What is she best known for?
The fields of study she is best known for:
Susan P. Lees-Miller focuses on DNA repair, Protein kinase A, Molecular biology, Biochemistry and DNA damage.
Her DNA repair research entails a greater understanding of DNA.
Particularly relevant to DNA-Dependent Protein Kinase Catalytic Subunit is her body of work in Protein kinase A.
In the field of Biochemistry, her study on Protein phosphorylation and HMG-box overlaps with subjects such as DNA binding site and Binding domain.
Her biological study spans a wide range of topics, including Kinase and Cell biology.
Susan P. Lees-Miller works mostly in the field of DNA repair protein XRCC4, limiting it down to topics relating to DNA ligase and, in certain cases, Ku70 and Ku80.
Her most cited work include:
- DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product (663 citations)
- GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase (560 citations)
- Repair of ionizing radiation-induced DNA double strand breaks by non-homologous end-joining (544 citations)
What are the main themes of her work throughout her whole career to date?
Her primary areas of study are Molecular biology, DNA repair, Protein kinase A, Cell biology and Biochemistry.
Her research in Molecular biology intersects with topics in Cell cycle, Nuclear protein and Phosphatase.
Her work is dedicated to discovering how DNA repair, Ku80 are connected with Ku70 and other disciplines.
The study incorporates disciplines such as Protein subunit and Kinase activity in addition to Protein kinase A.
Susan P. Lees-Miller has researched Cell biology in several fields, including DNA damage, DNA, G2-M DNA damage checkpoint and DNA-binding protein.
Her studies deal with areas such as Replication protein A and DNA ligase as well as DNA repair protein XRCC4.
She most often published in these fields:
- Molecular biology (31.94%)
- DNA repair (31.94%)
- Protein kinase A (29.84%)
What were the highlights of her more recent work (between 2013-2021)?
- DNA repair (31.94%)
- Cell biology (28.80%)
- Cervical cancer (11.52%)
In recent papers she was focusing on the following fields of study:
Susan P. Lees-Miller mostly deals with DNA repair, Cell biology, Cervical cancer, Internal medicine and Oncology.
The concepts of her DNA repair study are interwoven with issues in Molecular biology and Ku80.
She interconnects DNA ligase, DNA and Ku70 in the investigation of issues within Cell biology.
To a larger extent, she studies Biochemistry with the aim of understanding DNA ligase.
Her research investigates the connection between DNA and topics such as Protein subunit that intersect with issues in Autophosphorylation.
MAP2K7 is the focus of her Protein kinase A research.
Between 2013 and 2021, her most popular works were:
- Non-homologous end joining: emerging themes and unanswered questions. (90 citations)
- Structural insights into NHEJ: Building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time (80 citations)
- ATM-Deficient Colorectal Cancer Cells Are Sensitive to the PARP Inhibitor Olaparib (56 citations)
In her most recent research, the most cited papers focused on:
Susan P. Lees-Miller mainly focuses on Cancer research, DNA repair protein XRCC4, Cell biology, Olaparib and PARP inhibitor.
DNA repair covers Susan P. Lees-Miller research in DNA repair protein XRCC4.
Her DNA repair study deals with Ku80 intersecting with Ku70, Molecular biology and DNA-PKcs.
Her Cell biology research incorporates elements of Sgs1, DNA and Yeast.
Her study in Olaparib is interdisciplinary in nature, drawing from both Ataxia-telangiectasia, DNA damage, Lung cancer and Protein kinase A.
Her study on DNA ligase is covered under Biochemistry.
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