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Genetics

D-Index
59
Citations
14842
World Ranking
3226
National Ranking
396

Overview

Richard J. Gibbons is affiliated with the University of Oxford in the United Kingdom. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology as the major subfield alongside contributions to Physiology, Genetics, Cancer Research, and Immunology.

The scientist's work covers several key topics, including:

  • Genomics and Chromatin Dynamics
  • Telomeres, Telomerase, and Senescence
  • RNA Research and Splicing
  • RNA Interference and Gene Delivery
  • Advanced biosensing and bioanalysis techniques
  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering

Richard J. Gibbons has published research in multiple scientific venues, with frequent publications in:

  • Nature Communications
  • Nucleic Acids Research
  • Blood
  • Genes
  • Journal of Medical Genetics

Recent papers by this researcher include:

  • The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin (2022, Nature Communications)
  • A gain-of-function single nucleotide variant creates a new promoter which acts as an orientation-dependent enhancer-blocker (2021, Nature Communications)
  • Induction of the alternative lengthening of telomeres pathway by trapping of proteins on DNA (2023, Nucleic Acids Research)
  • An evolutionarily ancient mechanism for regulation of hemoglobin expression in vertebrate red cells (2020, Blood)
  • Genetic and functional insights into CDA-I prevalence and pathogenesis (2020, Journal of Medical Genetics)

They have worked collaboratively with several frequent co-authors, including Douglas R. Higgs, Damien J. Downes, Jill M. Brown, Jim R. Hughes, and Anna M. Rose. These collaborations highlight a network of research partnerships predominantly centered on molecular and genetic biology topics.

Best Publications

  • Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

    Aaron D. Goldberg;Laura A. Banaszynski;Kyung Min Noh;Peter W. Lewis

  • A systematic genome-wide analysis of zebrafish protein-coding gene function

    Ross N. W. Kettleborough;Elisabeth M. Busch-Nentwich;Steven A. Harvey;Christopher M. Dooley

  • Mutations in a Putative Global Transcriptional Regulator Cause X-linked Mental Retardation With Alpha-Thalassemia (ATR-X Syndrome)

    Richard J Gibbons;David J Picketts;Laurent Villard;Douglas R Higgs

  • Mutations in ATRX , encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation

    Richard J. Gibbons;Tarra L. McDowell;Sundhya Raman;Delia M. O'Rourke

  • Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment.

    Jim R Hughes;Nigel Roberts;Simon McGowan;Deborah Hay

  • ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner

    Martin J. Law;Karen M. Lower;Hsiao P.J. Voon;Jim R. Hughes

  • The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies

    Yutong Xue;Richard Gibbons;Zhijiang Yan;Dafeng Yang

  • A Regulatory SNP Causes a Human Genetic Disease by Creating a New Transcriptional Promoter

    Marco De Gobbi;Vip Viprakasit;Jim R Hughes;Chris Fisher

  • Genetic dissection of the α-globin super-enhancer in vivo

    Deborah Hay;Jim R. Hughes;Christian Babbs;James O.J. Davies

  • The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription

    Rebekka A. Schwab;Jadwiga Nieminuszczy;Fenil Shah;Jamie Langton

  • Intragenic Enhancers Act as Alternative Promoters

    Monika S. Kowalczyk;Jim R. Hughes;David Garrick;Magnus D. Lynch

  • Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX

    David Clynes;Clare Jelinska;Barbara Xella;Helena Ayyub

  • ATRX Encodes a Novel Member of the SNF2 Family of Proteins: Mutations Point to a Common Mechanism Underlying the ATR-X Syndrome

    David J. Picketts;Douglas R. Higgs;Satvinder Bachoo;Derek J. Blake

  • LOCALIZATION OF A PUTATIVE TRANSCRIPTIONAL REGULATOR (ATRX) AT PERICENTROMERIC HETEROCHROMATIN AND THE SHORT ARMS OF ACROCENTRIC CHROMOSOMES

    T. L. McDowell;R. J. Gibbons;H. Sutherland;D. M. O’Rourke

  • Molecular-clinical spectrum of the ATR-X syndrome.

    Richard J. Gibbons;Douglas R. Higgs

  • The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis

    Nathalie G. Bérubé;Marie Mangelsdorf;Magdalena Jagla;Jackie Vanderluit

  • Mutations in transcriptional regulator ATRX establish the functional significance of a PHD-like domain

    Richard J. Gibbons;Satvinder Bachoo;David J. Picketts;Salim Aftimos

  • An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment

    Magnus D Lynch;Andrew J H Smith;Andrew J H Smith;Marco De Gobbi;Maria Flenley

  • Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin

    Sebastian Eustermann;Ji-Chun Yang;Martin J Law;Rachel Amos

  • Loss of Atrx Affects Trophoblast Development and the Pattern of X-Inactivation in Extraembryonic Tissues

    David Garrick;Jackie A Sharpe;Ruth M. Arkell;Lorraine Dobbie

Frequent Co-Authors

Douglas R. Higgs
Douglas R. Higgs University of Oxford
James Hughes
James Hughes Emory University
David P. Steensma
David P. Steensma Harvard University
William G. Wood
William G. Wood University of Oxford
Veronica J. Buckle
Veronica J. Buckle University of Oxford
Stephen S. Taylor
Stephen S. Taylor University of Manchester
Jill Clayton-Smith
Jill Clayton-Smith University of Manchester
Julian Roy Sampson
Julian Roy Sampson Cardiff University
Andrew J.H. Smith
Andrew J.H. Smith University of Edinburgh
Andrew O.M. Wilkie
Andrew O.M. Wilkie University of Oxford

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Related Online Degrees & Career Pathways

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