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Biology and Biochemistry

D-Index
61
Citations
17706
World Ranking
11175
National Ranking
4838

Overview

Sekhar P. Reddy is affiliated with the University of Illinois at Chicago in the United States. Their research spans multiple fields primarily focused on medicine and immunology and microbiology, with significant contributions in related subfields such as immunology, pulmonary and respiratory medicine, molecular biology, physiology, and genetics.

Their work encompasses a range of main topics that include:

  • Phagocytosis and Immune Regulation
  • Immune cells in cancer
  • Respiratory Support and Mechanisms
  • Neonatal Respiratory Health Research
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Dietary Effects on Health
  • Congenital Diaphragmatic Hernia Studies

Sekhar P. Reddy has published extensively in scientific venues, with frequent appearances in:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Antioxidants
  • Scientific Reports
  • American Journal of Physiology-Renal Physiology
  • Nature Biomedical Engineering

Recent published papers by Sekhar P. Reddy include:

  • "Nrf2 mediates hypoxia-inducible HIF1α activation in kidney tubular epithelial cells" (2021, American Journal of Physiology-Renal Physiology)
  • "Inhibition of aberrant tissue remodelling by mesenchymal stromal cells singly coated with soft gels presenting defined chemomechanical cues" (2021, Nature Biomedical Engineering)
  • "Lysocardiolipin acyltransferase regulates NSCLC cell proliferation and migration by modulating mitochondrial dynamics" (2020, Journal of Biological Chemistry)
  • "Preconditioning the immature lung with enhanced Nrf2 activity protects against oxidant-induced hypoalveolarization in mice" (2020, Scientific Reports)
  • "Recent advances in dead cell clearance during acute lung injury and repair" (2021, Faculty Reviews)

Collaborations are evident in their frequent co-authors, including:

  • Aparna Ankireddy
  • Patrick Noone
  • Chandra Mohan Tamatam
  • Haranatha R. Potteti
  • Chandramohan R. Tamatam

The body of research conducted by Sekhar P. Reddy reveals an interdisciplinary approach integrating elements of immunology, respiratory medicine, and molecular biology. The scientist has contributed to understanding mechanisms at cellular and molecular levels, especially related to immune regulation, lung health, and cancer biology.

Best Publications

  • Reactive Oxygen Species in Inflammation and Tissue Injury

    Manish Mittal;Mohammad Rizwan Siddiqui;Khiem Tran;Sekhar P. Reddy

  • Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

    Rajesh K. Thimmulappa;Hannah Lee;Tirumalai Rangasamy;Sekhar P. Reddy

  • Role of NRF2 in protection against hyperoxic lung injury in mice

    Hye Youn Cho;Anne E. Jedlicka;Sekhar P.M. Reddy;Thomas W. Kensler

  • Nrf2 defends the lung from oxidative stress.

    Hye-Youn Cho;Sekhar P. Reddy;Steven R. Kleeberger

  • Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury

    Jacqui M. Marzec;Jason D. Christie;Sekhar P. Reddy;Anne E. Jedlicka

  • The transcription factor NRF2 protects against pulmonary fibrosis

    Hye-Youn Cho;Hye-Youn Cho;Sekhar P. M. Reddy;Masayuki Yamamoto;Steven R. Kleeberger;Steven R. Kleeberger

  • Gene expression profiling of NRF2-mediated protection against oxidative injury.

    Hye-Youn Cho;Sekhar P. Reddy;Andrea DeBiase;Masayuki Yamamoto

  • Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice

    Manchang Liu;Dmitry N. Grigoryev;Michael T. Crow;Mark Haas

  • Hyperoxia Stimulates an Nrf2-ARE Transcriptional Response via ROS-EGFR-PI3K-Akt/ERK MAP Kinase Signaling in Pulmonary Epithelial Cells

    Srinivas Papaiahgari;Qin Zhang;Steven R. Kleeberger;Hye-Youn Cho

  • Enhancing Nrf2 Pathway by Disruption of Keap1 in Myeloid Leukocytes Protects against Sepsis

    Xiaoni Kong;Rajesh Thimmulappa;Florin Craciun;Christopher Harvey

  • Nrf2-regulated PPARγ Expression Is Critical to Protection against Acute Lung Injury in Mice

    Hye Youn Cho;Wesley Gladwell;Xuting Wang;Brian Chorley

  • Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2.

    Melanie Theodore;Yumiko Kawai;Jianqi Yang;Yuliya Kleshchenko

  • Oxidants and signaling by mitogen-activated protein kinases in lung epithelium.

    Brooke T. Mossman;Karen M. Lounsbury;Sekhar P. Reddy

  • Linkage analysis of susceptibility to hyperoxia. Nrf2 is a candidate gene

    Hye-Youn Cho;Anne E. Jedlicka;Sekhar P. M. Reddy;Liu-Yi Zhang

  • ERK1 and ERK2 Activate CCAAAT/Enhancer-binding Protein-β-dependent Gene Transcription in Response to Interferon-γ

    Junbo Hu;Sanjit K. Roy;Paul S. Shapiro;Scott R. Rodig

  • Genetic susceptibility to ozone-induced lung hyperpermeability: role of toll-like receptor 4.

    Steven R. Kleeberger;Sekhar Reddy;Liu Yi Zhang;Anne E. Jedlicka

  • NADPH oxidase and ERK signaling regulates hyperoxia-induced Nrf2-ARE transcriptional response in pulmonary epithelial cells

    Srinivas Papaiahgari;Steven R. Kleeberger;Hye-Youn Cho;Dhananjaya V. Kalvakolanu

  • Role and regulation of activator protein-1 in toxicant-induced responses of the lung.

    Sekhar P. M. Reddy;Brooke T. Mossman

  • Disruption of Nrf2 Impairs the Resolution of Hyperoxia-Induced Acute Lung Injury and Inflammation in Mice

    Narsa M. Reddy;Steven R. Kleeberger;Thomas W. Kensler;Masayuki Yamamoto

  • Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2. VOLUME 283 (2008) PAGES 8984-8994

    Melanie Theodore;Yumiko Kawai;Jianqi Yang;Yuliya Kleshchenko

Frequent Co-Authors

Dhananjaya V. Kalvakolanu
Dhananjaya V. Kalvakolanu University of Maryland, Baltimore
Steven R. Kleeberger
Steven R. Kleeberger National Institutes of Health
Paul M. Hassoun
Paul M. Hassoun Johns Hopkins University
Masayuki Yamamoto
Masayuki Yamamoto Tohoku University
Shyam Biswal
Shyam Biswal Johns Hopkins University
Viswanathan Natarajan
Viswanathan Natarajan University of Illinois at Chicago
Thomas W. Kensler
Thomas W. Kensler Johns Hopkins University
Joe G.N. Garcia
Joe G.N. Garcia University of Arizona
Hamid Rabb
Hamid Rabb Johns Hopkins University
Reen Wu
Reen Wu University of California, Davis

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