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Chisa Shukunami

Chisa Shukunami

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
8815
World Ranking
14662
National Ranking
1041

Overview

Chisa Shukunami is a researcher affiliated with Hiroshima University in Japan. Their work spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with a particular focus on orthopedics and sports medicine. The subfields they contribute to include molecular biology, surgery, oncology, and cell biology.

The scientist's research topics concentrate primarily on tendon structure and treatment, covering 28 publications in this area. Other significant themes in their work include sports injuries and prevention, shoulder injury and treatment, muscle physiology and disorders, bone health and treatments, knee injuries and reconstruction techniques, and congenital heart defects research.

Shukunami has published extensively in a range of specialized venues. Frequent publication outlets for their work include:

  • Frontiers in Cell and Developmental Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS ONE
  • Development
  • Bone

Their recent papers demonstrate a focus on molecular and physiological aspects of musculoskeletal biology. Notable recent publications include:

  • The mechanosensitive ion channel PIEZO1 is expressed in tendons and regulates physical performance, 2022, Science Translational Medicine
  • Loss of tenomodulin expression is a risk factor for age-related intervertebral disc degeneration, 2020, Aging Cell
  • Role of Scx+/Sox9+ cells as potential progenitor cells for postnatal supraspinatus enthesis formation and healing after injury in mice, 2020, PLoS ONE
  • Deficiency of TMEM53 causes a previously unknown sclerosing bone disorder by dysregulation of BMP-SMAD signaling, 2021, Nature Communications
  • Tenogenic Induction From Induced Pluripotent Stem Cells Unveils the Trajectory Towards Tenocyte Differentiation, 2022, Frontiers in Cell and Developmental Biology

Frequent co-authors collaborating with Shukunami include Denitsa Docheva, Aki Takimoto, Shinsei Yambe, and Yuki Yoshimoto, with multiple joint works published.

Best Publications

  • Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor.

    Chisa Shukunami;Chohei Shigeno;Tadao Atsumi;Kiyoto Ishizeki

  • Scleraxis positively regulates the expression of tenomodulin, a differentiation marker of tenocytes

    Chisa Shukunami;Aki Takimoto;Miwa Oro;Yuji Hiraki

  • Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro.

    Chisa Shukunami;Kiyoto Ishizeki;Tadao Atsumi;Yoshiyuki Ohta

  • Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis.

    Ikuyo Kou;Yohei Takahashi;Todd A Johnson;Atsushi Takahashi

  • Scx+/Sox9+ progenitors contribute to the establishment of the junction between cartilage and tendon/ligament.

    Yuki Sugimoto;Aki Takimoto;Haruhiko Akiyama;Ralf Kist

  • Host defense against oral microbiota by bone-damaging T cells

    Masayuki Tsukasaki;Noriko Komatsu;Kazuki Nagashima;Takeshi Nitta

  • Periostin advances atherosclerotic and rheumatic cardiac valve degeneration by inducing angiogenesis and MMP production in humans and rodents

    Daihiko Hakuno;Naritaka Kimura;Masatoyo Yoshioka;Makio Mukai

  • Sequential progression of the differentiation program by bone morphogenetic protein-2 in chondrogenic cell line ATDC5.

    Chisa Shukunami;Yoshiyuki Ohta;Masayoshi Sakuda;Yuji Hiraki

  • Identification of Chondromodulin I as a Novel Endothelial Cell Growth Inhibitor PURIFICATION AND ITS LOCALIZATION IN THE AVASCULAR ZONE OF EPIPHYSEAL CARTILAGE

    Yuji Hiraki;Hiroyuki Inoue;Ken Ichi Iyama;Akihito Kamizono

  • Chondromodulin-I maintains cardiac valvular function by preventing angiogenesis

    Masatoyo Yoshioka;Shinsuke Yuasa;Keisuke Matsumura;Kensuke Kimura

  • Conversion of Human Bone Marrow-Derived Mesenchymal Stem Cells into Tendon Progenitor Cells by Ectopic Expression of Scleraxis

    Paolo Alberton;Cvetan Popov;Markus Prägert;Julia Kohler

  • Functional Analysis of Diastrophic Dysplasia Sulfate Transporter ITS INVOLVEMENT IN GROWTH REGULATION OF CHONDROCYTES MEDIATED BY SULFATED PROTEOGLYCANS

    Hideshi Satoh;Masakazu Susaki;Chisa Shukunami;Ken-ichi Iyama

  • Scleraxis is a transcriptional activator that regulates the expression of Tenomodulin, a marker of mature tenocytes and ligamentocytes

    Chisa Shukunami;Aki Takimoto;Yuriko Nishizaki;Yuki Yoshimoto

  • A Functional SNP in BNC2 Is Associated with Adolescent Idiopathic Scoliosis

    Yoji Ogura;Ikuyo Kou;Shigenori Miura;Atsushi Takahashi

  • Molecular Cloning of tenomodulin, a Novel Chondromodulin-I Related Gene

    Chisa Shukunami;Yusuke Oshima;Yuji Hiraki

  • FGF-2 Stimulates the Growth of Tenogenic Progenitor Cells to Facilitate the Generation of Tenomodulin-Positive Tenocytes in a Rat Rotator Cuff Healing Model.

    Takuya Tokunaga;Chisa Shukunami;Nobukazu Okamoto;Takuya Taniwaki

  • Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system

    Yuki Yoshimoto;Aki Takimoto;Hitomi Watanabe;Yuji Hiraki

  • Chondromodulin-I and tenomodulin: A new class of tissue-specific angiogenesis inhibitors found in hypovascular connective tissues

    Chisa Shukunami;Yusuke Oshima;Yusuke Oshima;Yuji Hiraki

  • Anti-angiogenic action of the C-terminal domain of tenomodulin that shares homology with chondromodulin-I.

    Yusuke Oshima;Koji Sato;Fumi Tashiro;Jun-ichi Miyazaki

  • Scleraxis and osterix antagonistically regulate tensile force-responsive remodeling of the periodontal ligament and alveolar bone

    Aki Takimoto;Masayoshi Kawatsu;Yuki Yoshimoto;Tadafumi Kawamoto

Frequent Co-Authors

Yuji Hiraki
Yuji Hiraki Kyoto University
Hiroshi Masuhara
Hiroshi Masuhara National Yang Ming Chiao Tung University
Fujio Suzuki
Fujio Suzuki Osaka University
Haruhiko Akiyama
Haruhiko Akiyama Gifu University
Keiichi Fukuda
Keiichi Fukuda Keio University
Yasunori Okada
Yasunori Okada Juntendo University
Aritoshi Iida
Aritoshi Iida Nippon Medical School
Takashi Nakamura
Takashi Nakamura Kyoto University

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