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Biology and Biochemistry

D-Index
54
Citations
13838
World Ranking
15449
National Ranking
6448

Overview

Wojciech Swat is affiliated with Washington University in St. Louis in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with significant contributions to medicine. The scientist's work covers diverse subfields including cancer research, genetics, pulmonary and respiratory medicine, and oncology.

The main topics explored in their research include cancer genomics and diagnostics, lung cancer treatments and mutations, cancer immunotherapy and biomarkers, genomics and rare diseases, as well as BRCA gene mutations in cancer.

Their recent publications include:

  • Distributional range of tumor mutational burden (TMB) across multiple cancer types emphasizing the importance of different cutoff values in different tumor types for clinical interpretation: A consensus statement from the SEQUOIA consortium, 2023, Journal of Clinical Oncology
  • A Concordance Study among 26 NGS Laboratories Participating in the NCI Molecular Analysis for Therapy Choice Clinical Trial, 2025, Clinical Cancer Research

Frequent co-authors collaborating with Wojciech Swat are:

  • James P. Solomon
  • Ravindra Kolhe
  • Dibyendu Kumar
  • Theresa A. Boyle
  • Emily Dalton

The scientist has contributed to publications notably within the journals:

  • Journal of Clinical Oncology
  • Clinical Cancer Research

Best Publications

  • The Mechanism and Regulation of Chromosomal V(D)J Recombination

    Craig H Bassing;Wojciech Swat;Frederick W Alt

  • The T Cell Leukemia Oncoprotein SCL/tal-1 Is Essential for Development of All Hematopoietic Lineages

    Catherine Porcher;Wojciech Swat;Wojciech Swat;Karen Rockwell;Yuko Fujiwara;Yuko Fujiwara

  • A Critical Role for DNA End-Joining Proteins in Both Lymphogenesis and Neurogenesis

    Yijie Gao;Yi Sun;Karen M. Frank;Pieter Dikkes

  • Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV.

    Karen M. Frank;Joann M. Sekiguchi;Katherine J. Seidl;Wojciech Swat

  • MHC class I expression in mice lacking the proteasome subunit LMP-7

    HJ Fehling;W Swat;C Laplace;R Kuhn

  • Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

    L.J. Holsinger;I.A. Graef;W. Swat;T. Chi

  • Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

    Rong Zhang;Rong Zhang;Rong Zhang;Frederick W. Alt;Frederick W. Alt;Frederick W. Alt;Laurie Davidson;Stuart H. Orkin

  • Requirement for cyclin D3 in lymphocyte development and T cell leukemias.

    Ewa Sicinska;Iannis Aifantis;Laurent Le Cam;Wojciech Swat

  • The autophagy gene ATG5 plays an essential role in B lymphocyte development.

    Brian C Miller;Zijiang Zhao;Linda M Stephenson;Ken Cadwell

  • The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow

    Li Chun Wang;Wojciech Swat;Yuko Fujiwara;Laurie Davidson

  • Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2

    Sophie E. Acton;Jillian L. Astarita;Deepali Malhotra;Veronika Lukacs-Kornek

  • Vav3 regulates osteoclast function and bone mass

    Roberta Faccio;Roberta Faccio;Steven L Teitelbaum;Keiko Fujikawa;Keiko Fujikawa;Jean Chappel

  • CD69 expression during selection and maturation of CD4+8+ thymocytes.

    Wojciech Swat;Mark Dessing;Harald Von Boehmer;Pawel Kisielow

  • Clonal deletion of immature CD4+8+ thymocytes in suspension culture by extrathymic antigen-presenting cells

    Wojciech Swat;Leszek Ignatowicz;Harald von Boehmer;Pawel Kisielow

  • Detection of apoptosis of immature CD4+8+ thymocytes by flow cytometry

    Wojciech Swat;Leszek Ignatowicz;Pawel Kisielow

  • Vav1/2/3-null Mice Define an Essential Role for Vav Family Proteins in Lymphocyte Development and Activation but a Differential Requirement in MAPK Signaling in T and B Cells

    Keiko Fujikawa;Ana V. Miletic;Frederick W. Alt;Frederick W. Alt;Roberta Faccio

  • Vav GEFs are required for β2 integrin-dependent functions of neutrophils

    M. Angelica Martinez Gakidis;Xavier Cullere;Timothy Olson;Julie L. Wilsbacher

  • Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo

    Hans Reimer Rodewald;Katja Kretzschmar;Wojciech Swat;Shunichi Takeda

  • Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.

    Linda M. Stephenson;Brian C. Miller;Aylwin Ng;Jason Eisenberg

  • Requirements for Vav Guanine Nucleotide Exchange Factors and Rho GTPases in FcγR- and Complement-Mediated Phagocytosis

    Amy B. Hall;M. Angelica Martinez Gakidis;Michael Glogauer;Julie L. Wilsbacher

Frequent Co-Authors

Frederick W. Alt
Frederick W. Alt Boston Children's Hospital
Laurie Davidson
Laurie Davidson Howard Hughes Medical Institute
Roberta Faccio
Roberta Faccio Washington University in St. Louis
Mark L. Kahn
Mark L. Kahn University of Pennsylvania
Kai W. Wucherpfennig
Kai W. Wucherpfennig Harvard University
Ramnik J. Xavier
Ramnik J. Xavier Broad Institute
Michael C. Carroll
Michael C. Carroll Boston Children's Hospital
Stuart H. Orkin
Stuart H. Orkin Harvard University
Yuko Fujiwara
Yuko Fujiwara Harvard University
Jeffrey H. Miner
Jeffrey H. Miner Washington University in St. Louis

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