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D-Index & Metrics

Molecular Biology

D-Index
52
Citations
12549
World Ranking
2421
National Ranking
1194

Overview

Craig H. Bassing is affiliated with the Children's Hospital of Philadelphia in the United States. Their research primarily focuses on immunology and microbiology, with substantial work in biochemistry, genetics, and molecular biology. The core subfields include immunology, molecular biology, oncology, genetics, and plant science.

The scientist's main topics of investigation encompass T-cell and B-cell immunology, immune cell function and interaction, DNA repair mechanisms, genomics and chromatin dynamics, CAR-T cell therapy research, immunotherapy and immune responses, as well as RNA and protein synthesis mechanisms.

Frequent publication venues for Craig H. Bassing include The Journal of Immunology, bioRxiv (Cold Spring Harbor Laboratory), The Journal of Experimental Medicine, Nature Communications, and Proceedings of the National Academy of Sciences.

They have collaborated often with several co-authors, notably Katharina E. Hayer, Eugene M. Oltz, Brittney M. Allyn, Vincent Nganga, and Rebecca A. Glynn.

Their recent papers include:

  • DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner, 2020, Nature Communications
  • The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination, 2021, The Journal of Experimental Medicine
  • Poor quality Vβ recombination signal sequences stochastically enforce TCRβ allelic exclusion, 2020, The Journal of Experimental Medicine
  • Inefficient V(D)J recombination underlies monogenic T cell receptor β expression, 2020, Proceedings of the National Academy of Sciences
  • Locus folding mechanisms determine modes of antigen receptor gene assembly, 2024, The Journal of Experimental Medicine

Best Publications

  • The Mechanism and Regulation of Chromosomal V(D)J Recombination

    Craig H Bassing;Wojciech Swat;Frederick W Alt

  • BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

    Ann Marie Pendergast;Lawrence A. Quilliam;Larry D. Cripe;Craig H. Bassing

  • Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

    Craig H. Bassing;Katrin F. Chua;Jo Ann Sekiguchi;Heikyung Suh

  • Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors.

    Craig H. Bassing;Heikyung Suh;David O. Ferguson;David O. Ferguson;Katrin F. Chua

  • ATM stabilizes DNA double-strand-break complexes during V(D)J recombination.

    Andrea L. Bredemeyer;Girdhar G. Sharma;Ching Yu Huang;Beth A. Helmink

  • A transforming growth factor beta type I receptor that signals to activate gene expression

    Craig H. Bassing;Jonathan M. Yingling;David J. Howe;Tongwen Wang

  • The cellular response to general and programmed DNA double strand breaks

    Craig H. Bassing;Frederick W. Alt;Frederick W. Alt

  • Mechanism and Control of V(D)J Recombination versus Class Switch Recombination: Similarities and Differences

    Darryll D Dudley;Jayanta Chaudhuri;Craig H Bassing;Frederick W Alt

  • H2AX Prevents DNA Breaks from Progressing to Chromosome Breaks and Translocations

    Sonia Franco;Monica Gostissa;Shan Zha;David B. Lombard

  • Control of Sister Chromatid Recombination by Histone H2AX

    Anyong Xie;Nadine Puget;Inbo Shim;Shobu Odate

  • Activating Notch1 mutations in mouse models of T-ALL.

    Jennifer Elinor O'Neil;Jennifer Ann Calvo;Keith McKenna;Veena Krishnamoorthy

  • Elucidation of IgH intronic enhancer functions via germ-line deletion

    Thomas Perlot;Frederick W. Alt;Craig H. Bassing;Heikyung Suh

  • Formation of Dynamic γ-H2AX Domains along Broken DNA Strands is Distinctly Regulated by ATM and MDC1 and Dependent upon H2AX Densities in Chromatin

    Velibor Savic;Bu Yin;Nancy L. Maas;Andrea L. Bredemeyer

  • Expression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression.

    James K. Schwarz;Craig H. Bassing;Imre Kovesdi;Michael B. Datto

  • Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.

    Bassing Ch;Alt Fw;Hughes Mm;D'Auteuil M

  • A 3′ Enhancer in the IL-4 Gene Regulates Cytokine Production by Th2 Cells and Mast Cells

    Deborah C. Solymar;Suneet Agarwal;Craig H. Bassing;Craig H. Bassing;Frederick W. Alt;Frederick W. Alt

  • Functional Interaction of H2AX, NBS1, and p53 in ATM-Dependent DNA Damage Responses and Tumor Suppression

    Jian Kang;David Ferguson;Hoseok Song;Craig Bassing

  • DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes

    Andrea L. Bredemeyer;Beth A. Helmink;Cynthia L. Innes;Boris Calderon

  • ATR and H2AX Cooperate in Maintaining Genome Stability under Replication Stress

    Rebecca A. Chanoux;Bu Yin;Bu Yin;Karen A. Urtishak;Amma Asare

  • Antigen Receptor Allelic Exclusion: An Update and Reappraisal

    Brenna L. Brady;Natalie C. Steinel;Craig H. Bassing

Frequent Co-Authors

Frederick W. Alt
Frederick W. Alt Boston Children's Hospital
Barry P. Sleckman
Barry P. Sleckman University of Alabama at Birmingham
David G. Schatz
David G. Schatz Yale University
Xiao-Fan Wang
Xiao-Fan Wang Duke University
Jane A. Skok
Jane A. Skok New York University
Konrad Hochedlinger
Konrad Hochedlinger Harvard University
Michael S. Krangel
Michael S. Krangel Duke University
Tej K. Pandita
Tej K. Pandita Houston Methodist
Anjana Rao
Anjana Rao La Jolla Institute For Allergy & Immunology

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