What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Molecular biology, DNA repair, Cell biology, DNA damage and DNA.
His research in Molecular biology intersects with topics in Protein kinase A, Phosphorylation, Histone, Chromatin and Nuclear protein.
His biological study spans a wide range of topics, including Autophosphorylation, Homologous recombination and Kinase activity.
His Cell biology study integrates concerns from other disciplines, such as Genetics, Cellular differentiation, Genome instability and Chromosome breakage.
His Double Strand Break Repair study in the realm of DNA damage connects with subjects such as Premature aging.
His study looks at the relationship between DNA and fields such as DNA-binding protein, as well as how they intersect with chemical problems.
His most cited work include:
- Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer (2028 citations)
- ATM Phosphorylates Histone H2AX in Response to DNA Double-strand Breaks (1482 citations)
- Telomere Shortening Triggers Senescence of Human Cells through a Pathway Involving ATM, p53, and p21CIP1, but Not p16INK4a (976 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Molecular biology, DNA repair, DNA damage, Cell biology and DNA.
His Molecular biology study incorporates themes from Ku80, Protein kinase A, Homologous recombination, Ku70 and Mutant.
As a member of one scientific family, David J. Chen mostly works in the field of DNA repair, focusing on Replication protein A and, on occasion, Nucleotide excision repair.
His research on DNA damage also deals with topics like
- Chromatin that intertwine with fields like Histone,
- Cell cycle which connect with Cancer research.
He works in the field of Cell biology, focusing on Phosphorylation in particular.
His studies in DNA integrate themes in fields like Biophysics and DNA-binding protein.
He most often published in these fields:
- Molecular biology (45.61%)
- DNA repair (32.01%)
- DNA damage (27.20%)
What were the highlights of his more recent work (between 2011-2021)?
- DNA damage (27.20%)
- DNA repair (32.01%)
- Cell biology (25.50%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in DNA damage, DNA repair, Cell biology, Molecular biology and DNA.
As a part of the same scientific study, David J. Chen usually deals with the DNA damage, concentrating on Ataxia Telangiectasia Mutated Proteins and frequently concerns with Kinase.
The study incorporates disciplines such as Cancer research, Ubiquitin, Ku80, Cell killing and DNA replication in addition to DNA repair.
His research investigates the link between Cell biology and topics such as DNA repair protein XRCC4 that cross with problems in XRCC2 and DNA Repair Pathway.
David J. Chen has included themes like Chromatin, Poly ADP ribose polymerase, Mutant and Homologous recombination in his Molecular biology study.
His DNA research includes elements of Biophysics and Live cell imaging.
Between 2011 and 2021, his most popular works were:
- The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response. (394 citations)
- DNA double strand break repair via non-homologous end-joining (318 citations)
- DNA-PK: A dynamic enzyme in a versatile DSB repair pathway (195 citations)
In his most recent research, the most cited papers focused on:
DNA repair, DNA damage, Molecular biology, Cell biology and DNA are his primary areas of study.
His studies deal with areas such as P53 binding, Cancer research, Live cell imaging, Dose fractionation and Chromatin as well as DNA repair.
His DNA damage research incorporates elements of Transport protein, Cell cycle checkpoint, Cell growth and Protein–protein interaction.
Ku70, Ku80, S phase and Cell cycle is closely connected to Homologous recombination in his research, which is encompassed under the umbrella topic of Molecular biology.
His Cell biology study combines topics from a wide range of disciplines, such as DNA End-Joining Repair, Ataxia Telangiectasia Mutated Proteins, Biochemistry and DNA repair protein XRCC4.
His work deals with themes such as Ionizing radiation and High doses, which intersect with DNA.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
