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D-Index & Metrics

Microbiology

D-Index
51
Citations
10810
World Ranking
4301
National Ranking
384

Overview

Aras Kadioglu is an active researcher affiliated with the University of Liverpool in the United Kingdom, specializing in the field of Medicine with a focus on infectious diseases and respiratory conditions.

Their primary fields of study include epidemiology, public health, environmental and occupational health, molecular biology, microbiology, and infectious diseases. This multidisciplinary expertise reflects in their research topics, which cover pneumonia and respiratory infections, respiratory viral infections research, bacterial infections and vaccines, bacterial biofilms and quorum sensing, Pneumocystis jirovecii pneumonia detection and treatment, streptococcal infections and treatments, and neonatal and maternal infections.

Kadioglu has published extensively in various scientific venues, frequently contributing to bioRxiv (Cold Spring Harbor Laboratory), Scientific Reports, SSRN Electronic Journal, Placenta, and Nature Communications.

Their recent publications demonstrate ongoing investigation into respiratory pathogens and air pollution interactions, including:

  • "Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin", 2020, Nature Communications
  • "Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease", 2020, Journal of Allergy and Clinical Immunology
  • "Exploiting lung adaptation and phage steering to clear pan-resistant Pseudomonas aeruginosa infections in vivo", 2024, Nature Communications
  • "Mechanistic Insights into the Impact of Air Pollution on Pneumococcal Pathogenesis and Transmission", 2022, American Journal of Respiratory and Critical Care Medicine
  • "Structure-Based Discovery of Lipoteichoic Acid Synthase Inhibitors", 2022, Journal of Chemical Information and Modeling

Kadioglu collaborates regularly with several coauthors, including Marie Yang, Murielle Baltazar, Neil French, Daniel R. Neill, and Shadia Khandaker, with whom they have multiple joint publications.

Their research broadly addresses critical questions in bacterial pathogenesis and respiratory infection mechanisms while also exploring environmental influences such as air pollution on disease progression and transmission.

Best Publications

  • The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease.

    Aras Kadioglu;Jeffrey N. Weiser;James C. Paton;Peter W. Andrew

  • Alternatives to antibiotics—a pipeline portfolio review

    Lloyd Czaplewski;Richard Bax;Martha Clokie;Mike Dawson

  • Pneumolysin Activates the NLRP3 Inflammasome and Promotes Proinflammatory Cytokines Independently of TLR4

    Edel A. McNeela;Áine Burke;Daniel R. Neill;Cathy Baxter

  • Switch from planktonic to sessile life: a major event in pneumococcal pathogenesis.

    Marco R. Oggioni;Claudia Trappetti;Aras Kadioglu;Marco Cassone

  • The role of pneumolysin in pneumococcal pneumonia and meningitis

    R. A. Hirst;A. Kadioglu;C. O'callaghan;P. W. Andrew

  • Host cellular immune response to pneumococcal lung infection in mice.

    Aras Kadioglu;Neill A. Gingles;Kate Grattan;Alison Kerr

  • Pneumococcal Neuraminidases A and B Both Have Essential Roles during Infection of the Respiratory Tract and Sepsis

    Sonia Manco;Fidelma Hernon;Hasan Yesilkaya;James C. Paton

  • Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+ Efflux

    Mausita Karmakar;Michael Katsnelson;Hesham A. Malak;Neil G. Greene

  • Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice

    Brian D Henry;Daniel R Neill;Katrin Anne Becker;Suzanna Gore

  • Phage therapy is highly effective against chronic lung infections with Pseudomonas aeruginosa

    Elaine M Waters;Daniel R Neill;Basak Kaman;Jaspreet S Sahota

  • Role of manganese-containing superoxide dismutase in oxidative stress and virulence of Streptococcus pneumoniae.

    Hasan Yesilkaya;Aras Kadioglu;Neill Gingles;Janet E. Alexander

  • The innate immune response to pneumococcal lung infection: the untold story

    Aras Kadioglu;Peter W. Andrew

  • The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection

    Youssif M. Ali;Nicholas J. Lynch;Kashif S. Haleem;Teizo Fujita

  • Controlled Human Infection and Rechallenge with Streptococcus pneumoniae Reveals the Protective Efficacy of Carriage in Healthy Adults

    Daniela M. Ferreira;Daniel R. Neill;Mathieu Bangert;Jenna F. Gritzfeld

  • Sialic Acid: A Preventable Signal for Pneumococcal Biofilm Formation, Colonization, and Invasion of the Host

    Claudia Trappetti;Aras Kadioglu;Melissa Carter;Jasvinder Hayre

  • CD4-T-lymphocyte interactions with pneumolysin and pneumococci suggest a crucial protective role in the host response to pneumococcal infection.

    Aras Kadioglu;William Coward;M. Joseph Colston;Colin R. A. Hewitt

  • Upper and lower respiratory tract infection by Streptococcus pneumoniae is affected by pneumolysin deficiency and differences in capsule type.

    Aras Kadioglu;Sally Taylor;Francesco Iannelli;Gianni Pozzi

  • Protein Serine/Threonine Kinase StkP Positively Controls Virulence and Competence in Streptococcus pneumoniae

    Jose Echenique;Aras Kadioglu;Susana Romao;Peter W. Andrew

  • Role of genetic resistance in invasive pneumococcal infection: Identification and study of susceptibility and resistance in inbred mouse strains

    Neill A. Gingles;Janet E. Alexander;Aras Kadioglu;Peter W. Andrew

  • Capsule type of Streptococcus pneumoniae determines growth phenotype.

    Lucy J. Hathaway;Silvio D. Brugger;Brigitte Morand;Mathieu Bangert;Mathieu Bangert

  • Role of inflammatory mediators in resistance and susceptibility to pneumococcal infection

    Alison R. Kerr;June J. Irvine;Jennifer J. Search;Neill A. Gingles

Frequent Co-Authors

Peter W. Andrew
Peter W. Andrew University of Leicester
Dean Everett
Dean Everett Khalifa University
Neil French
Neil French University of Liverpool
Stephen B. Gordon
Stephen B. Gordon Liverpool School of Tropical Medicine
Craig Winstanley
Craig Winstanley University of Liverpool
Timothy J. Mitchell
Timothy J. Mitchell University of Birmingham
Robert S. Heyderman
Robert S. Heyderman University College London
Daniela M. Ferreira
Daniela M. Ferreira Liverpool School of Tropical Medicine
Stephen D. Bentley
Stephen D. Bentley Wellcome Sanger Institute
Martin Antonio
Martin Antonio London School of Hygiene & Tropical Medicine

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