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Biology and Biochemistry

D-Index
57
Citations
12588
World Ranking
13768
National Ranking
1077

Overview

Nullin Divecha is affiliated with the University of Southampton in the United Kingdom, focusing primarily on research in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields including Molecular Biology, Cell Biology, Immunology, Infectious Diseases, and Pulmonary and Respiratory Medicine.

The scientist's research topics include:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Cellular transport and secretion
  • Protein Kinase Regulation and GTPase Signaling
  • Hippo pathway signaling and YAP/TAZ
  • Microtubule and mitosis dynamics
  • Cellular Mechanics and Interactions

Nullin Divecha has published several papers in notable scientific venues. Some recent publications include:

  • "PIP4Ks impact on PI3K, FOXP3, and UHRF1 signaling and modulate human regulatory T cell proliferation and immunosuppressive activity," 2021, Proceedings of the National Academy of Sciences
  • "Nuclear Phosphoinositides as Key Determinants of Nuclear Functions," 2023, Biomolecules
  • "PIP4K2B is mechanoresponsive and controls heterochromatin-driven nuclear softening through UHRF1," 2023, Nature Communications
  • "Mechanisms of SARS-CoV-2 Inactivation Using UVC Laser Radiation," 2023, ACS Photonics
  • "Identification and optimization of a novel series of selective PIP5K inhibitors," 2021, Bioorganic & Medicinal Chemistry

The scientist frequently collaborates with other researchers, with coauthor counts reflecting ongoing partnerships. Frequent coauthors include:

  • Bhavwanti Sheth
  • Roberta Fiume
  • Alessandro Poli
  • Magdalena Castellano Vidalle
  • Stefano Ratti

Nullin Divecha's work regularly appears in several scientific venues, with multiple publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Biomolecules
  • Nature Communications
  • ACS Photonics

Best Publications

  • Mammalian SIRT1 Represses Forkhead Transcription Factors

    Maria Carla Motta;Nullin Divecha;Madeleine Lemieux;Christopher Kamel

  • DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

    Katharine O Hartley;David Gell;Graeme C.M Smith;Hong Zhang

  • The PHD Finger of the Chromatin-Associated Protein ING2 Functions as a Nuclear Phosphoinositide Receptor

    Or Gozani;Philip Karuman;David R. Jones;Dmitri Ivanov

  • The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase C to the nucleus.

    N Divecha;H Banfić;R F Irvine

  • PIP5K-driven PtdIns(4,5)P2 synthesis: regulation and cellular functions

    Iman van den Bout;Nullin Divecha

  • Multivesicular body morphogenesis requires phosphatidyl-inositol 3-kinase activity.

    Mar Fernandez-Borja;Richard Wubbolts;Jero Calafat;Hans Janssen

  • Inositides and the nucleus and inositides in the nucleus

    Nullin Divecha;Hrvoje Banfić;Robin F. Irvine

  • Evaluation and Optimization of ZIC-HILIC-RP as an Alternative MudPIT Strategy

    Paul J. Boersema;Nullin Divecha;Albert J. R. Heck;Shabaz Mohammed

  • Visualization of PtdIns3P dynamics in living plant cells

    Joop E.M. Vermeer;Wessel van Leeuwen;Rafa Tobeña-Santamaria;Ana M. Laxalt

  • Phosphoinositide signalling enzymes in rat liver nuclei: phosphoinositidase C isoform β1 is specifically, but not predominantly, located in the nucleus

    N. Divecha;Sue-Goo Rhee;A. J. Letcher;R. F. Irvine

  • Phospholipid signalling in the nucleus. Een DAG uit het leven van de inositide signalering in de nucleus.

    C.S. D’Santos;J.H. Clarke;N. Divecha

  • Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4Kbeta.

    David R. Jones;Yvette Bultsma;Willem Jan Keune;Jonathan R. Halstead

  • Inositol lipids are regulated during cell cycle progression in the nuclei of murine erythroleukaemia cells.

    Jonathan H. Clarke;Jonathan H. Clarke;Andrew J. Letcher;Clive S. D'santos;Jonathan R. Halstead

  • The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-beta/Smad signalling.

    Fumiko Itoh;Nullin Divecha;Lenny Brocks;Lauran Oomen

  • Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis

    Sergey Lekomtsev;Kuan Chung Su;Valerie E. Pye;Ken Blight

  • Interaction of the Type Iα PIPkinase with phospholipase D: a role for the local generation of phosphatidylinositol 4,5-bisphosphate in the regulation of PLD2 activity

    Nullin Divecha;Mieke Roefs;Jonathan R. Halstead;Sabine D'Andrea

  • Metabolism and possible compartmentalization of inositol lipids in isolated rat-liver nuclei

    L. R. Vann;F. B. P. Wooding;R. F. Irvine;N. Divecha

  • Hyperosmotic stress induces rapid synthesis of phosphatidyl-D-inositol 3,5-bisphosphate in plant cells

    H.J.G. Meijer;N. Divecha;H. van den Ende;A. Musgrave

  • Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm.

    David Weinkove;David Weinkove;Jonathan R Halstead;David Gems;Nullin Divecha

  • Nuclear diacylglycerol is increased during cell proliferation in vivo

    H Banfić;M Zizak;N Divecha;R F Irvine

Frequent Co-Authors

Robin F. Irvine
Robin F. Irvine University of Cambridge
Wim J. van Blitterswijk
Wim J. van Blitterswijk Antoni van Leeuwenhoek Hospital
Kees Jalink
Kees Jalink Antoni van Leeuwenhoek Hospital
Shabaz Mohammed
Shabaz Mohammed University of Oxford
Jacco van Rheenen
Jacco van Rheenen Antoni van Leeuwenhoek Hospital
Teun Munnik
Teun Munnik University of Amsterdam
Wouter H. Moolenaar
Wouter H. Moolenaar Antoni van Leeuwenhoek Hospital
Peter L. Hordijk
Peter L. Hordijk University of Amsterdam
Hans Janssen
Hans Janssen KU Leuven
Bryan Charleston
Bryan Charleston The Pirbright Institute

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