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D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
8515
World Ranking
18376
National Ranking
7504

Overview

Pankaj K. Singh is affiliated with the University of Florida in the United States. Their research encompasses multiple fields including Biochemistry, Genetics and Molecular Biology, and Medicine. The primary focus areas within these fields include Molecular Biology, Cancer Research, Oncology, Cell Biology, and Surgery.

The scientist has contributed extensively to topics such as Cancer, Hypoxia, and Metabolism; Pancreatic and Hepatic Oncology Research; Epigenetics and DNA Methylation; Biochemical and Molecular Research; Cancer Research and Treatments; RNA modifications and cancer; and Autophagy in Disease and Therapy.

Notable recent papers include:

  • "Nucleotide metabolism: a pan-cancer metabolic dependency" (2023), published in Nature reviews. Cancer
  • "The cholesterol pathway: impact on immunity and cancer" (2021), published in Trends in Immunology
  • "Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression" (2021), published in Gastroenterology
  • "Monocyte metabolic reprogramming promotes pro-inflammatory activity and Staphylococcus aureus biofilm clearance" (2020), published in PLoS Pathogens
  • "Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer" (2022), published in Cancer Research

Frequent coauthors collaborating with Pankaj K. Singh include:

  • Surendra K. Shukla
  • Dezhen Wang
  • Kuldeep S. Attri
  • Nina V. Chaika
  • Divya Murthy

The scientist has published regularly in venues such as Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Cancer Letters, Nature reviews. Cancer, and Gastroenterology.

This researcher's work includes more than 150 publications in Biochemistry, Genetics and Molecular Biology and around 96 in Medicine, signifying a broad interdisciplinary engagement with cancer biology and related biochemical processes.

Best Publications

  • Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

    Kirsten L. Bryant;Clint A. Stalnecker;Daniel Zeitouni;Jennifer E. Klomp

  • Sonic hedgehog promotes desmoplasia in pancreatic cancer.

    Jennifer M. Bailey;Benjamin J. Swanson;Tomofumi Hamada;John P. Eggers

  • MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer.

    Surendra K. Shukla;Vinee Purohit;Kamiya Mehla;Venugopal Gunda

  • Cell surface-associated mucins in signal transduction

    Pankaj K. Singh;Michael A. Hollingsworth

  • Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins.

    Jennifer M. Bailey;Pankaj K. Singh;Pankaj K. Singh;Michael A. Hollingsworth;Michael A. Hollingsworth

  • Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia

    Surendra K Shukla;Teklab Gebregiworgis;Vinee Purohit;Vinee Purohit;Nina V Chaika

  • MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer

    Nina V. Chaika;Teklab Gebregiworgis;Michelle E. Lewallen;Vinee Purohit

  • Graviola: A novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism

    María P. Torres;Satyanarayana Rachagani;Vinee Purohit;Poomy Pandey

  • Cytokines (IL-6, IL-8, TNF): early and reliable predictors of severe acute pancreatitis.

    Nakechand Pooran;Anant Indaram;Pankaj Singh;Simmy Bank

  • MUC4 Mucin Interacts with and Stabilizes the HER2 Oncoprotein in Human Pancreatic Cancer Cells

    Pallavi Chaturvedi;Ajay P. Singh;Subhankar Chakraborty;Subhash C. Chauhan

  • O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3.

    Xinghui Li;Wei Gong;Hao Wang;Tianliang Li

  • De Novo Lipid Synthesis Facilitates Gemcitabine Resistance through Endoplasmic Reticulum Stress in Pancreatic Cancer.

    Saber Tadros;Surendra K. Shukla;Ryan J. King;Venugopal Gunda

  • CRTC3 links catecholamine signalling to energy balance

    Youngsup Song;Judith Altarejos;Mark O. Goodarzi;Hiroshi Inoue

  • The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition

    Justin Goodwin;Michael L. Neugent;Shin Yup Lee;Shin Yup Lee;Joshua H. Choe

  • Targeting Hypoxia-Inducible Factor-1α/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis

    Justin Goodwin;Hyunsung Choi;Meng Hsiung Hsieh;Michael L. Neugent

  • Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer.

    V. Coothankandaswamy;S. Cao;Y. Xu;P. D. Prasad

  • RNA Interference Suppression of MUC1 Reduces the Growth Rate and Metastatic Phenotype of Human Pancreatic Cancer Cells

    Hideaki Tsutsumida;Benjamin J. Swanson;Pankaj K. Singh;Thomas C. Caffrey

  • Cyclin-Dependent Kinase 5 Is Amplified and Overexpressed in Pancreatic Cancer and Activated by Mutant K-Ras

    John P. Eggers;Paul M. Grandgenett;Eric C. Collisson;Michelle E. Lewallen

  • O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity.

    Tianliang Li;Xinghui Li;Kuldeep S. Attri;Changhong Liu

  • Erratum: MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer (Cancer Cell (2017) 32(1) (71–87.e7) (S1535610817302544) (10.1016/j.ccell.2017.06.004))

    Surendra K. Shukla;Vinee Purohit;Kamiya Mehla;Venugopal Gunda

Frequent Co-Authors

Michael A. Hollingsworth
Michael A. Hollingsworth University of Nebraska Medical Center
Robert Powers
Robert Powers University of Nebraska–Lincoln
John M. Asara
John M. Asara Beth Israel Deaconess Medical Center
Costas A. Lyssiotis
Costas A. Lyssiotis University of Michigan–Ann Arbor
Yu Lei
Yu Lei Sun Yat-sen University
Surinder K. Batra
Surinder K. Batra University of Nebraska Medical Center
Douglas R. Green
Douglas R. Green St. Jude Children's Research Hospital
Emanuel F. Petricoin
Emanuel F. Petricoin George Mason University
Paul R. Crocker
Paul R. Crocker University of Dundee

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