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Haruhiko Akiyama

Haruhiko Akiyama

D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
21788
World Ranking
5024
National Ranking
327

Overview

Haruhiko Akiyama is affiliated with Gifu University in Japan and has an extensive research output primarily in the field of Medicine, with a concentration on Surgery. Their work encompasses various subfields including Rheumatology, Molecular Biology, Rehabilitation, and Orthopedics and Sports Medicine.

The scientist's research topics focus on issues related to orthopedic surgery, rehabilitation, and joint treatments. Specific topics covered include:

  • Total Knee Arthroplasty Outcomes
  • Orthopedic Surgery and Rehabilitation
  • Knee Injuries and Reconstruction Techniques
  • Hip Disorders and Treatments
  • Osteoarthritis Treatment and Mechanisms
  • Orthopaedic Implants and Arthroplasty
  • Elbow and Forearm Trauma Treatment

Some of the recent papers connected to their field of expertise include:

  • High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer's and Non-Alzheimer's Disease Tauopathies, 2020, published in Neuron
  • Differential Chromatin Binding of the Lung Lineage Transcription Factor NKX2-1 Resolves Opposing Murine Alveolar Cell Fates In Vivo, 2021, published in Nature Communications
  • SOX9 Switch Links Regeneration to Fibrosis at the Single-Cell Level in Mammalian Kidneys, 2024, published in Science
  • Induced Pluripotent Stem Cell-Derived Tenocyte-Like Cells Promote the Regeneration of Injured Tendons in Mice, 2020, published in Scientific Reports
  • Periosteal Stem Cells Control Growth Plate Stem Cells During Postnatal Skeletal Growth, 2022, published in Nature Communications

Haruhiko Akiyama has collaborated frequently with several coauthors, including:

  • Shingo Komura, with 40 joint works
  • Kazu Matsumoto, with 38 joint works
  • Hiroyasu Ogawa, with 36 joint works
  • Akihiro Hirakawa, with 29 joint works
  • Tetsuya Shimokawa, with 18 joint works

The major venues where their research has been published include the following:

  • Research Square (Research Square) - 8 publications
  • bioRxiv (Cold Spring Harbor Laboratory) - 7 publications
  • Journal of Orthopaedic Science - 7 publications
  • Orthopaedics & Traumatology Surgery & Research - 6 publications
  • JBJS Case Connector - 6 publications

Best Publications

  • The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6

    Haruhiko Akiyama;Marie-Christine Chaboissier;James F. Martin;Andreas Schedl

  • Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine

    Kenichiro Furuyama;Yoshiya Kawaguchi;Haruhiko Akiyama;Masashi Horiguchi

  • Interactions between Sox9 and β-catenin control chondrocyte differentiation

    Haruhiko Akiyama;Jon P. Lyons;Yuko Mori-Akiyama;Xiaohong Yang

  • Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma

    Janel L. Kopp;Guido von Figura;Erin Mayes;Fen-Fen Liu

  • Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors

    Haruhiko Akiyama;Jung Eun Kim;Jung Eun Kim;Kazuhisa Nakashima;Gener Balmes

  • Dysbiosis and Staphylococcus aureus Colonization Drives Inflammation in Atopic Dermatitis.

    Tetsuro Kobayashi;Tetsuro Kobayashi;Martin Glatz;Keisuke Horiuchi;Hiroshi Kawasaki

  • Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest

    Yuko Mori-Akiyama;Haruhiko Akiyama;David H. Rowitch;Benoit de Crombrugghe

  • Adult Hepatocytes Are Generated by Self-Duplication Rather than Stem Cell Differentiation

    Kilangsungla Yanger;David Knigin;Yiwei Zong;Lara Maggs

  • Uncoupling Sonic hedgehog control of pattern and expansion of the developing limb bud.

    Jianjian Zhu;Eiichiro Nakamura;Minh-Thanh Nguyen;Xiaozhong Bao

  • Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa

    Haruhiko Akiyama;Marie Christine Chaboissier;Richard R. Behringer;David H. Rowitch

  • Control of chondrogenesis by the transcription factor Sox9.

    Haruhiko Akiyama

  • Tendon-bone attachment unit is formed modularly by a distinct pool of Scx- and Sox9-positive progenitors

    Einat Blitz;Amnon Sharir;Haruhiko Akiyama;Elazar Zelzer

  • Scx+/Sox9+ progenitors contribute to the establishment of the junction between cartilage and tendon/ligament.

    Yuki Sugimoto;Aki Takimoto;Haruhiko Akiyama;Ralf Kist

  • Contribution of Leydig and Sertoli cells to testosterone production in mouse fetal testes

    Yuichi Shima;Kanako Miyabayashi;Shogo Haraguchi;Tatsuhiko Arakawa

  • Sox9-expressing precursors are the cellular origin of the cruciate ligament of the knee joint and the limb tendons.

    Tsunemitsu Soeda;Jian Min Deng;Benoit de Crombrugghe;Richard R. Behringer

  • Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways

    Daisuke Ikegami;Haruhiko Akiyama;Akira Suzuki;Akira Suzuki;Takashi Nakamura

  • Unraveling the transcriptional regulatory machinery in chondrogenesis.

    Haruhiko Akiyama;Veronique M Lefebvre

  • Positive Regulation of Adult Bone Formation by Osteoblast-Specific Transcription Factor Osterix†‡

    Wook-Young Baek;Min-A Lee;Ji Won Jung;Shin-Yoon Kim;Shin-Yoon Kim

  • Mobilized Adult Pituitary Stem Cells Contribute to Endocrine Regeneration in Response to Physiological Demand

    Karine Rizzoti;Haruhiko Akiyama;Robin Lovell-Badge

  • Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian Kidney

    Sanjeev Kumar;Jing Liu;Paul Pang;A. Michaela Krautzberger

Frequent Co-Authors

Takashi Nakamura
Takashi Nakamura Kyoto University
Richard R. Behringer
Richard R. Behringer The University of Texas MD Anderson Cancer Center
Benoit de Crombrugghe
Benoit de Crombrugghe The University of Texas MD Anderson Cancer Center
Sakae Tanaka
Sakae Tanaka University of Tokyo
Chisa Shukunami
Chisa Shukunami Hiroshima University
Tadashi Kokubo
Tadashi Kokubo Chubu University
Junji Konishi
Junji Konishi Kyoto University
Yuji Hiraki
Yuji Hiraki Kyoto University
Hiroshi Kawaguchi
Hiroshi Kawaguchi University of Tokyo
Yasuhiro Yamada
Yasuhiro Yamada University of Tokyo

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