Berg

  • Permeation and gating properties of the novel epithelial Ca(2+) channel.

    Rudi Vennekens;Joost G.J. Hoenderop;Jean Prenen;Marchel Stuiver

  • Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release

    F.J.M. van Kuppeveld;J.G.J. Hoenderop;R.L.L. Smeets;P.H.G.M. Willems

  • Function and expression of the epithelial Ca2+ channel family: comparison of mammalian ECaC1 and 2

    Joost G. J. Hoenderop;Rudi Vennekens;Dominik Müller;Jean Prenen

  • Calcitriol Controls the Epithelial Calcium Channel in Kidney

    Joost G. J. Hoenderop;Dominik Müller;Annemiete W. C. M. Van Der Kemp;Anita Hartog

  • Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex.

    Stan F.J. van de Graaf;Joost G.J. Hoenderop;Dimitra Gkika;Dennis Lamers

  • Modulation of renal Ca2+ transport protein genes by dietary Ca2+ and 1,25-dihydroxyvitamin D3 in 25-hydroxyvitamin D3-1alpha-hydroxylase knockout mice.

    Joost G J Hoenderop;Olivier Dardenne;Monique Van Abel;Annemiete W C M Van Der Kemp

  • Distribution of transcellular calcium and sodium transport pathways along mouse distal nephron.

    Johannes Loffing;Dominique Loffing-Cueni;Victor Valderrabano;L. E. A. Kläusli

  • Hypomagnesemia in Type 2 Diabetes: A Vicious Circle?

    Lisanne M.M. Gommers;Joost G.J. Hoenderop;René J.M. Bindels;Jeroen H.F. de Baaij;Jeroen H.F. de Baaij

  • Molecular Mechanism of Active Ca2+ Reabsorption in the Distal Nephron

    Joost G J Hoenderop;Bernd Nilius;Rene J M Bindels

Frequent Co-Authors

René J. M. Bindels
René J. M. Bindels Radboud University
Bernd Nilius
Bernd Nilius KU Leuven
Peter H. G. M. Willems
Peter H. G. M. Willems Radboud University
Nine V.A.M. Knoers
Nine V.A.M. Knoers University Medical Center Groningen
Jean Prenen
Jean Prenen KU Leuven
Jack F.M. Wetzels
Jack F.M. Wetzels Radboud University
Guy Droogmans
Guy Droogmans KU Leuven
Johan van der Vlag
Johan van der Vlag Radboud University
Olivier Devuyst
Olivier Devuyst University of Zurich
Hanka Venselaar
Hanka Venselaar Radboud University

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