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Biology and Biochemistry

D-Index
69
Citations
18861
World Ranking
7320
National Ranking
566

Overview

Joy M. Burchell is affiliated with King's College London in the United Kingdom and has contributed extensively to research in biochemistry, genetics, molecular biology, immunology, microbiology, and medicine. Their work spans molecular biology, immunology, oncology, and organic chemistry, with a particular focus on immune cells in cancer and glycosylation-related processes.

The scientist's recent publications demonstrate a focus on cancer biology, immune regulation, glycoproteins, and molecular mechanisms underlying disease. Selected recent papers include:

  • "Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype" (2020, Communications Biology)
  • "LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer" (2023, Developmental Cell)
  • "Mucins and their receptors in chronic lung disease" (2020, Clinical & Translational Immunology)
  • "O-linked mucin-type glycosylation regulates the transcriptional programme downstream of EGFR" (2020, Glycobiology)
  • "Histone Methylases and Demethylases Regulating Antagonistic Methyl Marks: Changes Occurring in Cancer" (2022, Cells)

Frequent co-authors collaborating with Joy M. Burchell include:

  • Richard Beatson
  • Cheryl Gillett
  • Joyce Taylor-Papadimitriou
  • Rosalind Graham
  • Ester Pfeifer

The researcher commonly publishes in venues such as:

  • Cells
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Communications Biology
  • Developmental Cell
  • Clinical & Translational Immunology

Main research topics covered include:

  • Immune cells in cancer
  • Glycosylation and Glycoproteins Research
  • Phagocytosis and Immune Regulation
  • Cancer Immunotherapy and Biomarkers
  • Carbohydrate Chemistry and Synthesis
  • Galectins and Cancer Biology
  • RNA modifications and cancer

Best Publications

  • Molecular cloning and expression of human Tumor-associated Polymorphic Epithelial Mucin

    S J Gendler;C A Lancaster;J Taylor-Papadimitriou;T Duhig

  • Monoclonal antibodies to epithelium-specific components of the human milk fat globule membrane: production and reaction with cells in culture.

    Joyce Taylor-Papadimitriou;J. A. Peterson;J. Arklie;Joy Burchell

  • A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats.

    Sandra Gendler;Joyce Taylor-Papadimitriou;Trevor Duhig;Jonathan Rothbard

  • MUC1 and cancer

    J Taylor-Papadimitriou;J Burchell;D.W Miles;M Dalziel

  • Development and Characterization of Breast Cancer Reactive Monoclonal Antibodies Directed to the Core Protein of the Human Milk Mucin

    Joy Burchell;Sandra Gendler;Joyce Taylor-Papadimitriou;Anne Girling

  • Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

    Suzanne A. Eccles;Eric O. Aboagye;Simak Ali;Annie S. Anderson

  • Comparison of O-Linked Carbohydrate Chains in MUC-1 Mucin from Normal Breast Epithelial Cell Lines and Breast Carcinoma Cell Lines: DEMONSTRATION OF SIMPLER AND FEWER GLYCAN CHAINS IN TUMOR CELLS

    Kenneth O. Lloyd;Joy Burchell;Valery Kudryashov;Beatrice W.T. Yin

  • Mechanisms Underlying Aberrant Glycosylation of MUC1 Mucin in Breast Cancer Cells

    Inka Brockhausen;Ji-Mao Yang;Joy Burchell;Caroline Whitehouse

  • Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells

    Matthew J Grimshaw;Lucienne Cooper;Konstantinos Papazisis;Julia A Coleman

  • A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary carcinomas.

    Anne Girling;Jirina Bartkova;Joy Burchell;Sandra Gendler

  • Retargeting of human T cells to tumor-associated MUC1: the evolution of a chimeric antigen receptor.

    Scott Wilkie;Gianfranco Picco;Julie Foster;David M. Davies

  • Complexity of expression of antigenic determinants, recognized by monoclonal antibodies HMFG-1 and HMFG-2, in normal and malignant human mammary epithelial cells.

    J Burchell;H Durbin;J Taylor-Papadimitriou

  • The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9

    Richard Beatson;Virginia Tajadura-Ortega;Daniela Yordanova Achkova;Gianfranco Picco

  • Cloning of partial cDNA encoding differentiation and tumor-associated mucin glycoproteins expressed by human mammary epithelium

    S J Gendler;J M Burchell;T Duhig;D Lamport

  • Substrate Specificities of Three Members of the Human UDP-N-Acetyl-α-d-galactosamine:Polypeptide N-Acetylgalactosaminyltransferase Family, GalNAc-T1, -T2, and -T3

    Hans H. Wandall;Helle Hassan;Ekaterina Mirgorodskaya;Anne K. Kristensen

  • Cloning of a human UDP-N-acetyl-alpha-D-Galactosamine:polypeptide N-acetylgalactosaminyltransferase that complements other GalNAc-transferases in complete O-glycosylation of the MUC1 tandem repeat.

    Eric Paul Bennett;Helle Hassan;Ulla Mandel;Ekatarina Mirgorodskaya

  • Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.

    Anne Louise Sørensen;Celso A. Reis;Celso A. Reis;Mads A. Tarp;Ulla Mandel

  • Identification of a novel cancer-specific immunodominant glycopeptide epitope in the MUC1 tandem repeat.

    Mads A. Tarp;Anne Louise Sørensen;Ulla Mandel;Hans Paulsen

  • A short sequence, within the amino acid tandem repeat of a cancer-associated mucin, contains immunodominant epitopes.

    Joy Burchell;Joyce Taylor‐Papadimitriou;Martina Boshell;Sandra Gendler

  • O-linked glycosylation in the mammary gland: changes that occur during malignancy.

    Joy M. Burchell;Arron Mungul;Joyce Taylor-Papadimitriou

Frequent Co-Authors

Joyce Taylor-Papadimitriou
Joyce Taylor-Papadimitriou King's College London
Henrik Clausen
Henrik Clausen University of Copenhagen
Ulla Mandel
Ulla Mandel University of Copenhagen
Celso A. Reis
Celso A. Reis University of Porto
Eric P. Bennett
Eric P. Bennett University of Copenhagen
John Maher
John Maher King's College London
Michael A. Hollingsworth
Michael A. Hollingsworth University of Nebraska Medical Center
Sarah E Pinder
Sarah E Pinder King's College London
Hans H. Wandall
Hans H. Wandall University of Copenhagen

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