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Emma Whitelaw

Emma Whitelaw

QIMR Berghofer Medical Research Institute
Australia

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • Genetics

Emma Whitelaw focuses on Genetics, Epigenetics, DNA methylation, Gene and Reprogramming. All of her Genetics and Genome, Offspring, Gene silencing, Chromatin and Transgene investigations are sub-components of the entire Genetics study. Her study in Chromatin is interdisciplinary in nature, drawing from both Genetically modified mouse and Gene expression.

Her research in Transgene intersects with topics in Genetic heterogeneity, Dominance and Genomic imprinting. Her studies in Epigenetics integrate themes in fields like Phenotype, Allele, Genotype, Locus and Inheritance. Her Inheritance research focuses on subjects like Evolutionary biology, which are linked to Germline, Epigenesis and Adaptation.

Her most cited work include:

  • Repeat-induced gene silencing in mammals. (821 citations)
  • Transgenerational inheritance of epigenetic states at the murine AxinFu allele occurs after maternal and paternal transmission (542 citations)
  • Understanding transgenerational epigenetic inheritance via the gametes in mammals (500 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of investigation include Genetics, Epigenetics, Gene, DNA methylation and Phenotype. Her study in Allele, Gene silencing, Transgene, Epigenesis and Locus is carried out as part of her Genetics studies. Her studies deal with areas such as Mutation, Gene expression and Variegation as well as Transgene.

Her Epigenetics research is multidisciplinary, relying on both Reprogramming, Genome, Chromatin, Inheritance and Genotype. Emma Whitelaw usually deals with Gene and limits it to topics linked to Offspring and Endocrinology. Her DNA methylation research includes themes of Molecular biology, Histone and X chromosome.

She most often published in these fields:

  • Genetics (83.33%)
  • Epigenetics (65.38%)
  • Gene (39.74%)

What were the highlights of her more recent work (between 2010-2015)?

  • Genetics (83.33%)
  • Epigenetics (65.38%)
  • DNA methylation (37.18%)

In recent papers she was focusing on the following fields of study:

Genetics, Epigenetics, DNA methylation, Gene and Phenotype are her primary areas of study. Her study looks at the relationship between Epigenetics and topics such as Enhancer, which overlap with Deep sequencing. DNA methylation is often connected to Chromatin in her work.

Her study in the fields of Microarray, Germline and Copy-number variation under the domain of Gene overlaps with other disciplines such as Behavioral medicine. Her work deals with themes such as Endocrinology, Retrotransposon and Genotype, which intersect with Phenotype. Her research investigates the connection between Genomic imprinting and topics such as X chromosome that intersect with issues in Allele.

Between 2010 and 2015, her most popular works were:

  • Understanding transgenerational epigenetic inheritance via the gametes in mammals (500 citations)
  • Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes (158 citations)
  • Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies (57 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genetics

Emma Whitelaw mainly investigates Genetics, Epigenetics, DNA methylation, Allele and Chromatin. Her study deals with a combination of Genetics and Schizophrenia. The concepts of her Epigenetics study are interwoven with issues in Regulation of gene expression, Psychological repression, Transcriptional regulation and Histone.

The various areas that she examines in her Chromatin study include DNA hypomethylation, Inheritance, Structural inheritance, DNA sequencing and Epigenome. Her biological study spans a wide range of topics, including Meiosis, Wild type, Chromosome, Y chromosome and X chromosome. Her Transgene study combines topics from a wide range of disciplines, such as Phenotype, Variegation, Genotype, Mutagenesis and Gene silencing.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Repeat-induced gene silencing in mammals.

David Garrick;Steven Fiering;David I.K. Martin;Emma Whitelaw.
Nature Genetics (1998)

900 Citations

Transgenerational inheritance of epigenetic states at the murine AxinFu allele occurs after maternal and paternal transmission

Vardhman K. Rakyan;Suyinn Chong;Marnie E. Champ;Peter C. Cuthbert.
Proceedings of the National Academy of Sciences of the United States of America (2003)

703 Citations

Understanding transgenerational epigenetic inheritance via the gametes in mammals

Lucia Daxinger;Emma Whitelaw.
Nature Reviews Genetics (2012)

689 Citations

Transgenerational Epigenetic Effects

Neil A Youngson;Emma Whitelaw.
Annual Review of Genomics and Human Genetics (2008)

630 Citations

Metastable epialleles in mammals

Vardhman K Rakyan;Marnie E Blewitt;Riki Druker;Jost I Preis.
Trends in Genetics (2002)

511 Citations

Retrotransposons as epigenetic mediators of phenotypic variation in mammals.

Emma Whitelaw;David I.K. Martin.
Nature Genetics (2001)

466 Citations

SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation.

Marnie E Blewitt;Anne-Valerie Gendrel;Zhenyi Pang;Duncan B Sparrow.
Nature Genetics (2008)

360 Citations

Maternal ethanol consumption alters the epigenotype and the phenotype of offspring in a mouse model.

Nina Kaminen-Ahola;Arttu Ahola;Arttu Ahola;Murat Maga;Kylie-Ann Mallitt.
PLOS Genetics (2010)

316 Citations

Transgenerational epigenetic inheritance: More questions than answers

Lucia Daxinger;Emma Whitelaw.
Genome Research (2010)

294 Citations

Epigenetic germline inheritance.

Suyinn Chong;Emma Whitelaw.
Current Opinion in Genetics & Development (2004)

284 Citations

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