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Biology and Biochemistry

D-Index
55
Citations
11684
World Ranking
14993
National Ranking
6273

Overview

David H.K. Chui is affiliated with Boston University in the United States. Their research primarily lies within the field of Medicine, with a substantial focus on Genetics and Hematology. Additional subfields of study include Physiology, Pulmonary and Respiratory Medicine, and Molecular Biology.

Their work covers a range of topics, including:

  • Hemoglobinopathies and Related Disorders
  • Blood groups and transfusion
  • Iron Metabolism and Disorders
  • Genomics and Rare Diseases
  • Erythrocyte Function and Pathophysiology
  • Cystic Fibrosis Research Advances
  • RNA modifications and cancer

Chui has been involved in publications across multiple venues, such as:

  • Nucleic Acids Research
  • British Journal of Haematology
  • Expert Review of Hematology
  • Pediatric Blood & Cancer
  • Hemoglobin

Notable recent papers include:

  • Clinically relevant updates of the HbVar database of human hemoglobin variants and thalassemia mutations (2020) published in Nucleic Acids Research
  • Pharmacologic induction of PGC-1α stimulates fetal haemoglobin gene expression (2022) published in British Journal of Haematology
  • Strategies to improve pharmacogenomic-guided treatment options for patients with β-hemoglobinopathies (2021) published in Expert Review of Hematology
  • Clinical phenotypes of three children with sickle cell disease caused by HbS/Sicilian (δβ)0-thalassemia deletion (2022) published in American Journal of Hematology
  • Transient neonatal hemolytic anemia due to the novel gamma globin gene mutation HBG2:C.290T>C, p.Leu97Pro (hemoglobin Wareham) (2022) published in Pediatric Blood & Cancer

Frequent co-authors in their recent work include:

  • Ross C. Hardison
  • George P. Patrinos
  • Yanan Sun
  • Martin H. Steinberg
  • Shuaiying Cui

Best Publications

  • Fetal hemoglobin in sickle cell anemia

    Idowu Akinsheye;Abdulrahman Alsultan;Nadia Solovieff;Duyen Ngo

  • HbVar: A relational database of human hemoglobin variants and thalassemia mutations at the globin gene server.

    Ross C. Hardison;David H.K. Chui;Belinda Giardine;Cathy Riemer

  • IMPROVEMENTS IN THE HBVAR DATABASE OF HUMAN HEMOGLOBIN VARIANTS AND THALASSEMIA MUTATIONS FOR POPULATION AND SEQUENCE VARIATION STUDIES

    George P. Patrinos;Belinda Giardine;Cathy Riemer;Webb Miller

  • Hemoglobin H disease: not necessarily a benign disorder

    David H K Chui;Suthat Fucharoen;Vivian Chan

  • Prenatal exclusion of β thalassaemia major by examination of maternal plasma

    Rossa W.K. Chiu;Tze K. Lau;Tse N. Leung;Katherine C.K. Chow

  • Hydrops Fetalis Caused by α-Thalassemia: An Emerging Health Care Problem

    David H.K. Chui;John S. Waye

  • Prevalence and genotypes of α- and β-thalassemia carriers in Hong Kong : Implications for population screening

    Yu-Lung Lau;Li-Chong Chan;Yuk-Yin A. Chan;Shau-Yin Ha

  • MS analysis of single-nucleotide differences in circulating nucleic acids: Application to noninvasive prenatal diagnosis.

    Chunming Ding;Rossa W.K. Chiu;Tze K. Lau;Tse N. Leung

  • HbVar database of human hemoglobin variants and thalassemia mutations: 2007 update.

    Belinda Giardine;Sjozef van Baal;Polynikis Kaimakis;Cathy Riemer

  • Properties of the earliest clonogenic hemopoietic precursors to appear in the developing murine yolk sac.

    P. M. C. Wong;S. W. Chung;D. H. K. Chui;C. J. Eaves

  • Fetal hemoglobin in sickle cell anemia: a glass half full?

    Martin H. Steinberg;David H.K. Chui;George J. Dover;Paola Sebastiani

  • Hemoglobin ontogeny during normal mouse fetal development.

    Timothy W. Brotherton;David H. K. Chui;Jack Gauldie;Margaret Patterson

  • BCL11A is a major HbF quantitative trait locus in three different populations with β-hemoglobinopathies ☆

    Amanda E. Sedgewick;Nadia Timofeev;Paola Sebastiani;Jason C.C. So

  • An ultrastructural study of early morphogenetic events during the establishment of fetal hepatic erythropoiesis.

    Richard A. Rifkind;David Chui;Hazel Epler

  • Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach

    Belinda Giardine;Joseph Borg;Joseph Borg;Douglas R Higgs;Kenneth R Peterson

  • Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster

    Nadia Solovieff;Jacqueline N. Milton;Stephen W. Hartley;Richard Sherva

  • The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation.

    Brenden W. Smith;Brenden W. Smith;Sarah S. Rozelle;Sarah S. Rozelle;Amy Leung;Amy Leung;Jessalyn Ubellacker

  • Clinical features and molecular analysis of the alpha thalassemia/mental retardation syndromes. II. Cases without detectable abnormality of the alpha globin complex.

    A. O. M. Wilkie;H. C. Zeitlin;R. H. Lindenbaum;V. J. Buckle

  • A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression

    John J. Farrell;Richard M. Sherva;Zhi-yi Chen;Hong-yuan Luo

  • Imputation of missing genotypes: an empirical evaluation of IMPUTE

    Zhenming Zhao;Nadia Timofeev;Stephen W. Hartley;David H. K. Chui

Frequent Co-Authors

Martin H. Steinberg
Martin H. Steinberg Boston University
John S. Waye
John S. Waye McMaster University
Clinton T. Baldwin
Clinton T. Baldwin Boston University
Lindsay A. Farrer
Lindsay A. Farrer Boston University
Ross C. Hardison
Ross C. Hardison Pennsylvania State University
Nancy F. Olivieri
Nancy F. Olivieri University of Toronto
Webb Miller
Webb Miller Pennsylvania State University
George P. Patrinos
George P. Patrinos University of Patras
Bernard G. Forget
Bernard G. Forget Yale University
Gustavo Mostoslavsky
Gustavo Mostoslavsky Boston University

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