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Immunology
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2026

D-Index & Metrics

Best Scientists

D-Index
199
Citations
130054
World Ranking
307
National Ranking
205

Immunology

D-Index
198
Citations
132512
World Ranking
12
National Ranking
7

Molecular Biology

D-Index
200
Citations
133122
World Ranking
21
National Ranking
14

Frederick W. Alt publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Frederick W. Alt sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 68 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 621 publications — 95th percentile

95% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

Frederick W. Alt D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Frederick W. Alt sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 162 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 198 D-Index — 100th percentile

100% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in United States Leader Award
  • 2020 - Distinguished Fellows of the American Association of Immunologists (AAI)
  • 2019 - AAI-BioLegend Herzenberg Award, American Association of Immunologists
  • 2015 - Szent-Györgyi Prize for Progress in Cancer Research, National Foundation for Cancer Research (NFCR)
  • 2011 - Member of the National Academy of Medicine (NAM)
  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2004 - Robert J. and Claire Pasarow Foundation Medical Research Award
  • 2003 - AAI Excellence in Mentoring Award, American Association of Immunologists
  • 1994 - Member of the National Academy of Sciences
  • 1994 - Fellow of the American Academy of Arts and Sciences

Overview

Frederick W. Alt is affiliated with Boston Children's Hospital in the United States. Their research primarily spans the fields of Immunology and Microbiology, Biochemistry, Genetics and Molecular Biology, and Medicine, with a strong focus on subfields such as Immunology, Molecular Biology, Virology, Radiology, Nuclear Medicine and Imaging, and Infectious Diseases.

The main topics covered in Frederick W. Alt's research include T-cell and B-cell Immunology, Immune Cell Function and Interaction, HIV Research and Treatment, Monoclonal and Polyclonal Antibodies Research, Genomics and Chromatin Dynamics, Immunotherapy and Immune Responses, and DNA Repair Mechanisms.

Frederick W. Alt has contributed to numerous publications in notable scientific venues. These frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Nature, Proceedings of the National Academy of Sciences, Nature Reviews Immunology, and Nature Communications.

Recent papers authored or co-authored by Frederick W. Alt include:

  • Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies, 2022, Nature Reviews Immunology
  • eccDNAs are apoptotic products with high innate immunostimulatory activity, 2021, Nature
  • BCR selection and affinity maturation in Peyer's patch germinal centres, 2020, Nature
  • CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning, 2020, Nature
  • The role of chromatin loop extrusion in antibody diversification, 2022, Nature Reviews Immunology

Frederick W. Alt has collaborated frequently with several researchers, including:

  • Ming Tian
  • Adam Yongxin Ye
  • Barton F. Haynes
  • Kevin O. Saunders
  • Aimee Williams

Their career includes several awards and recognitions such as:

  • Distinguished Fellows of the American Association of Immunologists (AAI), 2020
  • AAI-BioLegend Herzenberg Award, American Association of Immunologists, 2019
  • Szent-Györgyi Prize for Progress in Cancer Research, National Foundation for Cancer Research (NFCR), 2015
  • Member of the National Academy of Medicine (NAM), 2011
  • Fellow of the American Association for the Advancement of Science (AAAS), 2010
  • Robert J. and Claire Pasarow Foundation Medical Research Award, 2004
  • AAI Excellence in Mentoring Award, American Association of Immunologists, 2003
  • Member of the National Academy of Sciences, 1994
  • Fellow of the American Academy of Arts and Sciences, 1994

Best Publications

  • Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase

    Anne Brunet;Lora B. Sweeney;J. Fitzhugh Sturgill;Katrin F. Chua

  • RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

    Yoichi Shinkai;Gary Rathbun;Kong-Peng Lam;Eugene M. Oltz

  • Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

    Raul Mostoslavsky;Katrin F. Chua;Katrin F. Chua;David B. Lombard;Wendy W. Pang

  • SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

    Matthew D. Hirschey;Tadahiro Shimazu;Tadahiro Shimazu;Eric Goetzman;Enxuan Jing

  • An early haematopoietic defect in mice lacking the transcription factor GATA-2.

    Fong-Ying Tsai;Fong-Ying Tsai;Gordon Keller;Frank C. Kuo;Mitchell Weiss

  • A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

    In Hye Lee;Liu Cao;Raul Mostoslavsky;David B. Lombard

  • Plasma cell differentiation requires the transcription factor XBP-1

    Andreas M. Reimold;Neal N. Iwakoshi;John Manis;Prashanth Vallabhajosyula

  • Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α

    Zachary Gerhart-Hines;Zachary Gerhart-Hines;Joseph T. Rodgers;Joseph T. Rodgers;Olivia Bare;Carles Lerin;Carles Lerin

  • SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

    Gad Asher;David Gatfield;Markus Stratmann;Hans Reinke

  • Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.

    David B. Lombard;Frederick W. Alt;Hwei Ling Cheng;Jakob Bunkenborg

  • SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells

    Marcia C. Haigis;Raul Mostoslavsky;Kevin M. Haigis;Kamau Fahie

  • Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

    Dennis M. Willerford;Jianzhu Chen;Judith A. Ferry;Laurie Davidson

  • Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

    Hwei-Ling Cheng;Raul Mostoslavsky;Shin'ichi Saito;John P. Manis

  • Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

    Merja Lakso;Jose G. Pichel;James R. Gorman;Brian Sauer

  • The Mechanism and Regulation of Chromosomal V(D)J Recombination

    Craig H Bassing;Wojciech Swat;Frederick W Alt

  • DNA Repair, Genome Stability, and Aging

    David B. Lombard;Katrin F. Chua;Raul Mostoslavsky;Sonia Franco

  • Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation

    Tracy Blunt;Nicholas J Finnie;Guillermo E Taccioli;Guillermo E Taccioli;Graeme C.M Smith

  • Ordered rearrangement of immunoglobulin heavy chain variable region segments.

    F W Alt;G D Yancopoulos;T K Blackwell;C Wood

  • Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions.

    Frederick W. Alt;David Baltimore

  • SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging

    Philipp Oberdoerffer;Shaday Michan;Michael McVay;Raul Mostoslavsky

Frequent Co-Authors

John P. Manis
John P. Manis Boston Children's Hospital
Laurie Davidson
Laurie Davidson Howard Hughes Medical Institute
Craig H. Bassing
Craig H. Bassing Children's Hospital of Philadelphia
George D. Yancopoulos
George D. Yancopoulos Regeneron (United States)
Raul Mostoslavsky
Raul Mostoslavsky Harvard University
Scott B. Snapper
Scott B. Snapper Boston Children's Hospital
Ronald A. DePinho
Ronald A. DePinho The University of Texas MD Anderson Cancer Center
Wojciech Swat
Wojciech Swat Washington University in St. Louis
Jo Ann Sekiguchi
Jo Ann Sekiguchi University of Michigan–Ann Arbor
David B. Lombard
David B. Lombard University of Michigan–Ann Arbor

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