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Molecular Biology

D-Index
54
Citations
16590
World Ranking
2303
National Ranking
1134

John P. Manis publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where John P. Manis sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 109 publications — 16th percentile

16% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

John P. Manis D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where John P. Manis sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 54 D-Index — 26th percentile

26% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Overview

John P. Manis is affiliated with Boston Children's Hospital in the United States and has a primary research focus within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields, notably Molecular Biology, Genetics, Immunology, Hematology, and Pediatrics, Perinatology and Child Health.

The main topics covered in Manis's research include:

  • Hemoglobinopathies and Related Disorders
  • CRISPR and Genetic Engineering
  • Prenatal Screening and Diagnostics
  • Virus-based gene therapy research
  • Erythrocyte Function and Pathophysiology
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology

Manis has contributed frequently to several scientific journals. The most common publication venues are:

  • Blood
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood Advances
  • Transfusion
  • New England Journal of Medicine

Frequent collaborators include:

  • Christian Brendel
  • David A. Williams
  • Daniel E. Bauer
  • David G. Justus
  • Myriam Armant

Some recent papers authored or co-authored by John P. Manis are:

  • "Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease," 2020, published in New England Journal of Medicine
  • "Therapeutic base editing of human hematopoietic stem cells," 2020, published in Nature Medicine
  • "Preclinical Evaluation of a Novel Lentiviral Vector Driving Lineage-Specific BCL11A Knockdown for Sickle Cell Gene Therapy," 2020, published in Molecular Therapy - Methods & Clinical Development
  • "Targeting multiple cell death pathways extends the shelf life and preserves the function of human and mouse neutrophils for transfusion," 2021, published in Science Translational Medicine
  • "Antibody-mediated antigen loss switches augmented immunity to antibody-mediated immunosuppression," 2023, published in Blood

Best Publications

  • Plasma cell differentiation requires the transcription factor XBP-1

    Andreas M. Reimold;Neal N. Iwakoshi;John Manis;Prashanth Vallabhajosyula

  • Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

    Hwei-Ling Cheng;Raul Mostoslavsky;Shin'ichi Saito;John P. Manis

  • MDC1 Maintains Genomic Stability by Participating in the Amplification of ATM-Dependent DNA Damage Signals

    Zhenkun Lou;Katherine Minter-Dykhouse;Sonia Franco;Monica Gostissa

  • Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

    Yijie Gao;David O. Ferguson;David O. Ferguson;Wei Xie;John P. Manis

  • IgH class switching and translocations use a robust non-classical end-joining pathway

    Catherine T. Yan;Cristian Boboila;Ellen Kris Souza;Sonia Franco

  • Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors.

    Craig H. Bassing;Heikyung Suh;David O. Ferguson;David O. Ferguson;Katrin F. Chua

  • Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

    Chengming Zhu;Kevin D. Mills;David O. Ferguson;Charles Lee

  • Mechanism and control of class-switch recombination

    John P Manis;Ming Tian;Frederick W Alt

  • DNA Ligase IV Deficiency in Mice Leads to Defective Neurogenesis and Embryonic Lethality via the p53 Pathway

    Karen M. Frank;Norman E. Sharpless;Yijie Gao;Jo Ann M. Sekiguchi

  • Growth Retardation and Leaky SCID Phenotype of Ku70-Deficient Mice

    Yansong Gu;Katherine J. Seidl;Gary A. Rathbun;Chengming Zhu

  • Highly efficient therapeutic gene editing of human hematopoietic stem cells.

    Yuxuan Wu;Jing Zeng;Jing Zeng;Benjamin P. Roscoe;Pengpeng Liu

  • Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease

    Erica B. Esrick;Leslie E. Lehmann;Alessandra Biffi;Maureen Achebe

  • 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination

    John P Manis;Julio C Morales;Zhenfang Xia;Jeffery L Kutok

  • Ku70 Is Required for Late B Cell Development and Immunoglobulin Heavy Chain Class Switching

    John P. Manis;Yansong Gu;Rusty Lansford;Eiichiro Sonoda

  • Leaky Scid Phenotype Associated with Defective V(D)J Coding End Processing in Artemis-Deficient Mice

    Sean Rooney;Jo Ann Sekiguchi;Chengming Zhu;Hwei Ling Cheng

  • The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation

    Uttiya Basu;Jayanta Chaudhuri;Jayanta Chaudhuri;Craig Alpert;Shilpee Dutt

  • Evolution of the immunoglobulin heavy chain class switch recombination mechanism.

    Jayanta Chaudhuri;Uttiya Basu;Uttiya Basu;Ali Zarrin;Ali Zarrin;Catherine Yan;Catherine Yan

  • H2AX Prevents DNA Breaks from Progressing to Chromosome Breaks and Translocations

    Sonia Franco;Monica Gostissa;Shan Zha;David B. Lombard

  • S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase.

    Robert Wuerffel;Lili Wang;Fernando Grigera;John Manis

  • Deficiencies of GM-CSF and Interferon γ Link Inflammation and Cancer

    Thomas Enzler;Silke Gillessen;John P. Manis;David Ferguson

Frequent Co-Authors

Frederick W. Alt
Frederick W. Alt Boston Children's Hospital
Raif S. Geha
Raif S. Geha Boston Children's Hospital
Luigi D. Notarangelo
Luigi D. Notarangelo National Institutes of Health
David A. Williams
David A. Williams Boston Children's Hospital
Silvia Giliani
Silvia Giliani University of Brescia
Waleed Al-Herz
Waleed Al-Herz Kuwait University
Andrew R. Gennery
Andrew R. Gennery Newcastle University
Laurie Davidson
Laurie Davidson Howard Hughes Medical Institute
Jo Ann Sekiguchi
Jo Ann Sekiguchi University of Michigan–Ann Arbor
Klaus Rajewsky
Klaus Rajewsky Max Delbrück Center for Molecular Medicine

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