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Biology and Biochemistry

D-Index
55
Citations
10465
World Ranking
15097
National Ranking
168

Overview

Hans H. Wandall is affiliated with the University of Copenhagen in Denmark and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, with a strong focus on molecular biology, immunology, and oncology. Their research spans 61 publications in biochemistry, genetics, and molecular biology and 34 in medicine.

Their work often centers on specialized subfields including molecular biology, immunology, radiology, nuclear medicine, imaging, organic chemistry, and oncology. Key research topics associated with Wandall cover glycosylation and glycoproteins, galectins and cancer biology, monoclonal and polyclonal antibodies, carbohydrate chemistry and synthesis, CRISPR and genetic engineering, viral infectious diseases and gene expression in insects, as well as cancer, hypoxia, and metabolism.

Hans H. Wandall has authored or co-authored multiple scientific papers, reflecting a focus on glycosylation and its biological implications. Recent publications include:

  • Glycoproteomics, 2022, Nature Reviews Methods Primers
  • Global functions of O-glycosylation: promises and challenges in O-glycobiology, 2021, FEBS Journal
  • INDEL detection, the 'Achilles heel' of precise genome editing: a survey of methods for accurate profiling of gene editing induced indels, 2020, Nucleic Acids Research
  • Genetic glycoengineering in mammalian cells, 2021, Journal of Biological Chemistry
  • Site-Specific O-Glycosylation Analysis of SARS-CoV-2 Spike Protein Produced in Insect and Human Cells, 2021, Viruses

Frequent co-authors collaborating with Wandall include:

  • Sally Dabelsteen
  • Ieva Bagdonaite
  • Sergey Y. Vakhrushev
  • Mathias I. Nielsen
  • Noortje de Haan

Wandall's research has been published in several recurring scientific venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Advances in Experimental Medicine and Biology
  • Analytical Chemistry
  • Nature Communications

Best Publications

  • Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology

    Catharina Steentoft;Sergey Vakhrushev;Hiren Jitendra Joshi;Hiren Jitendra Joshi;Yun Kong

  • Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines

    Catharina Steentoft;Sergey Y Vakhrushev;Malene B Vester-Christensen;Katrine T-B G Schjoldager

  • Substrate Specificities of Three Members of the Human UDP-N-Acetyl-α-d-galactosamine:Polypeptide N-Acetylgalactosaminyltransferase Family, GalNAc-T1, -T2, and -T3

    Hans H. Wandall;Helle Hassan;Ekaterina Mirgorodskaya;Anne K. Kristensen

  • Immature truncated O-glycophenotype of cancer directly induces oncogenic features

    Prakash Radhakrishnan;Sally Dabelsteen;Frey Brus Madsen;Chiara Francavilla

  • Cancer Biomarkers Defined by Autoantibody Signatures to Aberrant O-Glycopeptide Epitopes

    Hans H. Wandall;Ola Blixt;Mads A. Tarp;Johannes W. Pedersen

  • Localization of three human polypeptide GalNAc-transferases in HeLa cells suggests initiation of O-linked glycosylation throughout the Golgi apparatus

    Sabine Röttger;Jamie White;Hans H. Wandall;Jean-Christophe Olivo

  • Role of sialic acid for platelet life span: exposure of β-galactose results in the rapid clearance of platelets from the circulation by asialoglycoprotein receptor–expressing liver macrophages and hepatocytes

    Anne Louise Sørensen;Anne Louise Sørensen;Viktoria Rumjantseva;Viktoria Rumjantseva;Sara Nayeb-Hashemi;Henrik Clausen

  • Dual roles for hepatic lectin receptors in the clearance of chilled platelets

    Viktoria Rumjantseva;Prabhjit K Grewal;Hans H Wandall;Emma C Josefsson;Emma C Josefsson

  • Engineered CHO cells for production of diverse, homogeneous glycoproteins.

    Zhang Yang;Shengjun Wang;Adnan Halim;Morten Alder Schulz

  • Global aspects of viral glycosylation.

    Ieva Bagdonaite;Hans H Wandall

  • Fast and sensitive detection of indels induced by precise gene targeting

    Zhang Yang;Catharina Steentoft;Camilla Hauge;Lars Hansen

  • Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium

    Hannah Barrow;Xiuli Guo;Hans H. Wandall;Johannes W. Pedersen

  • Aberrant Expression of Mucin Core Proteins and O-Linked Glycans Associated with Progression of Pancreatic Cancer

    Neeley Remmers;Judy M. Anderson;Erin M. Linde;Dominick J. DiMaio

  • Seromic profiling of colorectal cancer patients with novel glycopeptide microarray

    Johannes W. Pedersen;Ola Blixt;Eric P. Bennett;Mads A. Tarp

  • Characterizing the O-glycosylation landscape of human plasma, platelets, and endothelial cells.

    Sarah L. King;Hiren J. Joshi;Katrine T. Schjoldager;Adnan Halim

  • The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high density GalNAc-O-glycosylation

    Hans H. Wandall;Fernando Irazoqui;Fernando Irazoqui;Mads Agervig Tarp;Eric P. Bennett

  • Identification of a major human high molecular weight salivary mucin (MG1) as tracheobronchial mucin MUC5B

    Peter A. Nielsen;Eric P. Bennett;Hans H. Wandall;Marianne H. Therkildsen

  • Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells

    Katrine T.-B. G. Schjoldager;Sergey Y. Vakhrushev;Yun Kong;Catharina Steentoft

  • Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis

    Yun Kong;Hiren J. Joshi;Katrine Ter Borch Gram Schjoldager;Thomas Daugbjerg Madsen

  • Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents

    Sumeet A. Khetarpal;Katrine T. Schjoldager;Christina Christoffersen;Avanthi Raghavan

Frequent Co-Authors

Henrik Clausen
Henrik Clausen University of Copenhagen
Eric P. Bennett
Eric P. Bennett University of Copenhagen
Ulla Mandel
Ulla Mandel University of Copenhagen
John H. Hartwig
John H. Hartwig Brigham and Women's Hospital
Steven B. Levery
Steven B. Levery University of Copenhagen
Thomas P. Stossel
Thomas P. Stossel Brigham and Women's Hospital
Ola Blixt
Ola Blixt University of Copenhagen
Bent O. Petersen
Bent O. Petersen University of Copenhagen
Bernard Henrissat
Bernard Henrissat Technical University of Denmark
Joy M. Burchell
Joy M. Burchell King's College London

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