Nullin Divecha spends much of his time researching Cell biology, Biochemistry, Signal transduction, Kinase and Inositol. His work in Phosphatidylinositol, Phosphatidylinositol 5-phosphate, Diacylglycerol kinase, Wortmannin and Endosome is related to Cell biology. Nullin Divecha combines topics linked to Second messenger system with his work on Phosphatidylinositol.
His work deals with themes such as Cell nucleus and Diglyceride, which intersect with Diacylglycerol kinase. The study incorporates disciplines such as DNA damage and DNA repair in addition to Kinase. In his research, Cell growth is intimately related to Pi, which falls under the overarching field of Phosphorylation.
Cell biology, Kinase, Biochemistry, Phosphatidylinositol and Phosphorylation are his primary areas of study. His studies link Molecular biology with Cell biology. His Kinase research is multidisciplinary, relying on both Apoptosis, Neurite and Gene isoform.
His Phosphatidylinositol research incorporates themes from Cell signaling and Endocrinology. His Phosphorylation study combines topics in areas such as Extracellular, Amino acid and Cell growth. His Signal transduction research integrates issues from Receptor and Function.
His primary areas of study are Cell biology, Kinase, Cell growth, Phosphatidylinositol and PI3K/AKT/mTOR pathway. His biological study focuses on Signal transduction. Nullin Divecha has included themes like Oxidative stress and TFEB in his Kinase study.
His Cell growth research is multidisciplinary, incorporating perspectives in Progenitor cell, Haematopoiesis, Myeloid leukemia and Leukemia. Nullin Divecha is investigating Biochemistry and Phosphorylation as part of his examination of Phosphatidylinositol. His PI3K/AKT/mTOR pathway research includes themes of Endocrinology, Insulin, Protein kinase B, Extracellular and Glycolysis.
His scientific interests lie mostly in Cell biology, Kinase, Cell growth, PI3K/AKT/mTOR pathway and Chromatin. His Cell nucleus study, which is part of a larger body of work in Cell biology, is frequently linked to RNA splicing, bridging the gap between disciplines. While the research belongs to areas of Kinase, Nullin Divecha spends his time largely on the problem of Signal transduction, intersecting his research to questions surrounding Drosophila Protein.
His biological study spans a wide range of topics, including Haematopoiesis, Progenitor cell, Myeloid leukemia, Leukemia and Clonogenic assay. His PI3K/AKT/mTOR pathway research incorporates themes from Oxidative stress and PIKFYVE. His studies deal with areas such as Transcription Factor TFIID, Gene expression and Cellular differentiation as well as Chromatin.
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Mammalian SIRT1 Represses Forkhead Transcription Factors
Maria Carla Motta;Nullin Divecha;Madeleine Lemieux;Christopher Kamel.
DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product
Katharine O Hartley;David Gell;Graeme C.M Smith;Hong Zhang.
The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase C to the nucleus.
N Divecha;H Banfić;R F Irvine.
The EMBO Journal (1991)
The PHD Finger of the Chromatin-Associated Protein ING2 Functions as a Nuclear Phosphoinositide Receptor
Or Gozani;Philip Karuman;David R. Jones;Dmitri Ivanov.
PIP5K-driven PtdIns(4,5)P2 synthesis: regulation and cellular functions
Iman van den Bout;Nullin Divecha.
Journal of Cell Science (2009)
Multivesicular body morphogenesis requires phosphatidyl-inositol 3-kinase activity.
Mar Fernandez-Borja;Richard Wubbolts;Jero Calafat;Hans Janssen.
Current Biology (1999)
Inositides and the nucleus and inositides in the nucleus
Nullin Divecha;Hrvoje Banfić;Robin F. Irvine.
Evaluation and Optimization of ZIC-HILIC-RP as an Alternative MudPIT Strategy
Paul J. Boersema;Nullin Divecha;Albert J. R. Heck;Shabaz Mohammed.
Journal of Proteome Research (2007)
Phosphoinositide signalling enzymes in rat liver nuclei: phosphoinositidase C isoform β1 is specifically, but not predominantly, located in the nucleus
N. Divecha;Sue-Goo Rhee;A. J. Letcher;R. F. Irvine.
Biochemical Journal (1993)
Phospholipid signalling in the nucleus. Een DAG uit het leven van de inositide signalering in de nucleus.
C.S. D’Santos;J.H. Clarke;N. Divecha.
Biochimica et Biophysica Acta (1998)
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