D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 80 Citations 16,372 247 World Ranking 325 National Ranking 36

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Bacteria

Timothy J. Mitchell mostly deals with Microbiology, Streptococcus pneumoniae, Pneumolysin, Virulence and Immunology. The concepts of his Microbiology study are interwoven with issues in Meningitis, Cellular infiltration, Mutant and In vivo. Timothy J. Mitchell works in the field of Streptococcus pneumoniae, focusing on Pneumococcal infections in particular.

The study incorporates disciplines such as Virulence factor, Toxin, Complement system and Lung injury, Lung in addition to Pneumolysin. His Virulence research is multidisciplinary, incorporating perspectives in Autolysin, Disease and Bacteria. His Immunology study incorporates themes from Peripheral blood mononuclear cell, Pneumococcal pneumonia and Pneumonia.

His most cited work include:

  • Rapid Pneumococcal Evolution in Response to Clinical Interventions (730 citations)
  • A highly conserved repeated DNA element located in the chromosome of Streptococcus pneumoniae. (346 citations)
  • Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species (283 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Microbiology, Streptococcus pneumoniae, Pneumolysin, Immunology and Virulence. His biological study spans a wide range of topics, including Virulence factor, Antibody, Gene and Bacteria. His biological study focuses on Pneumococcal infections.

Timothy J. Mitchell works mostly in the field of Pneumolysin, limiting it down to concerns involving Cell biology and, occasionally, Programmed cell death. His Immunology research incorporates themes from Lung injury, Lung, Pneumococcal pneumonia and Pneumonia. His Virulence research is classified as research in Genetics.

He most often published in these fields:

  • Microbiology (53.85%)
  • Streptococcus pneumoniae (52.66%)
  • Pneumolysin (50.30%)

What were the highlights of his more recent work (between 2014-2021)?

  • Pneumolysin (50.30%)
  • Immunology (30.47%)
  • Streptococcus pneumoniae (52.66%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Pneumolysin, Immunology, Streptococcus pneumoniae, Microbiology and Pneumonia. The Pneumolysin study combines topics in areas such as Pathogenesis, Extracellular, Cell biology, Lung and Innate immune system. His Immunology research integrates issues from Lung injury and Pneumococcal pneumonia.

His research in Streptococcus pneumoniae intersects with topics in Human pathogen, Genome, Genomics and Genetic variation. His work deals with themes such as Immune system, Intracellular and Virulence, which intersect with Microbiology. Timothy J. Mitchell has included themes like Molecular epidemiology, Angiopoietin receptor and Virology in his Pneumonia study.

Between 2014 and 2021, his most popular works were:

  • Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets (94 citations)
  • Active release of pneumolysin prepores and pores by mammalian cells undergoing a Streptococcus pneumoniae attack (40 citations)
  • Pneumolysin induced mitochondrial dysfunction leads to release of mitochondrial DNA. (27 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Bacteria

Timothy J. Mitchell focuses on Pneumolysin, Immunology, Streptococcus pneumoniae, Pneumonia and Microbiology. His Pneumolysin study deals with Cell biology intersecting with Liberation, Intrinsic apoptosis, Mitochondrial membrane transport protein and Mitochondrial permeability transition pore. In his research on the topic of Streptococcus pneumoniae, Immune system, Antigen, Antibody, Lymphatic system and Stimulation is strongly related with Cytokine.

His Pneumonia research is multidisciplinary, relying on both Inflammasome, Sepsis, Virology, Lung and Pneumococcal pneumonia. His studies deal with areas such as ESCRT and Plasma membrane repair as well as Microbiology. His Serotype research includes elements of Virulence factor and Innate immune system.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Rapid Pneumococcal Evolution in Response to Clinical Interventions

Nicholas J. Croucher;Simon R. Harris;Christophe Fraser;Michael A. Quail.
Science (2011)

846 Citations

A highly conserved repeated DNA element located in the chromosome of Streptococcus pneumoniae.

Bernard Martin;Odile Humbert;Miguel Camara;Eric Guenzi.
Nucleic Acids Research (1992)

500 Citations

Pneumococcal pneumolysin and H2O2 mediate brain cell apoptosis during meningitis

Johann S. Braun;Jack E. Sublett;Dorette Freyer;Tim J. Mitchell.
Journal of Clinical Investigation (2002)

363 Citations

The pathogenesis of streptococcal infections: from Tooth decay to meningitis

Timothy J. Mitchell.
Nature Reviews Microbiology (2003)

361 Citations

Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species

Claudio Donati;N. Luisa Hiller;Hervé Tettelin;Alessandro Muzzi.
Genome Biology (2010)

356 Citations

Molecular Analysis of The Pathogenicity of Streptococcus Pneumoniae: The Role of Pneumococcal Proteins

Jc Paton;Pw Andrew;Gj Boulnois;Tj Mitchell.
Annual Review of Microbiology (1993)

350 Citations

Competence-programmed predation of noncompetent cells in the human pathogen Streptococcus pneumoniae: Genetic requirements

Sébastien Guiral;Tim J. Mitchell;Bernard Martin;Jean-Pierre Claverys.
Proceedings of the National Academy of Sciences of the United States of America (2005)

341 Citations

Streptococcus pneumoniae: virulence factors and variation

A.M. Mitchell;T.J. Mitchell.
Clinical Microbiology and Infection (2010)

311 Citations

Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcus pneumoniae.

J. E. Alexander;R. A. Lock;C. C. A. M. Peeters;J. T. Poolman.
Infection and Immunity (1994)

270 Citations

Microarray-based identification of a novel Streptococcus pneumoniae regulon controlled by an autoinduced peptide

Antoine de Saizieu;Christophe Gardès;Nicholas Flint;Christian Wagner.
Journal of Bacteriology (2000)

268 Citations

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