World's Best Scientists 2026 revealed!
Isabelle Van Seuningen

Isabelle Van Seuningen

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
10885
World Ranking
13913
National Ranking
533

Overview

Isabelle Van Seuningen is affiliated with Inserm in France and has made contributions primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their research output includes a significant focus on Molecular Biology and Oncology, with additional emphasis on Cancer Research, Radiology, Nuclear Medicine and Imaging, and Nutrition and Dietetics.

The scientist's main research topics encompass:

  • Glycosylation and Glycoproteins Research
  • Pancreatic and Hepatic Oncology Research
  • Monoclonal and Polyclonal Antibodies Research
  • Cancer Genomics and Diagnostics
  • Cancer Cells and Metastasis
  • Magnesium in Health and Disease
  • Plant Micronutrient Interactions and Effects

Notable recent publications include:

  • Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer, 2020, Nature Medicine
  • Mg2+ Transporters in Digestive Cancers, 2021, Nutrients
  • Long non-coding RNAs: the tentacles of chromatin remodeler complexes, 2020, Cellular and Molecular Life Sciences
  • Galectin-3 modulates epithelial cell adaptation to stress at the ER-mitochondria interface, 2020, Cell Death and Disease
  • Cross-talk between YAP and RAR-RXR Drives Expression of Stemness Genes to Promote 5-FU Resistance and Self-Renewal in Colorectal Cancer Cells, 2021, Molecular Cancer Research

Frequent co-authors who have collaborated extensively with Isabelle Van Seuningen include:

  • Nicolas Jonckheere (23 publications)
  • Audrey Vincent (15 publications)
  • Bernadette Neve (10 publications)
  • Bélinda Duchêne (8 publications)
  • Maxime Liberelle (7 publications)

Key publication venues where this scientist's work appears frequently are:

  • Cancers (6 publications)
  • Cell Death and Disease (3 publications)
  • Cancer Research (3 publications)
  • Trends in Pharmacological Sciences (2 publications)
  • Cells (2 publications)

Best Publications

  • Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection

    Maria Van der Sluis;Barbara A.E. De Koning;Adrianus C.J.M. De Bruijn;Anna Velcich

  • The regulation of intestinal mucin MUC2 expression by short-chain fatty acids: implications for epithelial protection.

    Nanda Burger‑van Paassen;Audrey Vincent;Patrycja J. Puiman;Maria van der Sluis

  • Pattern of recurrence following complete resection of esophageal carcinoma and factors predictive of recurrent disease

    Christophe Mariette;Jean-Michel Balon;Guillaune Piessen;Sylvain Fabre

  • Induction of MUC2 and MUC5AC Mucins by Factors of the Epidermal Growth Factor (EGF) Family Is Mediated by EGF Receptor/Ras/Raf/Extracellular Signal-regulated Kinase Cascade and Sp1*

    Michaël Perrais;Pascal Pigny;Marie-Christine Copin;Jean-Pierre Aubert

  • Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis

    Yasmine Touil;Wassila Igoudjil;Matthieu Corvaisier;Anne-Frederique Dessein

  • Diverse molecular interactions of the hnRNP K protein

    Karol Bomsztyk;Isabelle Van Seuningen;Hideaki Suzuki;Oleg Denisenko

  • Factors affecting postoperative course and survival after en bloc resection for esophageal carcinoma.

    Christophe Mariette;Guillaume Taillier;Isabelle Van Seuningen;Jean-Pierre Triboulet

  • Human MUC2 mucin gene is transcriptionally regulated by Cdx homeodomain proteins in gastrointestinal carcinoma cell lines.

    Patrícia Mesquita;Nicolas Jonckheere;Raquel Almeida;Marie-Paule Ducourouble

  • Transcriptional regulation of the 11p15 mucin genes. Towards new biological tools in human therapy, in inflammatory diseases and cancer?

    Isabelle Van Seuningen

  • The K Protein Domain That Recruits the Interleukin 1-responsive K Protein Kinase Lies Adjacent to a Cluster of c-Src and Vav SH3-binding Sites IMPLICATIONS THAT K PROTEIN ACTS AS A DOCKING PLATFORM

    I Van Seuningen;J Ostrowski;X R Bustelo;P R Sleath

  • Genomic organization of the 3' region of the human mucin gene MUC5B.

    Jean-Luc Desseyn;Jean-Pierre Aubert;Isabelle Van Seuningen;Nicole Porchet

  • Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis

    Grégory Peignon;Aurélie Durand;Wulfran Cacheux;Olivier Ayrault

  • Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer

    Maria Paula Roberti;Maria Paula Roberti;Satoru Yonekura;Satoru Yonekura;Satoru Yonekura;Connie P. M. Duong;Connie P. M. Duong;Marion Picard;Marion Picard;Marion Picard

  • Mucin 16 (cancer antigen 125) expression in human tissues and cell lines and correlation with clinical outcome in adenocarcinomas of the pancreas, esophagus, stomach, and colon

    Mirte M. Streppel;Mirte M. Streppel;Audrey Vincent;Radha Mukherjee;Nathaniel R. Campbell

  • The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers.

    Nicolas Jonckheere;Isabelle Van Seuningen

  • MUC1, a New Hypoxia Inducible Factor Target Gene, Is an Actor in Clear Renal Cell Carcinoma Tumor Progression

    Sébastien Aubert;Sébastien Aubert;Valérie Fauquette;Brigitte Hémon;Réjane Lepoivre

  • Esophageal carcinoma: prognostic differences between squamous cell carcinoma and adenocarcinoma.

    Christophe Mariette;Laetitia Finzi;Guillaume Piessen;Isabelle Van Seuningen

  • Resistin-like molecule β regulates intestinal mucous secretion and curtails TNBS-induced colitis in mice

    Rim Belharbi Krimi;Rim Belharbi Krimi;Larissa Kotelevets;Larissa Kotelevets;Laurent Dubuquoy;Pascale Plaisancié;Pascale Plaisancié

  • Sequence of the 5′-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells

    Isabelle Van Seuningen;Michaël Perrais;Pascal Pigny;Nicole Porchet

  • Minireview Diverse molecular interactions of the hnRNP K protein

    Karol Bomsztyk;Isabelle Van Seuningen;Hideaki Suzuki;Oleg Denisenko

Frequent Co-Authors

Nicole Porchet
Nicole Porchet University of Lille
Johannes B. van Goudoever
Johannes B. van Goudoever University of Amsterdam
Christian Gespach
Christian Gespach Sorbonne University
Surinder K. Batra
Surinder K. Batra University of Nebraska Medical Center
Philippe Delannoy
Philippe Delannoy University of Lille
Kermit L. Carraway
Kermit L. Carraway University of California, Davis
Celso A. Reis
Celso A. Reis University of Porto
Mathias Chamaillard
Mathias Chamaillard University of Lille

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