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D-Index & Metrics

Molecular Biology

D-Index
104
Citations
42737
World Ranking
463
National Ranking
261

Overview

Michael R. Lieber is affiliated with the University of Southern California in the United States. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with a strong focus on DNA repair mechanisms.

The scientist has published extensively in primary fields such as:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their subfields of study include:

  • Molecular Biology
  • Oncology
  • Genetics
  • Public Health, Environmental and Occupational Health
  • Immunology

Key research topics covered in their work are:

  • DNA Repair Mechanisms
  • DNA and Nucleic Acid Chemistry
  • CRISPR and Genetic Engineering
  • Acute Lymphoblastic Leukemia research
  • Cancer therapeutics and mechanisms
  • Genetics and Neurodevelopmental Disorders
  • T-cell and B-cell Immunology

Michael R. Lieber has collaborated frequently with several researchers, including:

  • Chih-Lin Hsieh (10 joint publications)
  • Go Watanabe (7 joint publications)
  • Cindy Yen Okitsu (5 joint publications)
  • Eli Rothenberg (4 joint publications)
  • Dale A. Ramsden (4 joint publications)

The scientist's recent papers showcase their focus on molecular mechanisms involved in DNA repair and structural biology. Notable publications include:

  • "The molecular basis and disease relevance of non-homologous DNA end joining," 2020, Nature Reviews Molecular Cell Biology
  • "Structural analysis of the basal state of the Artemis:DNA-PKcs complex," 2022, Nucleic Acids Research
  • "Structural analysis of the catalytic domain of Artemis endonuclease/SNM1C reveals distinct structural features," 2020, Journal of Biological Chemistry
  • "Polymerase μ in non-homologous DNA end joining: importance of the order of arrival at a double-strand break in a purified system," 2020, Nucleic Acids Research
  • "Dynamics of the Artemis and DNA-PKcs Complex in the Repair of Double-Strand Breaks," 2022, Journal of Molecular Biology

The venues in which Michael R. Lieber publishes most frequently include:

  • Nucleic Acids Research
  • UNC Libraries
  • DNA Repair
  • Molecular Immunology
  • Leukemia

Best Publications

  • The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

    Michael R. Lieber

  • A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells.

    Michael Lieber;George Todaro;Barry Smith;Andras Szakal

  • Hairpin Opening and Overhang Processing by an Artemis/DNA-Dependent Protein Kinase Complex in Nonhomologous End Joining and V(D)J Recombination

    Yunmei Ma;Ulrich Pannicke;Klaus Schwarz;Michael R. Lieber

  • Non-homologous DNA end joining and alternative pathways to double-strand break repair.

    Howard H. Y. Chang;Nicholas R. Pannunzio;Noritaka Adachi;Michael R. Lieber

  • Mechanism and regulation of human non-homologous DNA end-joining

    Michael R. Lieber;Yunmei Ma;Ulrich Pannicke;Klaus Schwarz

  • Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

    Ulf Grawunder;Matthias Wilm;Matthias Wilm;Xiantuo Wu;Xiantuo Wu;Peter Kulesza;Peter Kulesza

  • The mechanism of human nonhomologous DNA end joining.

    Michael R. Lieber

  • R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

    Kefei Yu;Frederic Chedin;Chih Lin Hsieh;Thomas E. Wilson

  • RAG Mutations in Human B Cell-Negative SCID

    Klaus Schwarz;George H. Gauss;Leopold Ludwig;Ulrich Pannicke

  • Establishment of a continuous tumor‐cell line (PANC‐1) from a human carcinoma of the exocrine pancreas

    Michael Lieber;Joann Mazzetta;Walter Nelson-Rees;Michael Kaplan

  • The FEN-1 family of structure-specific nucleases in eukaryotic dna replication, recombination and repair

    Michael R. Lieber

  • V(D)J recombination: a functional definition of the joining signals.

    Joanne E. Hesse;Michael R. Lieber;Kiyoshi Mizuuchi;Martin Gellert

  • The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a

    Frédéric Chédin;Michael R. Lieber;Chih-Lin Hsieh

  • The characterization of a mammalian DNA structure-specific endonuclease.

    J.J. Harrington;M.R. Lieber

  • Yeast DNA ligase IV mediates non-homologous DNA end joining

    Thomas E. Wilson;Ulf Grawunder;Michael R. Lieber

  • The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination

    Michael R. Lieber;Joanne E. Hesse;Susanna Lewis;Gayle C. Bosma

  • Nonhomologous DNA end-joining for repair of DNA double-strand breaks

    Nicholas R. Pannunzio;Go Watanabe;Michael R. Lieber

  • Bidirectional gene organization: a common architectural feature of the human genome.

    Noritaka Adachi;Noritaka Adachi;Michael R. Lieber

  • Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection

    Ling Li;Jennifer M. Olvera;Kristine E. Yoder;Richard S. Mitchell

  • Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals.

    Joanne E. Hesse;Joanne E. Hesse;Michael R. Lieber;Michael R. Lieber;Martin Gellert;Martin Gellert;Kiyoshi Mizuuchi;Kiyoshi Mizuuchi

Frequent Co-Authors

Chih-Lin Hsieh
Chih-Lin Hsieh University of Southern California
klaus schwarz
klaus schwarz University of Ulm
Sathees C. Raghavan
Sathees C. Raghavan Indian Institute of Science
Markus Müschen
Markus Müschen Yale University
Martin Gellert
Martin Gellert National Institute of Diabetes and Digestive and Kidney Diseases
Kiyoshi Mizuuchi
Kiyoshi Mizuuchi National Institutes of Health
Rafael Casellas
Rafael Casellas The University of Texas MD Anderson Cancer Center
David G. Schatz
David G. Schatz Yale University
David Van Den Berg
David Van Den Berg University of Southern California
Mel Greaves
Mel Greaves Institute of Cancer Research

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