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Microbiology

D-Index
58
Citations
10405
World Ranking
3473
National Ranking
1371

Overview

Yun C. Chang is affiliated with the National Institutes of Health in the United States. Their research primarily spans the field of Medicine, with a focus on subfields such as Epidemiology, Infectious Diseases, Small Animals, Molecular Biology, and Plant Science.

The main topics of Yun C. Chang's work include:

  • Fungal Infections and Studies
  • Antifungal resistance and susceptibility
  • Nail Diseases and Treatments
  • Infectious Diseases and Mycology
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Plant Pathogens and Fungal Diseases
  • Plant-Microbe Interactions and Immunity

Several recent papers authored or co-authored by Yun C. Chang illustrate these research interests:

  • Moderate levels of 5-fluorocytosine cause the emergence of high frequency resistance in cryptococci (2021, Nature Communications)
  • Cryptococcus gattii Species Complex as an Opportunistic Pathogen: Underlying Medical Conditions Associated with the Infection (2021, mBio)
  • In Vivo Efficacy of Olorofim against Systemic Scedosporiosis and Lomentosporiosis (2021, Antimicrobial Agents and Chemotherapy)
  • Antifungal Susceptibility Profiles of Olorofim (Formerly F901318) and Currently Available Systemic Antifungals against Mold and Yeast Phases of Talaromyces marneffei (2021, Antimicrobial Agents and Chemotherapy)
  • Solanum lycopersicum derived exosome-like nanovesicles alleviate restenosis after vascular injury through the Keap1/Nrf2 pathway (2024, Food & Function)

Yun C. Chang publishes frequently in several scientific venues, including:

  • mBio
  • Antimicrobial Agents and Chemotherapy
  • Medical Mycology
  • The Journal of Immunology
  • Nature Communications

The researcher collaborates regularly with several co-authors, some of whom have a notable number of joint publications. Frequent collaborators include:

  • Kyung J. Kwon-Chung
  • Michael J. Davis
  • Dong-Hoon Yang
  • Hechen Shen
  • Wenqing Gao

Best Publications

  • A developmentally regulated gene cluster involved in conidial pigment biosynthesis in Aspergillus fumigatus.

    Huei-Fung Tsai;Michael H. Wheeler;Yun C. Chang;K. J. Kwon-Chung

  • Cryptococcus neoformans overcomes stress of azole drugs by formation of disomy in specific multiple chromosomes.

    Edward Sionov;Hyeseung Lee;Yun C. Chang;Kyung J. Kwon-Chung

  • The Developmentally Regulated alb1 Gene of Aspergillus fumigatus: Its Role in Modulation of Conidial Morphology and Virulence

    Huei-Fung Tsai;Yun C. Chang;Ronald G. Washburn;Michael H. Wheeler

  • The Case for Adopting the "Species Complex" Nomenclature for the Etiologic Agents of Cryptococcosis.

    Kyung J. Kwon-Chung;John E. Bennett;Brian L. Wickes;Wieland Meyer

  • Cryptococcal Yeast Cells Invade the Central Nervous System via Transcellular Penetration of the Blood-Brain Barrier

    Yun C. Chang;Monique F. Stins;Michael J. McCaffery;Georgina F. Miller

  • The second capsule gene of cryptococcus neoformans, CAP64, is essential for virulence.

    Y C Chang;L A Penoyer;K J Kwon-Chung

  • Gliotoxin Is a Virulence Factor of Aspergillus fumigatus: gliP Deletion Attenuates Virulence in Mice Immunosuppressed with Hydrocortisone

    Janyce A. Sugui;Julian Pardo;Yun C. Chang;Kol A. Zarember

  • Isolation of the third capsule-associated gene, CAP60, required for virulence in Cryptococcus neoformans.

    Y. C. Chang;K. J. Kwon-Chung

  • Human Polymorphonuclear Leukocytes Inhibit Aspergillus fumigatus Conidial Growth by Lactoferrin-Mediated Iron Depletion

    Kol A. Zarember;Janyce A. Sugui;Yun C. Chang;Kyung J. Kwon-Chung

  • Cryptococcus neoformans induces alterations in the cytoskeleton of human brain microvascular endothelial cells.

    Steven H.M. Chen;Monique F. Stins;Sheng He Huang;Yu Hua Chen

  • Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans

    Yun C. Chang;Clara M. Bien;Hyeseung Lee;Peter J. Espenshade

  • Isolation, Characterization, and Localization of a Capsule-Associated Gene, CAP10, of Cryptococcus neoformans

    Y. C. Chang;K. J. Kwon-Chung

  • Identification of Aspergillus brlA response elements (BREs) by genetic selection in yeast.

    Yun C. Chang;William E. Timberlake

  • Agrobacterium tumefaciens-mediated transformation of Aspergillus fumigatus: an efficient tool for insertional mutagenesis and targeted gene disruption

    Janyce A. Sugui;Yun C. Chang;K. J. Kwon-Chung

  • Pentaketide melanin biosynthesis in Aspergillus fumigatus requires chain-length shortening of a heptaketide precursor.

    Huei-Fung Tsai;Isao Fujii;Akira Watanabe;Michael H. Wheeler

  • Cryptococcus neoformans STE12α Regulates Virulence but Is Not Essential for Mating

    Y.C. Chang;B.L. Wickes;G.F. Miller;L.A. Penoyer

  • Heteroresistance to Fluconazole in Cryptococcus neoformans Is Intrinsic and Associated with Virulence

    Edward Sionov;Yun C. Chang;H. Martin Garraffo;Kyung J. Kwon-Chung

  • Virulence of catalase-deficient aspergillus nidulans in p47(phox)-/- mice. Implications for fungal pathogenicity and host defense in chronic granulomatous disease.

    Y C Chang;B H Segal;S M Holland;G F Miller

  • Aspergillus fumigatus arp1 modulates conidial pigmentation and complement deposition

    Huei-Fung Tsai;Ronald G. Washburn;Yun C. Chang;K. J. Kwon-Chung

  • Cryptococcus neoformans CAP59 (or Cap59p) Is Involved in the Extracellular Trafficking of Capsular Glucuronoxylomannan

    Javier García-Rivera;Yun C. Chang;K. J. Kwon-Chung;Arturo Casadevall

  • The Primary Target Organ of Cryptococcus gattii Is Different from That of Cryptococcus neoformans in a Murine Model

    Popchai Ngamskulrungroj;Yun Chang;Edward Sionov;Kyung J. Kwon-Chung

Frequent Co-Authors

Kyung J. Kwon-Chung
Kyung J. Kwon-Chung National Institutes of Health
Hye Seung Lee
Hye Seung Lee Seoul National University Bundang Hospital
Brian L. Wickes
Brian L. Wickes The University of Texas Health Science Center at San Antonio
Michael Eckhaus
Michael Eckhaus National Institutes of Health
William C. Nierman
William C. Nierman J. Craig Venter Institute
John I. Gallin
John I. Gallin National Institutes of Health
John R. Perfect
John R. Perfect Duke University
Peter Walter
Peter Walter University of California, San Francisco
Wieland Meyer
Wieland Meyer Westerdijk Fungal Biodiversity Institute
Christina A. Cuomo
Christina A. Cuomo Broad Institute

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