World's Best Scientists 2026 revealed!
Yuji Hiraki

Yuji Hiraki

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
8688
World Ranking
14672
National Ranking
1043

Overview

Yuji Hiraki is affiliated with Kyoto University in Japan, with a primary research focus in Medicine and its various subfields including Surgery, Gastroenterology, Pulmonary and Respiratory Medicine, Molecular Biology, and Orthopedics and Sports Medicine.

The scientist's research spans topics related to Esophageal and GI Pathology, Gastrointestinal Bleeding Diagnosis and Treatment, Gastric Cancer Management and Outcomes, Gastroesophageal Reflux and Treatments, Esophageal Cancer Research and Treatment, as well as Tendon Structure and Treatment, and Shoulder Injury and Treatment.

Yuji Hiraki has contributed to several recent papers, including:

  • Development of a gel dedicated to gel immersion endoscopy, 2021, Endoscopy International Open
  • Role of Scx+/Sox9+ cells as potential progenitor cells for postnatal supraspinatus enthesis formation and healing after injury in mice, 2020, PLoS ONE
  • Scleraxis upregulated by transforming growth factor-β1 signaling inhibits tension-induced osteoblast differentiation of priodontal ligament cells via ephrin A2, 2021, Bone
  • Chondromodulin is necessary for cartilage callus distraction in mice, 2023, PLoS ONE
  • Factors contributing to changes in viscosity and flow rate of a dedicated gel for gel immersion endoscopy, 2022, Endoscopy International Open

The scientist frequently publishes in venues such as Endoscopy International Open, PLoS ONE, Bone, Digestive Endoscopy, and the International Journal of Molecular Sciences.

Frequent collaborators include Tomonori Yano, Atsushi Ohata, Chisa Shukunami, Aki Takimoto, and Alan Kawarai Lefor.

Best Publications

  • Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor.

    Chisa Shukunami;Chohei Shigeno;Tadao Atsumi;Kiyoto Ishizeki

  • Scleraxis positively regulates the expression of tenomodulin, a differentiation marker of tenocytes

    Chisa Shukunami;Aki Takimoto;Miwa Oro;Yuji Hiraki

  • Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro.

    Chisa Shukunami;Kiyoto Ishizeki;Tadao Atsumi;Yoshiyuki Ohta

  • Growth factors rapidly induce expression of the glucose transporter gene.

    Y Hiraki;O M Rosen;M J Birnbaum

  • Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis.

    Ikuyo Kou;Yohei Takahashi;Todd A Johnson;Atsushi Takahashi

  • Periostin advances atherosclerotic and rheumatic cardiac valve degeneration by inducing angiogenesis and MMP production in humans and rodents

    Daihiko Hakuno;Naritaka Kimura;Masatoyo Yoshioka;Makio Mukai

  • Sequential progression of the differentiation program by bone morphogenetic protein-2 in chondrogenic cell line ATDC5.

    Chisa Shukunami;Yoshiyuki Ohta;Masayoshi Sakuda;Yuji Hiraki

  • Identification of Chondromodulin I as a Novel Endothelial Cell Growth Inhibitor PURIFICATION AND ITS LOCALIZATION IN THE AVASCULAR ZONE OF EPIPHYSEAL CARTILAGE

    Yuji Hiraki;Hiroyuki Inoue;Ken Ichi Iyama;Akihito Kamizono

  • Bone morphogenetic proteins (BMP-2 and BMP-3) promote growth and expression of the differentiated phenotype of rabbit chondrocytes and osteoblastic MC3T3-E1 cells in vitro.

    Yuji Hiraki;Hiroyuki Inoue;Chohei Shigeno;Yuji Sanma

  • Chondromodulin-I maintains cardiac valvular function by preventing angiogenesis

    Masatoyo Yoshioka;Shinsuke Yuasa;Keisuke Matsumura;Kensuke Kimura

  • Molecular cloning of a new class of cartilage-specific matrix, chondromodulin-I, which stimulates growth of cultured chondrocytes.

    Yuji Hiraki;Hideho Tanaka;Hiroyuki Inoue;Jun Kondo

  • Functional Analysis of Diastrophic Dysplasia Sulfate Transporter ITS INVOLVEMENT IN GROWTH REGULATION OF CHONDROCYTES MEDIATED BY SULFATED PROTEOGLYCANS

    Hideshi Satoh;Masakazu Susaki;Chisa Shukunami;Ken-ichi Iyama

  • Effect of transforming growth factor β on cell proliferation and glycosaminoglycan synthesis by rabbit growth-plate chondrocytes in culture

    Yuji Hiraki;Hiroyuki Inoue;Reiko Hirai;Yukio Kato

  • Stimulation of cartilage‐matrix proteoglycan synthesis by morphologically transformed chondrocytes grown in the presence of fibroblast growth factor and transforming growth factor‐beta

    Hiroyuki Inoue;Yukio Kato;Masahiro Iwamoto;Yuji Hiraki

  • Scleraxis is a transcriptional activator that regulates the expression of Tenomodulin, a marker of mature tenocytes and ligamentocytes

    Chisa Shukunami;Aki Takimoto;Yuriko Nishizaki;Yuki Yoshimoto

  • A Functional SNP in BNC2 Is Associated with Adolescent Idiopathic Scoliosis

    Yoji Ogura;Ikuyo Kou;Shigenori Miura;Atsushi Takahashi

  • Molecular Cloning of tenomodulin, a Novel Chondromodulin-I Related Gene

    Chisa Shukunami;Yusuke Oshima;Yuji Hiraki

  • Differential and Synergistic Actions of Somatomedin-Like Growth Factors, Fibroblast Growth Factor and Epidermal Growth Factor in Rabbit Costal Chondrocytes

    Yukio Kato;Yuji Hiraki;Hiroyuki Inoue;Masahiko Kinoshita

  • FGF-2 Stimulates the Growth of Tenogenic Progenitor Cells to Facilitate the Generation of Tenomodulin-Positive Tenocytes in a Rat Rotator Cuff Healing Model.

    Takuya Tokunaga;Chisa Shukunami;Nobukazu Okamoto;Takuya Taniwaki

  • Chondromodulin-I and tenomodulin: A new class of tissue-specific angiogenesis inhibitors found in hypovascular connective tissues

    Chisa Shukunami;Yusuke Oshima;Yusuke Oshima;Yuji Hiraki

Frequent Co-Authors

Chisa Shukunami
Chisa Shukunami Hiroshima University
Fujio Suzuki
Fujio Suzuki Osaka University
Keiichi Fukuda
Keiichi Fukuda Keio University
Masaharu Takigawa
Masaharu Takigawa Okayama University
Junji Konishi
Junji Konishi Kyoto University
Haruhiko Akiyama
Haruhiko Akiyama Gifu University
Yasunori Okada
Yasunori Okada Juntendo University
Hiroshi Masuhara
Hiroshi Masuhara National Yang Ming Chiao Tung University
Tsuyoshi Asahi
Tsuyoshi Asahi Ehime University
Takashi Nakamura
Takashi Nakamura Kyoto University

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