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Molecular Biology

D-Index
46
Citations
7781
World Ranking
2810
National Ranking
1349

Overview

Satrajit Sinha is affiliated with the University at Buffalo, State University of New York in the United States. Their research spans several interconnected areas primarily within biochemistry, genetics, molecular biology, medicine, and immunology and microbiology. The scientist's work frequently addresses molecular and cellular mechanisms underlying disease processes, with a notable focus on cancer and immunological disorders.

Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Immunology and Microbiology

Within these disciplines, the subfields of molecular biology, immunology, cancer research, physiology, and oncology have been prominent in their scientific output.

The core topics of their research work cover:

  • Salivary Gland Disorders and Functions
  • RNA modifications and cancer
  • T-cell and B-cell Immunology
  • RNA Research and Splicing
  • Cancer-related molecular mechanisms research
  • Cancer-related Molecular Pathways
  • Cancer, Hypoxia, and Metabolism

Sinha has published articles in several scientific journals. The most frequent publication venues include:

  • The Journal of Immunology
  • Frontiers in Immunology
  • Journal of Dental Research
  • Nature Cell Biology
  • iScience

Among recent papers authored or co-authored by Sinha are:

  • "Loss of ELF5-FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling" (2020, Nature Cell Biology)
  • "Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer" (2024, Cancer Cell)
  • "ΔNp63 is a pioneer factor that binds inaccessible chromatin and elicits chromatin remodeling" (2021, Epigenetics & Chromatin)
  • "Transcriptomic and Network Analysis of Minor Salivary Glands of Patients With Primary Sjögren's Syndrome" (2021, Frontiers in Immunology)
  • "Transcriptomic and Single-Cell Analysis Reveals Regulatory Networks and Cellular Heterogeneity in Mouse Primary Sjögren's Syndrome Salivary Glands" (2021, Frontiers in Immunology)

Frequent co-authors collaborating with Sinha include:

  • Rose-Anne Romano
  • Akinsola Oyelakin
  • Jonathan Bard
  • Christian Gluck
  • Lee Ann Garrett-Sinha

Best Publications

  • Elf5 inhibits the epithelial–mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2

    Rumela Chakrabarti;Rumela Chakrabarti;Julie Hwang;Mario Andres Blanco;Yong Wei

  • ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation

    Rose-Anne Romano;Kirsten Smalley;Caitlin Magraw;Vanida Ann Serna

  • TAp63 Prevents Premature Aging by Promoting Adult Stem Cell Maintenance

    Xiaohua Su;Maryline Paris;Young Jin Gi;Kenneth Y. Tsai

  • ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling

    Rumela Chakrabarti;Yong Wei;Julie Hwang;Xiang Hang

  • Determination of functional domains in the C subunit of the CCAAT-binding factor (CBF) necessary for formation of a CBF-DNA complex: CBF-B interacts simultaneously with both the CBF-A and CBF-C subunits to form a heterotrimeric CBF molecule.

    I S Kim;S Sinha;B de Crombrugghe;S N Maity

  • Three Classes of Mutations in the A Subunit of the CCAAT-Binding Factor CBF Delineate Functional Domains Involved in the Three-Step Assembly of the CBF-DNA Complex

    Satrajit Sinha;In-San Kim;K.-Y. Sohn;B. De Crombrugghe

  • An Active Role of the ΔN Isoform of p63 in Regulating Basal Keratin Genes K5 and K14 and Directing Epidermal Cell Fate

    Rose-Anne Romano;Kori Ortt;Barbara Birkaya;Kirsten Smalley

  • An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes.

    V Lefebvre;G Zhou;K Mukhopadhyay;C N Smith

  • Elf5 conditional knockout mice reveal its role as a master regulator in mammary alveolar development: failure of Stat5 activation and functional differentiation in the absence of Elf5.

    Yeon Sook Choi;Rumela Chakrabarti;Rosalba Escamilla-Hernandez;Satrajit Sinha

  • IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis.

    Heather R. Conti;Heather R. Conti;Vincent M. Bruno;Erin E. Childs;Sean Daugherty

  • Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response

    Ali R. Djalilian;David McGaughey;Satyakam Patel;Eun Young Seo

  • Elf5 regulates mammary gland stem/progenitor cell fate by influencing notch signaling.

    Rumela Chakrabarti;Rumela Chakrabarti;Yong Wei;Rose Anne Romano;Christina DeCoste

  • Three different polypeptides are necessary for DNA binding of the mammalian heteromeric CCAAT binding factor.

    S N Maity;S Sinha;E C Ruteshouser;B de Crombrugghe

  • Physiological Control of Smooth Muscle-specific Gene Expression through Regulated Nuclear Translocation of Serum Response Factor

    Blanca Camoretti-Mercado;Hong Wei Liu;Andrew J. Halayko;Sean M. Forsythe

  • The Transcription Factor Encyclopedia

    Dimas Yusuf;Stefanie L. Butland;Magdalena I. Swanson;Eugene I. Bolotin

  • A Functional Enhancer of Keratin14 Is a Direct Transcriptional Target of ΔNp63

    Rose-Anne Romano;Barbara Birkaya;Satrajit Sinha

  • Rescue of platinum-damaged oocytes from programmed cell death through inactivation of the p53 family signaling network

    S. Y. Kim;M. H. Cordeiro;V. A. Serna;K. Ebbert

  • Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells.

    Briana Lee;Alvaro Villarreal-Ponce;Magid Fallahi;Jeremy Ovadia

  • Defining the Regulatory Factors Required for Epidermal Gene Expression

    Satrajit Sinha;Linda Degenstein;Cedith Copenhaver;Elaine Fuchs

  • The Transcriptional Activity of the CCAAT-binding Factor CBF Is Mediated by Two Distinct Activation Domains, One in the CBF-B Subunit and the Other in the CBF-C Subunit

    Françoise Coustry;Sankar N. Maity;Satrajit Sinha;Benoit de Crombrugghe

Frequent Co-Authors

Susanne Mandrup
Susanne Mandrup University of Southern Denmark
Sekhar P. Reddy
Sekhar P. Reddy University of Illinois at Chicago
Kathleen J. Millen
Kathleen J. Millen Seattle Children's Hospital
Robert F. Hevner
Robert F. Hevner University of California, San Diego
Paola Bovolenta
Paola Bovolenta Spanish National Research Council
Bruce E. Torbett
Bruce E. Torbett Seattle Children's Hospital
Elizabeth M. Simpson
Elizabeth M. Simpson University of British Columbia
Wyeth W. Wasserman
Wyeth W. Wasserman University of British Columbia
Reiner A. Veitia
Reiner A. Veitia Université Paris Cité
Peggy J. Farnham
Peggy J. Farnham University of Southern California

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