2026 Age K. Smilde: Engineering and Technology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Engineering and Technology	77	634	601	14	12	302	31489

Overview

Age K. Smilde is a researcher affiliated with the University of Amsterdam in the Netherlands. Their research contributions span several interdisciplinary fields, including biochemistry, genetics, and molecular biology, with a notable focus on molecular biology within these domains. Their academic work integrates computational mathematics and analytical chemistry, extending also into plant science and epidemiology.

Their research covers a range of topics. Notably, they have contributed extensively to metabolomics and mass spectrometry studies. Additional focal areas include tensor decomposition and applications, gene expression and cancer classification, spectroscopy and chemometric analyses, bioinformatics and genomic networks, gut microbiota and health, and mental health research topics.

Age K. Smilde has published in various scientific venues, with frequent contributions to the Journal of Chemometrics, bioRxiv (Cold Spring Harbor Laboratory), Scientific Reports, PLoS Computational Biology, and Chemometrics and Intelligent Laboratory Systems.

Key recent papers authored or co-authored by Smilde illustrate the diversity and scope of their work:

"Corruption of the Pearson correlation coefficient by measurement error and its estimation, bias, and correction under different error models," 2020, Scientific Reports
"Effect of strigolactones on recruitment of the rice root-associated microbiome," 2022, FEMS Microbiology Ecology
"Transcriptional profiles of adjuvanted hepatitis B vaccines display variable interindividual homogeneity but a shared core signature," 2020, Science Translational Medicine
"Increased comparability between RNA-Seq and microarray data by utilization of gene sets," 2020, PLoS Computational Biology
"Revealing hidden information in GC-MS spectra from isomeric drugs: Chemometrics based identification from 15 eV and 70 eV EI mass spectra," 2020, Forensic Chemistry

Their collaboration network includes several frequent co-authors with whom they have worked extensively:

Johan A. Westerhuis
Bruce R. Kowalski
Paul Trevorrow
Janine Maer
Dela Torre

Best Publications

Principal component analysis

Rasmus Bro;Age K. Smilde;Age K. Smilde

3202
Citations
Centering, scaling, and transformations: improving the biological information content of metabolomics data

Robert A van den Berg;Huub C J Hoefsloot;Johan A Westerhuis;Age K Smilde

2741
Citations
Assessment of PLSDA cross validation

Johan A. Westerhuis;Huub C. J. Hoefsloot;Suzanne Smit;Daniel J. Vis

1589
Citations
Multi-way Analysis: Applications in the Chemical Sciences

Age K Smilde;Rasmus Bro;Paul Geladi

1520
Citations
Selectivity, local rank, three‐way data analysis and ambiguity in multivariate curve resolution

Romà Tauler;Age Smilde;Bruce Kowalski

1101
Citations
Large-scale human metabolomics studies: a strategy for data (pre-) processing and validation.

Sabina Bijlsma;Ivana Bobeldijk;Elwin R Verheij;Raymond Ramaker

973
Citations
Double-check: validation of diagnostic statistics for PLS-DA models in metabolomics studies.

Ewa Szymańska;Edoardo Saccenti;Age K. Smilde;Johan A. Westerhuis

930
Citations
Multi-Way Analysis with Applications in the Chemical Sciences: Smilde/Multi-Way Analysis with Applications in the Chemical Sciences

Age Smilde;Rasmus Bro;Paul Geladi

791
Citations
ANOVA-simultaneous component analysis (ASCA): a new tool for analyzing designed metabolomics data

Age K. Smilde;Jeroen J. Jansen;Huub C. J. Hoefsloot;Robert-Jan A. N. Lamers

713
Citations
Reflections on univariate and multivariate analysis of metabolomics data

Edoardo Saccenti;Huub C. J. Hoefsloot;Age K. Smilde;Johan A. Westerhuis

652
Citations
Generalized contribution plots in multivariate statistical process monitoring

Johan A. Westerhuis;Stephen P. Gurden;Age K. Smilde

615
Citations
Metabolic fate of polyphenols in the human superorganism

John van Duynhoven;Elaine E. Vaughan;Doris M. Jacobs;Robèr A. Kemperman

614
Citations
Centering and scaling in component analysis

Rasmus Bro;Age K. Smilde

555
Citations
Proposed minimum reporting standards for data analysis in metabolomics

Royston Goodacre;David Broadhurst;Age K. Smilde;Bruce S. Kristal

515
Citations
Multivariate paired data analysis: multilevel PLSDA versus OPLSDA

Johan A. Westerhuis;Ewoud J. J. van Velzen;Huub C. J. Hoefsloot;Age K. Smilde

456
Citations
Direct orthogonal signal correction

Johan A. Westerhuis;Sijmen de Jong;Age K. Smilde

403
Citations
Cross-validation of component models: A critical look at current methods

R. Bro;K. Kjeldahl;A. K. Smilde;H. A. L. Kiers

398
Citations
Fusion of mass spectrometry-based metabolomics data.

Age K Smilde;Mariët J van der Werf;Sabina Bijlsma;Bianca J C van der Werff-van der Vat

372
Citations
Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis

Robert Kleemann;Lars Verschuren;Marjan J van Erk;Yuri Nikolsky

288
Citations
Influence of Temperature on Vibrational Spectra and Consequences for the Predictive Ability of Multivariate Models

Florian Wülfert;Wim Th. Kok;Age K. Smilde

287
Citations
Chemometrics and Intelligent Laboratory Systems

Iven Van Mechelen;Age K. Smilde

0
Citations