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Microbiology

D-Index
44
Citations
8123
World Ranking
5125
National Ranking
434

Overview

Stuart C. Clarke is affiliated with the University of Southampton in the United Kingdom. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with a focus on epidemiology, molecular medicine, endocrinology, microbiology, and molecular biology as key subfields.

The scientist's work covers various topics related to infectious diseases and microbiology. These include:

  • Pneumonia and Respiratory Infections
  • Antibiotic Resistance in Bacteria
  • Respiratory Viral Infections Research
  • Bacterial Infections and Vaccines
  • Vibrio Bacteria Research Studies
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Gut Microbiota and Health

Stuart C. Clarke has contributed to a series of recent publications demonstrating a strong focus on bacterial epidemiology and antimicrobial resistance, particularly involving pneumococci and other pathogens. Notable papers include:

  • "Changes in serotype prevalence of Streptococcus pneumoniae in Southampton, UK between 2006 and 2018" (2022) published in Scientific Reports
  • "The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci" (2021) in eLife
  • "The upper respiratory tract microbiome of indigenous Orang Asli in north-eastern Peninsular Malaysia" (2021) in npj Biofilms and Microbiomes
  • "Complete Genome Sequencing of Acinetobacter baumannii AC1633 and Acinetobacter nosocomialis AC1530 Unveils a Large Multidrug-Resistant Plasmid Encoding the NDM-1 and OXA-58 Carbapenemases" (2021) in mSphere
  • "International links between Streptococcus pneumoniae vaccine serotype 4 sequence type (ST) 801 in Northern European shipyard outbreaks of invasive pneumococcal disease" (2022) in Vaccine

The scientist frequently publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Pneumonia
  • Microbial Genomics
  • International Journal of Infectious Diseases
  • ERJ Open Research

Collaboration is evident through repeated coauthorship with several researchers, including:

  • David Cleary
  • Chew Chieng Yeo
  • Nor Iza A. Rahman
  • Salwani Ismail
  • Ahmed Ghazi Alattraqchi

Overall, Stuart C. Clarke's research contributions focus on understanding the epidemiology, genetic evolution, and resistance mechanisms of bacterial pathogens, particularly those affecting respiratory health. Their work integrates molecular approaches with clinical and population data to inform infectious disease dynamics.

Best Publications

  • Secondary Bacterial Infections Associated with Influenza Pandemics.

    Denise E. Morris;David W. Cleary;Stuart C. Clarke

  • Impact of meningococcal serogroup C conjugate vaccines on carriage and herd immunity

    Martin C. J. Maiden;Ana Belén Ibarz-Pavón;Rachel Urwin;Stephen J. Gray

  • Virulence of Enteropathogenic Escherichia coli, a Global Pathogen

    S. C. Clarke;R. D. Haigh;P. P. E. Freestone;P. H. Williams

  • Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study.

    Stephanie W Lo;Rebecca A Gladstone;Andries J van Tonder;John A Lees

  • Longitudinal profiling of the lung microbiome in the AERIS study demonstrates repeatability of bacterial and eosinophilic COPD exacerbations

    David Mayhew;Nathalie Devos;Christophe Lambert;James R Brown

  • Diarrhoeagenic Escherichia coli—an emerging problem?

    Stuart C. Clarke

  • A prospective, observational cohort study of the seasonal dynamics of airway pathogens in the aetiology of exacerbations in COPD

    Tom M A Wilkinson;Emmanuel Aris;Simon Bourne;Simon Bourne;Stuart C Clarke

  • Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis.

    Robert P Howlin;Katrina Cathie;Katrina Cathie;Luanne Hall-Stoodley;Luanne Hall-Stoodley;Victoria Cornelius

  • Pseudomonas aeruginosa outbreaks in the neonatal intensive care unit--a systematic review of risk factors and environmental sources.

    J. M. C. Jefferies;J. M. C. Jefferies;T. Cooper;T. Yam;S. C. Clarke

  • Five winters of pneumococcal serotype replacement in UK carriage following PCV introduction.

    Rebecca A. Gladstone;Johanna M. Jefferies;Anna S. Tocheva;Kate R. Beard

  • Comparison of Commercial DNA Extraction Kits for Extraction of Bacterial Genomic DNA from Whole-Blood Samples

    K. Smith;M. A. Diggle;S. C. Clarke;S. C. Clarke

  • Interlaboratory Comparison of PCR-Based Identification and Genogrouping of Neisseria meningitidis

    Muhamed Kheir Taha;Jean Michel Alonso;Mary Cafferkey;Dominique A. Caugant;Dominique A. Caugant

  • Multilocus sequence typing: Data analysis in clinical microbiology and public health.

    Christopher B. Sullivan;Matthew A. Diggle;Stuart C. Clarke

  • Presence of Nonhemolytic Pneumolysin in Serotypes of Streptococcus pneumoniae Associated with Disease Outbreaks

    Johanna M C Jefferies;Calum H G Johnston;Lea-Ann S Kirkham;Graeme J M Cowan

  • Identification of Invasive Serotype 1 Pneumococcal Isolates That Express Nonhemolytic Pneumolysin

    Lea-Ann S. Kirkham;Johanna M. C. Jefferies;Alison R. Kerr;Yu Jing

  • Prevalence of Streptococcus pneumoniae serotypes causing invasive and non-invasive disease in South East Asia: a review

    E. Jauneikaite;J.M. Jefferies;J.M. Jefferies;M.L. Hibberd;S.C. Clarke;S.C. Clarke

  • Global emergence and population dynamics of divergent serotype 3 CC180 pneumococci

    Taj Azarian;Patrick K. Mitchell;Maria Georgieva;Claudette M. Thompson

  • Genetic Analysis of Diverse Disease-Causing Pneumococci Indicates High Levels of Diversity within Serotypes and Capsule Switching

    Johanna M. C. Jefferies;Andrew Smith;Stuart C. Clarke;Stuart C. Clarke;Chris Dowson

  • Invasive Pneumococcal Disease in Scotland, 1999–2001: Use of Record Linkage to Explore Associations between Patients and Disease in Relation to Future Vaccination Policy

    Moe H. Kyaw;Peter Christie;Stuart C. Clarke;John D. Mooney

  • Current methods for capsular typing of Streptococcus pneumoniae

    Elita Jauneikaite;Anna S. Tocheva;Johanna M.C. Jefferies;Rebecca A. Gladstone

  • Impact of Meningococcal Serogroup C Conjugate Vaccines on Carriage and Herd Immunity. Commentary

    David S. Stephens;Martin C. J. Maiden;Ana Belén Ibarz-Pavon;Rachel Urwin

Frequent Co-Authors

Saul N. Faust
Saul N. Faust University Hospital Southampton NHS Foundation Trust
Timothy J. Mitchell
Timothy J. Mitchell University of Birmingham
Jeremy S. Webb
Jeremy S. Webb University of Southampton
Stephen D. Bentley
Stephen D. Bentley Wellcome Sanger Institute
Luanne Hall-Stoodley
Luanne Hall-Stoodley The Ohio State University
Paul Stoodley
Paul Stoodley The Ohio State University
Paul Roderick
Paul Roderick University of Southampton
Martin Antonio
Martin Antonio London School of Hygiene & Tropical Medicine
Chris Robertson
Chris Robertson University of Strathclyde
Martin L. Hibberd
Martin L. Hibberd London School of Hygiene & Tropical Medicine

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