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Molecular Biology

D-Index
114
Citations
50101
World Ranking
319
National Ranking
192

Overview

Benoit de Crombrugghe was affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research mainly spanned the fields of biochemistry, genetics, and molecular biology, with a specific focus on molecular biology, oncology, and cancer research.

Their work frequently explored topics related to cancer-related gene regulation and molecular pathways, including NF-κB signaling pathways, bone metabolism and diseases, TGF-β signaling in diseases, as well as RNA research and splicing.

Among their recent publications were:

  • Wnt/ß-catenin-mediated p53 suppression is indispensable for osteogenesis of mesenchymal progenitor cells, 2021, published in Cell Death and Disease
  • Osteoblast-Specific Overexpression of Nucleolar Protein NO66/RIOX1 in Mouse Embryos Leads to Osteoporosis in Adult Mice, 2023, published in Journal of Osteoporosis

Their frequent co-authors included Xin Zhou, Allyson Beilter, Zhaohui Xu, Ruli Gao, and Shunbin Xiong. Their scholarly contributions appeared most often in the journals Cell Death and Disease and Journal of Osteoporosis.

Best Publications

  • The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation

    Kazuhisa Nakashima;Xin Zhou;Gary Kunkel;Zhaoping Zhang

  • Sox9 is required for cartilage formation.

    Weimin Bi;Jian Min Deng;Zhaoping Zhang;Richard R. Behringer

  • The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6

    Haruhiko Akiyama;Marie-Christine Chaboissier;James F. Martin;Andreas Schedl

  • Some recent advances in the chemistry and biology of transforming growth factor-beta.

    M B Sporn;A B Roberts;L M Wakefield;B de Crombrugghe

  • SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene.

    V Lefebvre;W Huang;V R Harley;P N Goodfellow

  • Evidence for two functional gal promoters in intact Escherichia coli cells.

    H Aiba;S Adhya;B de Crombrugghe

  • A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

    Véronique Lefebvre;Ping Li;Benoit de Crombrugghe

  • Interactions between Sox9 and β-catenin control chondrocyte differentiation

    Haruhiko Akiyama;Jon P. Lyons;Yuko Mori-Akiyama;Xiaohong Yang

  • Cyclic AMP receptor protein: role in transcription activation

    B de Crombrugghe;S Busby;H Buc

  • A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-β

    Pellegrino Rossi;Gerard Karsenty;Anita B. Roberts;Nanette S. Roche

  • The transcription factors L-Sox5 and Sox6 are essential for cartilage formation

    Patrick Smits;Ping Li;Jennifer Mandel;Zhaoping Zhang

  • The Family of Collagen Genes

    E Vuorio;B de Crombrugghe

  • Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis.

    Qi Zhao;Heidi Eberspaecher;Véronique Lefebvre;Benoit de Crombrugghe

  • Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors

    Haruhiko Akiyama;Jung Eun Kim;Jung Eun Kim;Kazuhisa Nakashima;Gener Balmes

  • Regulatory mechanisms in the pathways of cartilage and bone formation.

    Benoit de Crombrugghe;Véronique Lefebvre;Kazuhisa Nakashima

  • Transcriptional mechanisms in osteoblast differentiation and bone formation

    Kazuhisa Nakashima;Benoit de Crombrugghe

  • Transcriptional mechanisms of chondrocyte differentiation

    Benoit de Crombrugghe;Veronique Lefebvre;Richard R. Behringer;Weimin Bi

  • NFAT and Osterix cooperatively regulate bone formation

    Takako Koga;Yuichi Matsui;Masataka Asagiri;Tatsuhiko Kodama

  • Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest

    Yuko Mori-Akiyama;Haruhiko Akiyama;David H. Rowitch;Benoit de Crombrugghe

  • Chondrocytes transdifferentiate into osteoblasts in endochondral bone during development, postnatal growth and fracture healing in mice.

    Xin Zhou;Klaus von der Mark;Stephen Henry;William Norton

Frequent Co-Authors

Richard R. Behringer
Richard R. Behringer The University of Texas MD Anderson Cancer Center
Haruhiko Akiyama
Haruhiko Akiyama Gifu University
Ira Pastan
Ira Pastan Center for Cancer Research
Klaus von der Mark
Klaus von der Mark University of Erlangen-Nuremberg
Takashi Nakamura
Takashi Nakamura Kyoto University
Amjad Javed
Amjad Javed University of Alabama at Birmingham
Di Chen
Di Chen Chinese Academy of Sciences
Masaharu Takigawa
Masaharu Takigawa Okayama University
Satrajit Sinha
Satrajit Sinha University at Buffalo, State University of New York
James F. Martin
James F. Martin Baylor College of Medicine

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