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Molecular Biology

D-Index
92
Citations
36064
World Ranking
696
National Ranking
380

Overview

Yuko Fujiwara is affiliated with Harvard University in the United States and has an active research portfolio focused mainly on biochemistry, genetics, and molecular biology, with additional work in the field of medicine.

Their research spans several specialized subfields, including molecular biology, surgery, cancer research, genetics, and oncology. The main topics of their work cover:

  • RNA modifications and cancer
  • CRISPR and genetic engineering
  • Epigenetics and DNA methylation
  • Cancer-related molecular mechanisms research
  • Single-cell and spatial transcriptomics
  • RNA research and splicing
  • Hemoglobinopathies and related disorders

Yuko Fujiwara has contributed to multiple research papers published across frequently featured venues. Notable publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • MOKUZAI HOZON (Wood Protection)
  • Cell
  • Cancer Research
  • Blood

Key recent papers authored by Yuko Fujiwara include:

  • "An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells" (2020, Cell)
  • "Enhancer dependence of cell-type-specific gene expression increases with developmental age" (2020, Proceedings of the National Academy of Sciences)
  • "Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells" (2022, Cell Chemical Biology)
  • "E74-Like Factor 3 Is a Key Regulator of Epithelial Integrity and Immune Response Genes in Biliary Tract Cancer" (2020, Cancer Research)

In their scholarly collaborations, Yuko Fujiwara frequently coauthors with the following researchers:

  • Stuart H. Orkin
  • Davide Seruggia
  • Bin E. Li
  • Yoshihisa Fujii

Best Publications

  • EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency.

    Xiaohua Shen;Yingchun Liu;Yu Jung Hsu;Yuko Fujiwara

  • Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1

    Yuko Fujiwara;Carol P. Browne;Kerrianne Cunniff;Sabra C. Goff

  • Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression

    Carola A. Neumann;Daniela S. Krause;Christopher V. Carman;Shampa Das

  • BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

    Matthew C. Canver;Elenoe C. Smith;Falak Sher;Luca Pinello

  • The T Cell Leukemia Oncoprotein SCL/tal-1 Is Essential for Development of All Hematopoietic Lineages

    Catherine Porcher;Wojciech Swat;Wojciech Swat;Karen Rockwell;Yuko Fujiwara;Yuko Fujiwara

  • FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation

    Alice P Tsang;Jane E Visvader;C.Alexander Turner;Yuko Fujiwara;Yuko Fujiwara

  • Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells.

    Robert S Ohgami;Dean R Campagna;Eric L Greer;Brendan Antiochos

  • A lineage‐selective knockout establishes the critical role of transcription factor GATA‐1 in megakaryocyte growth and platelet development

    Ramesh A. Shivdasani;Yuko Fujiwara;Yuko Fujiwara;Yuko Fujiwara;Michael A. McDevitt;Stuart H. Orkin

  • A Critical Role for DNA End-Joining Proteins in Both Lymphogenesis and Neurogenesis

    Yijie Gao;Yi Sun;Karen M. Frank;Pieter Dikkes

  • A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs

    Jonghwan Kim;Andrew J. Woo;Jianlin Chu;Jonathan W. Snow

  • Targeted Deletion of a High-Affinity GATA-binding Site in the GATA-1 Promoter Leads to Selective Loss of the Eosinophil Lineage In Vivo

    Channing Yu;Alan B. Cantor;Haidi Yang;Carol Browne

  • An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level

    Daniel E. Bauer;Sophia C. Kamran;Sophia C. Kamran;Samuel Lessard;Jian Xu;Jian Xu

  • Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells.

    Hanno Hock;Melanie J. Hamblen;Melanie J. Hamblen;Heather M. Rooke;Heather M. Rooke;Jeffrey W. Schindler

  • Isolation of a DEAD-family protein gene that encodes a murine homolog of Drosophila vasa and its specific expression in germ cell lineage

    Yuko Fujiwara;Tohru Komiya;Hiromi Kawabata;Michio Sato

  • Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart.

    Sean M. Wu;Yuko Fujiwara;Yuko Fujiwara;Susan M. Cibulsky;David E. Clapham;David E. Clapham

  • Transferrin receptor is necessary for development of erythrocytes and the nervous system

    Joanne E. Levy;Ou Jin;Yuko Fujiwara;Frank Kuo

  • FOG-2, a Cofactor for GATA Transcription Factors, Is Essential for Heart Morphogenesis and Development of Coronary Vessels from Epicardium

    Sergei G Tevosian;Anne E Deconinck;Makoto Tanaka;Martina Schinke

  • Germline gain-of-function mutations in RAF1 cause Noonan syndrome

    M Abdur Razzaque;Tsutomu Nishizawa;Yuta Komoike;Yuta Komoike;Hisato Yagi

  • Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver

    Hiromi Gunshin;Yuko Fujiwara;Angel O. Custodio;Cristina DiRenzo

  • A role for the C3a anaphylatoxin receptor in the effector phase of asthma

    Alison A. Humbles;Bao Lu;Christy A. Nilsson;Craig Lilly

Frequent Co-Authors

Stuart H. Orkin
Stuart H. Orkin Harvard University
Gabor Tigyi
Gabor Tigyi University of Tennessee Health Science Center
Guo-Cheng Yuan
Guo-Cheng Yuan Icahn School of Medicine at Mount Sinai
Duane D. Miller
Duane D. Miller University of Tennessee Health Science Center
Daniel E. Bauer
Daniel E. Bauer Harvard University
George Q. Daley
George Q. Daley Boston Children's Hospital
Frederick W. Alt
Frederick W. Alt Boston Children's Hospital
Roderick T. Bronson
Roderick T. Bronson Harvard University
Jane E. Visvader
Jane E. Visvader Walter and Eliza Hall Institute of Medical Research
Konrad Hochedlinger
Konrad Hochedlinger Harvard University

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