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Medicine

D-Index
97
Citations
47560
World Ranking
9110
National Ranking
4698

Overview

Michael A. Hollingsworth is affiliated with the University of Nebraska Medical Center in the United States. Their research spans multiple fields within medicine and biochemistry, genetics, and molecular biology, with a primary focus on oncology and cancer research.

The main fields of study for Hollingsworth include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Their work delves deeply into several subfields:

  • Oncology
  • Molecular Biology
  • Cancer Research
  • Immunology
  • Biotechnology

Hollingsworth has extensively explored diverse topics in cancer and related research areas, including:

  • Pancreatic and Hepatic Oncology Research
  • Cancer Research and Treatments
  • Cancer, Hypoxia, and Metabolism
  • Glycosylation and Glycoproteins Research
  • Cancer Cells and Metastasis
  • Radiomics and Machine Learning in Medical Imaging
  • Cancer Immunotherapy and Biomarkers

Their publication record includes numerous papers in prominent venues such as:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Cancers
  • Scientific Reports

Recent publications illustrate Hollingsworth's focus on cancer biology and metabolic dysfunction, including:

  • Tumour extracellular vesicles and particles induce liver metabolic dysfunction (2023, Nature)
  • Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix (2020, Journal of Clinical Investigation)
  • Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma (2020, Oncogene)
  • Predicted Prognosis of Patients with Pancreatic Cancer by Machine Learning (2020, Clinical Cancer Research)
  • SIRT1-NOX4 signaling axis regulates cancer cachexia (2020, The Journal of Experimental Medicine)

Collaboration is a significant aspect of Hollingsworth's research practice, with frequent coauthors including:

  • Paul M. Grandgenett
  • Thomas C. Caffrey
  • Prakash Radhakrishnan
  • Audrey J. Lazenby
  • Kelsey Klute

Best Publications

  • Tumour exosome integrins determine organotropic metastasis

    Ayuko Hoshino;Bruno Costa-Silva;Tang-Long Shen;Goncalo Rodrigues

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

    Bruno Costa-Silva;Nicole M. Aiello;Allyson J. Ocean;Swarnima Singh

  • Mucins in cancer: Protection and control of the cell surface

    Michael A. Hollingsworth;Benjamin J. Swanson

  • Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma

    Richard A. Moffitt;Raoud Marayati;Elizabeth L. Flate;Keith E. Volmar

  • Probiotics inhibit enteropathogenic E. coli adherence in vitro by inducing intestinal mucin gene expression.

    David R. Mack;Sonia Michail;Shu Wei;Laura McDougall

  • Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

    Ayuko Hoshino;Ayuko Hoshino;Han Sang Kim;Han Sang Kim;Linda Bojmar;Linda Bojmar;Linda Bojmar;Kofi Ennu Gyan

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Extracellular MUC3 mucin secretion follows adherence of Lactobacillus strains to intestinal epithelial cells in vitro.

    D R Mack;S Ahrne;L Hyde;S Wei

  • Organoid profiling identifies common responders to chemotherapy in pancreatic cancer

    Hervé Tiriac;Pascal Belleau;Dannielle D Engle;Dennis Plenker

  • Sonic hedgehog promotes desmoplasia in pancreatic cancer.

    Jennifer M. Bailey;Benjamin J. Swanson;Tomofumi Hamada;John P. Eggers

  • MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer.

    Surendra K. Shukla;Vinee Purohit;Kamiya Mehla;Venugopal Gunda

  • A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

    Faiyaz Notta;Michelle Chan-Seng-Yue;Mathieu Lemire;Yilong Li

  • Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs

    Eric Londina;Phillipe Lohera;Aristeidis G. Telonis;Kevin Quann

  • Highly Expressed Genes in Pancreatic Ductal Adenocarcinomas: A Comprehensive Characterization and Comparison of the Transcription Profiles Obtained from Three Major Technologies

    Christine A. Iacobuzio-Donahue;Raheela Ashfaq;Anirban Maitra;N. Volkan Adsay

  • Cell surface-associated mucins in signal transduction

    Pankaj K. Singh;Michael A. Hollingsworth

  • Discovery of Novel Tumor Markers of Pancreatic Cancer using Global Gene Expression Technology

    Christine A. Iacobuzio-Donahue;Anirban Maitra;Grace L. Shen-Ong;Tjarda van Heek

  • Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis

    Jae Seok Roe;Chang Il Hwang;Chang Il Hwang;Tim D.D. Somerville;Joseph P. Milazzo

  • Dystrophin glycoprotein complex dysfunction: a regulatory link between muscular dystrophy and cancer cachexia.

    Swarnali Acharyya;Matthew E.R. Butchbach;Zarife Sahenk;Huating Wang

  • Substrate Specificities of Three Members of the Human UDP-N-Acetyl-α-d-galactosamine:Polypeptide N-Acetylgalactosaminyltransferase Family, GalNAc-T1, -T2, and -T3

    Hans H. Wandall;Helle Hassan;Ekaterina Mirgorodskaya;Anne K. Kristensen

Frequent Co-Authors

Surinder K. Batra
Surinder K. Batra University of Nebraska Medical Center
Henrik Clausen
Henrik Clausen University of Copenhagen
Ann Harris
Ann Harris Case Western Reserve University
Eric P. Bennett
Eric P. Bennett University of Copenhagen
David A. Tuveson
David A. Tuveson Cold Spring Harbor Laboratory
Ralph H. Hruban
Ralph H. Hruban Johns Hopkins University School of Medicine
Ulla Mandel
Ulla Mandel University of Copenhagen
David R. Mack
David R. Mack University of Ottawa
Joy M. Burchell
Joy M. Burchell King's College London

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