World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
43
Citations
18269
World Ranking
19341
National Ranking
7897

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genetics

His main research concerns Genetics, RNA, Gene expression, Regulation of gene expression and Cell biology. His work on RNA splicing, Transcription, Chromatin and Nucleosome as part of general Genetics research is frequently linked to Loop, bridging the gap between disciplines. The RNA study which covers Computational biology that intersects with X-inactivation.

His Gene expression research is within the category of Gene. Jesse M. Engreitz has researched Regulation of gene expression in several fields, including Histone code, CTCF, Compartment, Cohesin and Histone. His research in Cell biology intersects with topics in Epitranscriptomics, Transcriptome, Small nucleolar RNA and MRNA modification.

His most cited work include:

  • Cohesin Loss Eliminates All Loop Domains (763 citations)
  • The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome (675 citations)
  • The Lin28/let-7 axis regulates glucose metabolism (621 citations)

What are the main themes of his work throughout his whole career to date?

Jesse M. Engreitz focuses on Computational biology, Gene, Genetics, Genome and Regulation of gene expression. Jesse M. Engreitz has included themes like RNA, Chromatin and Human genetic variation in his Computational biology study. His Non-coding RNA and Small nuclear RNA study in the realm of RNA interacts with subjects such as Amplicon.

Jesse M. Engreitz interconnects Antisense RNA and Cell biology in the investigation of issues within Non-coding RNA. His research investigates the connection between Genome and topics such as CRISPR that intersect with problems in Regulatory sequence. His Regulation of gene expression research includes elements of Histone and Functional genomics.

He most often published in these fields:

  • Computational biology (71.30%)
  • Gene (65.74%)
  • Genetics (59.26%)

What were the highlights of his more recent work (between 2019-2021)?

  • Gene (65.74%)
  • Computational biology (71.30%)
  • Genome-wide association study (34.26%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Gene, Computational biology, Genome-wide association study, Genetic association and Enhancer. His Gene study often links to related topics such as Cell biology. His studies deal with areas such as SNP, Regulation of gene expression, Genome and CRISPR as well as Computational biology.

The various areas that Jesse M. Engreitz examines in his Regulation of gene expression study include RNA, Hybridization probe and Intron. The Enhancer study combines topics in areas such as SWI/SNF, Clinical phenotype and Function. His research on Somatic cell concerns the broader Genetics.

Between 2019 and 2021, his most popular works were:

  • Inherited causes of clonal haematopoiesis in 97,691 whole genomes. (35 citations)
  • Inherited causes of clonal haematopoiesis in 97,691 whole genomes. (35 citations)
  • Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features (31 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genetics

Jesse M. Engreitz focuses on Genetic association, Genome-wide association study, Gene, Genetic variation and Locus. As part of his studies on Gene, he often connects relevant subjects like Computational biology. The concepts of his Computational biology study are interwoven with issues in Biological pathway, Gene prioritization, Novel gene and CRISPR.

To a larger extent, Jesse M. Engreitz studies Genetics with the aim of understanding Genetic variation. His Genetics research is mostly focused on the topic Haematopoiesis. His Locus research is multidisciplinary, relying on both Somatic cell, Linkage disequilibrium, Germline, Stem cell and Human genetics.

Best Publications

  • Cohesin Loss Eliminates All Loop Domains

    Suhas S.P. Rao;Suhas S.P. Rao;Su Chen Huang;Brian Glenn St Hilaire;Brian Glenn St Hilaire;Jesse M. Engreitz

  • Local regulation of gene expression by lncRNA promoters, transcription and splicing

    Jesse M. Engreitz;Jesse M. Engreitz;Jenna E. Haines;Elizabeth M. Perez;Glen Munson

  • The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome

    Jesse M. Engreitz;Amy Pandya-Jones;Patrick McDonel;Alexander Shishkin

  • The Lin28/let-7 axis regulates glucose metabolism

    Hao Zhu;Ng Shyh-Chang;Ayellet V. Segrè;Ayellet V. Segrè;Gen Shinoda

  • Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA

    Schraga Schwartz;Douglas A. Bernstein;Maxwell R. Mumbach;Marko Jovanovic

  • Activity-by-contact model of enhancer-promoter regulation from thousands of CRISPR perturbations.

    Charles P. Fulco;Charles P. Fulco;Joseph Nasser;Thouis R. Jones;Glen Munson

  • Genome-wide enhancer maps link risk variants to disease genes

    Joseph Nasser;Drew T. Bergman;Charles P. Fulco;Charles P. Fulco;Philine Guckelberger;Philine Guckelberger

  • Inherited causes of clonal haematopoiesis in 97,691 whole genomes.

    Alexander G Bick;Joshua S Weinstock;Satish K Nandakumar;Satish K Nandakumar;Charles P Fulco;Charles P Fulco

  • COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets.

    Toni M. Delorey;Carly G. K. Ziegler;Graham Heimberg;Rachelly Normand

  • Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre

    Ezgi Hacisuleyman;Loyal A Goff;Cole Trapnell;Adam Williams

  • Systematic mapping of functional enhancer-promoter connections with CRISPR interference

    Charles P. Fulco;Charles P. Fulco;Mathias Munschauer;Rockwell Anyoha;Glen Munson

  • Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression

    Jesse M. Engreitz;Noah Ollikainen;Mitchell Guttman

  • Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses

    Kelly D Moynihan;Cary F Opel;Gregory L Szeto;Alice Tzeng

  • RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites.

    Jesse M. Engreitz;Jesse M. Engreitz;Klara Sirokman;Patrick McDonel;Alexander A. Shishkin

  • A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression

    Rajat M. Gupta;Joseph Hadaya;Aditi Trehan;Seyedeh M. Zekavat

  • Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood

    Julia Joung;Jesse M. Engreitz;Silvana Konermann;Omar O. Abudayyeh

  • Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis

    Rajiv K. Khajuria;Rajiv K. Khajuria;Rajiv K. Khajuria;Mathias Munschauer;Jacob C. Ulirsch;Jacob C. Ulirsch;Claudia Fiorini;Claudia Fiorini

  • The NORAD lncRNA assembles a topoisomerase complex critical for genome stability.

    Mathias Munschauer;Celina T. Nguyen;Klara Sirokman;Christina R. Hartigan

  • Recurrent and functional regulatory mutations in breast cancer

    Esther Rheinbay;Esther Rheinbay;Prasanna Parasuraman;Jonna Grimsby;Grace Tiao

  • Systematic dissection of genomic features determining transcription factor binding and enhancer function

    Sharon R Grossman;Sharon R Grossman;Sharon R Grossman;Xiaolan Zhang;Li Wang;Jesse Engreitz;Jesse Engreitz

Frequent Co-Authors

Eric S. Lander
Eric S. Lander Broad Institute
Alkes L. Price
Alkes L. Price Harvard University
Sekar Kathiresan
Sekar Kathiresan Harvard University
Mitchell Guttman
Mitchell Guttman California Institute of Technology
Vijay G. Sankaran
Vijay G. Sankaran Harvard University
Aviv Regev
Aviv Regev Genentech
Andrea Ganna
Andrea Ganna Massachusetts General Hospital
Nir Hacohen
Nir Hacohen Harvard University
Braxton D. Mitchell
Braxton D. Mitchell University of Maryland, Baltimore

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