D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics D-index 50 Citations 11,416 164 World Ranking 3180 National Ranking 1384

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Mutation
  • Genetics

The scientist’s investigation covers issues in Fetal hemoglobin, Genetics, Immunology, Regulation of gene expression and Gene. Vijay G. Sankaran focuses mostly in the field of Fetal hemoglobin, narrowing it down to matters related to Disease and, in some cases, Bioinformatics and Anemia. His Genetics study integrates concerns from other disciplines, such as Hereditary persistence of fetal hemoglobin and Cancer research.

The Immunology study combines topics in areas such as Fetal haemoglobin, Carrier protein, Developmental physiology and Neuroscience. His study in Regulation of gene expression is interdisciplinary in nature, drawing from both Osteosarcoma, Gene expression profiling, Chromatin immunoprecipitation, Gene silencing and Genetically modified mouse. His biological study deals with issues like Molecular biology, which deal with fields such as Gene cluster, Repressor, RNA interference, Exome and Exome sequencing.

His most cited work include:

  • Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific Repressor BCL11A (604 citations)
  • Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of β-thalassemia (462 citations)
  • DNA polymorphisms at the BCL11A, HBS1L-MYB, and β-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease (412 citations)

What are the main themes of his work throughout his whole career to date?

Genetics, Cell biology, Haematopoiesis, Erythropoiesis and Fetal hemoglobin are his primary areas of study. Genetics is a component of his Gene, Genome-wide association study, Blood cell, Locus and Transcription factor studies. His Cell biology research includes elements of Translation, microRNA, Cellular differentiation and Ribosomal protein.

CD34 is closely connected to Progenitor cell in his research, which is encompassed under the umbrella topic of Haematopoiesis. His Fetal hemoglobin study combines topics from a wide range of disciplines, such as Thalassemia, Hemoglobin, Immunology, Disease and Gene silencing. His work focuses on many connections between Immunology and other disciplines, such as Anemia, that overlap with his field of interest in Diamond–Blackfan anemia.

He most often published in these fields:

  • Genetics (50.19%)
  • Cell biology (45.59%)
  • Haematopoiesis (44.44%)

What were the highlights of his more recent work (between 2019-2021)?

  • Computational biology (30.27%)
  • Haematopoiesis (44.44%)
  • Cell (16.09%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Computational biology, Haematopoiesis, Cell, Stem cell and Cell biology. The concepts of his Computational biology study are interwoven with issues in Genome-wide association study, Phenotype, Gene, Epigenomics and Cell type. Genome-wide association study is a subfield of Genetics that he explores.

His work carried out in the field of Haematopoiesis brings together such families of science as Published Erratum, GTPase, Progenitor cell, Erythropoiesis and Genome. Vijay G. Sankaran has included themes like Lineage, Transcriptome, Mitochondrial DNA, Chromatin and Clonal hematopoiesis in his Cell study. His studies in Cell biology integrate themes in fields like Protein biosynthesis, Translation, Messenger RNA, microRNA and Ribosome.

Between 2019 and 2021, his most popular works were:

  • A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection. (72 citations)
  • Coronavirus Disease 2019 in patients with inborn errors of immunity: an international study. (39 citations)
  • Coronavirus Disease 2019 in patients with inborn errors of immunity: an international study. (39 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Mutation
  • Genetics

His primary scientific interests are in Genetics, Computational biology, Genome-wide association study, Blood cell and Genetic architecture. His study in Somatic cell, Stem cell and Haematopoiesis is carried out as part of his Genetics studies. His Somatic cell study incorporates themes from Locus, Human genetics, Germline and Genetic variation.

He has researched Genetic variation in several fields, including Disease and Immunology. His research integrates issues of Chromatin, Cell, Lineage commitment and Mitochondrial DNA in his study of Computational biology. His Blood cell research is multidisciplinary, incorporating perspectives in Allele and Mendelian inheritance.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific Repressor BCL11A

Vijay G. Sankaran;Tobias F. Menne;Jian Xu;Thomas E. Akie.
Science (2008)

909 Citations

Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of β-thalassemia

Manuela Uda;Renzo Galanello;Serena Sanna;Guillaume Lettre;Guillaume Lettre.
Proceedings of the National Academy of Sciences of the United States of America (2008)

677 Citations

DNA polymorphisms at the BCL11A, HBS1L-MYB, and β-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

Guillaume Lettre;Vijay G. Sankaran;Marcos André C. Bezerra;Aderson S. Araújo.
Proceedings of the National Academy of Sciences of the United States of America (2008)

601 Citations

Developmental and species-divergent globin switching are driven by BCL11A

Vijay G. Sankaran;Jian Xu;Tobias Ragoczy;Gregory C. Ippolito.
Nature (2009)

430 Citations

Transcriptional silencing of γ-globin by BCL11A involves long-range interactions and cooperation with SOX6

Jian Xu;Vijay G. Sankaran;Min Ni;Min Ni;Tobias F. Menne.
Genes & Development (2010)

417 Citations

Structural Basis for Discrimination of 3-Phosphoinositides by Pleckstrin Homology Domains

Kathryn M. Ferguson;Jennifer M. Kavran;Vijay G. Sankaran;Emmanuel Fournier.
Molecular Cell (2000)

409 Citations

Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

Carl R. Walkley;Rameez Qudsi;Vijay G. Sankaran;Jennifer A. Perry.
Genes & Development (2008)

361 Citations

Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia

Vijay G. Sankaran;Roxanne Ghazvinian;Ron Do;Prathapan Thiru.
Journal of Clinical Investigation (2012)

348 Citations

Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.

Jian Xu;Cong Peng;Vijay G. Sankaran;Vijay G. Sankaran;Zhen Shao.
Science (2011)

325 Citations

The Switch from Fetal to Adult Hemoglobin

Vijay G. Sankaran;Vijay G. Sankaran;Vijay G. Sankaran;Stuart H. Orkin;Stuart H. Orkin;Stuart H. Orkin.
Cold Spring Harbor Perspectives in Medicine (2013)

283 Citations

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