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Sandra J. Gendler

Sandra J. Gendler

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
22255
World Ranking
4320
National Ranking
2104

Research.com Recognitions

  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Sandra J. Gendler is affiliated with the Mayo Clinic in the United States. Their research spans multiple fields including Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine. Within these broad areas, they focus on subfields such as Immunology, Oncology, Molecular Biology, Biomedical Engineering, and Genetics.

The scientist's work addresses a range of topics, notably CAR-T cell therapy research, immunotherapy and immune responses, vaccines and immunoinformatics approaches, immune cell function and interaction, graphene and nanomaterials applications, RNA interference and gene delivery, and glycosylation and glycoproteins research.

Frequent co-authors in their published work include Latha Pathangey, D.S. Missan, Michael P. Gustafson, Marion Curtis, and G.A. Reckard. Their research has appeared in several publication venues with multiple contributions to Cancer Research and Cytotherapy, as well as publications in Oncotarget, Cancers, and Gynecologic Oncology.

Selected recent papers include:

  • Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma, 2021, Oncotarget
  • Prevention of Inflammation-Driven Colon Carcinogenesis in Human MUC1 Transgenic Mice by Vaccination with MUC1 DNA and Dendritic Cells, 2023, Cancers
  • Abstract A086: Rapid expansion of natural, MUC1-activated T cells from the peripheral blood of ovarian cancer patients for adoptive cell therapy, 2024, Cancer Research
  • Proteogenomics identifies immunogenic HLA-I cryptic peptides in ovarian cancer, 2024, Gynecologic Oncology
  • Abstract 6103: BCMA CAR engineering arms T cells with superior functions post ex vivo stimulation by MUC1 peptide-loaded autologous PBMCs, 2025, Cancer Research

Sandra J. Gendler has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2009.

Best Publications

  • Epithelial Mucin Genes

    Sandra J. Gendler;Andrew P. Spicer

  • Molecular cloning and expression of human Tumor-associated Polymorphic Epithelial Mucin

    S J Gendler;C A Lancaster;J Taylor-Papadimitriou;T Duhig

  • Structure and Function of the Cell Surface (Tethered) Mucins

    Christine L. Hattrup;Sandra J. Gendler

  • MUC1, the renaissance molecule.

    Sandra J. Gendler

  • A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats.

    Sandra Gendler;Joyce Taylor-Papadimitriou;Trevor Duhig;Jonathan Rothbard

  • Development and Characterization of Breast Cancer Reactive Monoclonal Antibodies Directed to the Core Protein of the Human Milk Mucin

    Joy Burchell;Sandra Gendler;Joyce Taylor-Papadimitriou;Anne Girling

  • Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland.

    Joyce A. Schroeder;Melissa C. Thompson;Melissa Mockensturm Gardner;Sandra J. Gendler

  • MUC1 cell surface mucin is a critical element of the mucosal barrier to infection

    Julie L. McAuley;Sara K. Linden;Chin Wen Png;Rebecca M. King

  • Abnormal heart rate regulation in GIRK4 knockout mice

    Kevin Wickman;Jan Nemec;Sandra J Gendler;David E Clapham

  • A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary carcinomas.

    Anne Girling;Jirina Bartkova;Joy Burchell;Sandra Gendler

  • Importance and regulation of the colonic mucus barrier in a mouse model of colitis

    Joel Petersson;Olof Schreiber;Gunnar C. Hansson;Sandra J. Gendler

  • Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine

    Vani Lakshminarayanan;Pamela Thompson;Margreet A. Wolfert;Therese Buskas

  • The human tumour-associated epithelial mucins are coded by an expressed hypervariable gene locus PUM

    Dallas M. Swallow;Sandra Gendler;Beatrice Griffiths;Gerald Corney

  • Delayed mammary tumor progression in Muc-1 null mice

    Andrew P. Spicer;Gerald J. Rowse;Thomas K. Lidner;Sandra J. Gendler

  • Expression and steroid hormonal control of muc-1 in the mouse uterus

    Gulnar A. Surveyor;Sandra J. Gendler;Lucy Pemberton;S. K. Das

  • Cloning of partial cDNA encoding differentiation and tumor-associated mucin glycoproteins expressed by human mammary epithelium

    S J Gendler;J M Burchell;T Duhig;D Lamport

  • The epithelial mucin, MUC1, of milk, mammary gland and other tissues

    Stuart Patton;Sandra J. Gendler;Andrew P. Spicer

  • Molecular cloning and analysis of the mouse homologue of the tumor-associated mucin, MUC1, reveals conservation of potential O-glycosylation sites, transmembrane, and cytoplasmic domains and a loss of minisatellite-like polymorphism.

    A.P. Spicer;G. Parry;S. Patton;S.J. Gendler

  • Reversal of tolerance to human MUC1 antigen in MUC1 transgenic mice immunized with fusions of dendritic and carcinoma cells

    Jianlin Gong;Dongshu Chen;Masahiro Kashiwaba;Yongqing Li

  • Tolerance and Immunity to MUC1 in a Human MUC1 Transgenic Murine Model

    Gerald J. Rowse;Richard M. Tempero;Michelle L. VanLith;Michael A. Hollingsworth

Frequent Co-Authors

Peter A. Cohen
Peter A. Cohen Mayo Clinic
Jianlin Gong
Jianlin Gong Boston University
Joyce Taylor-Papadimitriou
Joyce Taylor-Papadimitriou King's College London
Gunnar C. Hansson
Gunnar C. Hansson University of Gothenburg
Michael A. Hollingsworth
Michael A. Hollingsworth University of Nebraska Medical Center
Joy M. Burchell
Joy M. Burchell King's College London
Geert-Jan Boons
Geert-Jan Boons University of Georgia
Margreet A. Wolfert
Margreet A. Wolfert Utrecht University
Donald Kufe
Donald Kufe Harvard University
John C. Morris
John C. Morris Washington University in St. Louis

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