Michel Cogné mainly investigates Molecular biology, Enhancer, Genetics, Immunoglobulin class switching and Antibody. The Molecular biology study combines topics in areas such as Plasma cell, Genetically modified mouse, Transgene, Immunoglobulin light chain and Exon. To a larger extent, Michel Cogné studies Gene with the aim of understanding Enhancer.
Michel Cogné combines subjects such as Isotype, Immunoglobulin heavy chain and Immunoglobulin D with his study of Immunoglobulin class switching. His research in Immunoglobulin heavy chain intersects with topics in Affinity maturation, Somatic hypermutation, B cell and Locus. In his work, Immunoglobulin E and Mutation is strongly intertwined with Gene rearrangement, which is a subfield of Antibody.
His primary scientific interests are in Molecular biology, Antibody, Immunology, Immunoglobulin class switching and Genetics. His Molecular biology research includes elements of Gene, Transgene, Immunoglobulin heavy chain, B cell and Immunoglobulin light chain. Michel Cogné regularly ties together related areas like Gene rearrangement in his Antibody studies.
In his study, Cytidine deaminase is inextricably linked to Somatic hypermutation, which falls within the broad field of Immunoglobulin class switching. His study in Enhancer, Transcription, Allele, Recombination and Igh locus falls under the purview of Genetics. His Enhancer research includes themes of Promoter and Tandem repeat.
His scientific interests lie mostly in Immunoglobulin class switching, B cell, Genetics, Antibody and Molecular biology. His Immunoglobulin class switching study combines topics in areas such as Somatic hypermutation, Gene, Allele, Germline and Cell biology. His B cell research is multidisciplinary, incorporating elements of breakpoint cluster region and In vitro.
His Genetics and Enhancer, Igh locus and Noncoding DNA investigations all form part of his Genetics research activities. His research links Transgene with Antibody. His Molecular biology research incorporates themes from Immunoglobulin light chain, Proteasome inhibitor, Germline mutation and Immunoglobulin heavy chain.
Michel Cogné mainly focuses on Immunoglobulin class switching, Enhancer, Genetics, Immunoglobulin heavy chain and B cell. His work in Immunoglobulin class switching addresses subjects such as Germline, which are connected to disciplines such as Regulatory region, Mutation, Cytidine deaminase and Germline mutation. His work in Immunoglobulin heavy chain addresses issues such as Somatic hypermutation, which are connected to fields such as Immunoglobulin D and Transcription factor.
His study with B cell involves better knowledge in Antibody. His Antibody study is concerned with Immunology in general. Michel Cogné has researched breakpoint cluster region in several fields, including Molecular biology and Marginal zone B-cell.
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High-dose melphalan versus melphalan plus dexamethasone for AL amyloidosis.
Arnaud Jaccard;Philippe Moreau;Véronique Leblond;Xavier Leleu.
The New England Journal of Medicine (2007)
A class switch control region at the 3′ end of the immunoglobulin heavy chain locus
Michel Cogné;Michel Cogné;Rusty Lansford;Andrea Bottaro;Andrea Bottaro;Jue Zhang.
S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase.
Robert Wuerffel;Lili Wang;Fernando Grigera;John Manis.
Localization of the 3′ IgH Locus Elements that Effect Long-Distance Regulation of Class Switch Recombination
Eric Pinaud;Ahmed Amine Khamlichi;Caroline Le Morvan;Mireille Drouet.
The Igκ 3′ Enhancer Influences the Ratio of Igκ versus Igλ B Lymphocytes
James R Gorman;Nienke van der Stoep;Robert Monroe;Michel Cogne.
IGHV gene features and MYD88 L265P mutation separate the three marginal zone lymphoma entities and Waldenström macroglobulinemia/lymphoplasmacytic lymphomas
Nathalie Gachard;M. Parrens;Isabelle Soubeyran;Barbara Petit.
Monoclonal immunoglobulin deposition disease (Randall type). Relationship with structural abnormalities of immunoglobulin chains
Jean-Louis Preud'homme;Pierre Aucouturier;Guy Touchard;Liliane Striker.
Kidney International (1994)
The 3' IgH regulatory region: a complex structure in a search for a function.
Ahmed Amine Khamlichi;Eric Pinaud;Catherine Decourt;Christine Chauveau.
Advances in Immunology (2000)
Genomic deletion of the whole IgH 3′ regulatory region (hs3a, hs1,2, hs3b, and hs4) dramatically affects class switch recombination and Ig secretion to all isotypes
Christelle Vincent-Fabert;Remi Fiancette;Eric Pinaud;Véronique Truffinet.
Loss of the HVEM tumor suppressor in lymphoma and restoration by modified CAR-T cells
Michael Boice;Michael Boice;Darin Salloum;Frederic Mourcin;Viraj Sanghvi.
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