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Vijay G. Sankaran

Vijay G. Sankaran

D-Index & Metrics

Genetics

D-Index
67
Citations
22521
World Ranking
2502
National Ranking
1119

Overview

Vijay G. Sankaran is affiliated with Harvard University in the United States. Their research primarily focuses on fields related to biochemistry, genetics, and molecular biology, with substantial work in medicine. Within these disciplines, they concentrate on subfields including molecular biology, genetics, hematology, immunology, and cancer research.

The scientist's work spans various topics such as single-cell and spatial transcriptomics, epigenetics and DNA methylation, acute myeloid leukemia research, genetic associations and epidemiology, cancer genomics and diagnostics, hemoglobinopathies and related disorders, and genomics and rare diseases.

Vijay G. Sankaran has contributed to numerous publications across several venues, with frequent appearances in bioRxiv (Cold Spring Harbor Laboratory), Blood, Cell, UNC Libraries, and Nature Communications.

Among their recent papers are:

  • Mapping the human genetic architecture of COVID-19 (2021, Nature)
  • Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells (2021, Nature Biotechnology)
  • Mapping transcriptomic vector fields of single cells (2022, Cell)
  • Coronavirus disease 2019 in patients with inborn errors of immunity: An international study (2020, Journal of Allergy and Clinical Immunology)
  • Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling (2020, Nature Biotechnology)

They have collaborated frequently with Lara Wahlster, Laura M. Raffield, Richard A. Voit, Caleb A. Lareau, and Jeffrey M. Verboon.

Best Publications

  • Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific Repressor BCL11A

    Vijay G. Sankaran;Tobias F. Menne;Jian Xu;Thomas E. Akie

  • Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of β-thalassemia

    Manuela Uda;Renzo Galanello;Serena Sanna;Guillaume Lettre;Guillaume Lettre

  • Inherited causes of clonal haematopoiesis in 97,691 whole genomes.

    Alexander G Bick;Joshua S Weinstock;Satish K Nandakumar;Satish K Nandakumar;Charles P Fulco;Charles P Fulco

  • The polygenic and monogenic basis of blood traits and diseases

    Dragana Vuckovic;Erik L. Bao;Parsa Akbari;Caleb A. Lareau

  • Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.

    Ming-Huei Chen;Laura M Raffield;Abdou Mousas;Saori Sakaue

  • DNA polymorphisms at the BCL11A, HBS1L-MYB, and β-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

    Guillaume Lettre;Vijay G. Sankaran;Marcos André C. Bezerra;Aderson S. Araújo

  • Developmental and species-divergent globin switching are driven by BCL11A

    Vijay G. Sankaran;Jian Xu;Tobias Ragoczy;Gregory C. Ippolito

  • Transcriptional silencing of γ-globin by BCL11A involves long-range interactions and cooperation with SOX6

    Jian Xu;Vijay G. Sankaran;Min Ni;Min Ni;Tobias F. Menne

  • Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics.

    Leif S. Ludwig;Leif S. Ludwig;Caleb A. Lareau;Jacob C. Ulirsch;Elena Christian

  • Structural Basis for Discrimination of 3-Phosphoinositides by Pleckstrin Homology Domains

    Kathryn M. Ferguson;Jennifer M. Kavran;Vijay G. Sankaran;Emmanuel Fournier

  • Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

    Carl R. Walkley;Rameez Qudsi;Vijay G. Sankaran;Jennifer A. Perry

  • Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia

    Vijay G. Sankaran;Roxanne Ghazvinian;Ron Do;Prathapan Thiru

  • Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.

    Jian Xu;Cong Peng;Vijay G. Sankaran;Vijay G. Sankaran;Zhen Shao

  • The Switch from Fetal to Adult Hemoglobin

    Vijay G. Sankaran;Vijay G. Sankaran;Vijay G. Sankaran;Stuart H. Orkin;Stuart H. Orkin;Stuart H. Orkin

  • Coronavirus Disease 2019 in patients with inborn errors of immunity: an international study.

    Isabelle Meyts;Giorgia Bucciol;Isabella Quinti;Bénédicte Neven

  • Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis

    Rajiv K. Khajuria;Rajiv K. Khajuria;Rajiv K. Khajuria;Mathias Munschauer;Jacob C. Ulirsch;Jacob C. Ulirsch;Claudia Fiorini;Claudia Fiorini

  • Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells

    Eleni P. Mimitou;Caleb A. Lareau;Kelvin Y. Chen;Kelvin Y. Chen;Andre L. Zorzetto-Fernandes

  • Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits

    Jacob C. Ulirsch;Satish K. Nandakumar;Satish K. Nandakumar;Li Wang;Felix C. Giani

  • Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation

    Geneviève Galarneau;Cameron D Palmer;Cameron D Palmer;Vijay G Sankaran;Vijay G Sankaran;Stuart H Orkin;Stuart H Orkin;Stuart H Orkin

  • The Polygenic and Monogenic Basis of Blood Traits and Diseases

    Dragana Vuckovic;Dragana Vuckovic;Erik L. Bao;Erik L. Bao;Parsa Akbari;Caleb A. Lareau;Caleb A. Lareau

Frequent Co-Authors

Stuart H. Orkin
Stuart H. Orkin Harvard University
Eric S. Lander
Eric S. Lander Broad Institute
Guillaume Lettre
Guillaume Lettre Montreal Heart Institute
Alexander P. Reiner
Alexander P. Reiner University of Washington
Joel N. Hirschhorn
Joel N. Hirschhorn Boston Children's Hospital
Aviv Regev
Aviv Regev Genentech
Benjamin L. Ebert
Benjamin L. Ebert Harvard University
Jesse M. Engreitz
Jesse M. Engreitz Stanford University
Carl R. Walkley
Carl R. Walkley Hudson Institute of Medical Research
Sekar Kathiresan
Sekar Kathiresan Harvard University

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