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J. Andrew Alspaugh

J. Andrew Alspaugh

D-Index & Metrics

Microbiology

D-Index
46
Citations
7160
World Ranking
4926
National Ranking
1906

Overview

J. Andrew Alspaugh is affiliated with Duke University in the United States and has contributed extensively to the field of Medicine, with particular focus on Epidemiology, Infectious Diseases, and Molecular and Cell Biology. Their research primarily addresses fungal infections, antifungal resistance, and plant-microbe interactions.

The scientist's recent publications cover a range of topics within fungal biology and pathogenicity. Selected papers include:

  • Transposon mobilization in the human fungal pathogen Cryptococcus is mutagenic during infection and promotes drug resistance in vitro, 2020, Proceedings of the National Academy of Sciences
  • Erg6 affects membrane composition and virulence of the human fungal pathogen Cryptococcus neoformans, 2020, Fungal Genetics and Biology
  • Sterol-Response Pathways Mediate Alkaline Survival in Diverse Fungi, 2020, mBio
  • Length Specificity and Polymerization Mechanism of (1,3)-β-d-Glucan Synthase in Fungal Cell Wall Biosynthesis, 2020, Biochemistry
  • Human IgM Inhibits the Formation of Titan-Like Cells in Cryptococcus neoformans, 2020, Infection and Immunity

Their collaboration network includes frequent co-authors such as Connie B. Nichols, Calla L. Telzrow, Corinna Probst, Jacob T. Brooks, and Hannah Brown.

J. Andrew Alspaugh's work is regularly published in several scientific venues. These include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • mBio
  • PLoS Pathogens
  • Proceedings of the National Academy of Sciences
  • Infection and Immunity

The scientist's research topics can be detailed as follows:

  • Fungal Infections and Studies
  • Antifungal resistance and susceptibility
  • Plant-Microbe Interactions and Immunity
  • Plant Pathogens and Fungal Diseases
  • Nail Diseases and Treatments
  • Phytoplasmas and Hemiptera pathogens
  • Plant Disease Resistance and Genetics

Subfields of J. Andrew Alspaugh's work include:

  • Epidemiology
  • Infectious Diseases
  • Plant Science
  • Molecular Biology
  • Cell Biology

Best Publications

  • Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP

    J. Andrew Alspaugh;John R. Perfect;Joseph Heitman

  • The Cryptococcus neoformans capsule: a sword and a shield.

    Teresa R. O'Meara;J. Andrew Alspaugh

  • Cyclic AMP-dependent protein kinase controls virulence of the fungal pathogen Cryptococcus neoformans.

    Cletus A. D'Souza;J. Andrew Alspaugh;Changli Yue;Toshiaki Harashima

  • RAS1 regulates filamentation, mating and growth at high temperature of Cryptococcus neoformans.

    J. Andrew Alspaugh;Lora M. Cavallo;John R. Perfect;Joseph Heitman

  • Adenylyl Cyclase Functions Downstream of the Gα Protein Gpa1 and Controls Mating and Pathogenicity of Cryptococcus neoformans

    J. Andrew Alspaugh;Read Pukkila-Worley;Toshiaki Harashima;Lora M. Cavallo

  • Interaction of Cryptococcus neoformans Rim101 and protein kinase A regulates capsule.

    Teresa R. O'Meara;Diana Norton;Michael S. Price;Christie Hay

  • Gene Disruption by Biolistic Transformation in Serotype D Strains of Cryptococcus neoformans

    R. C. Davidson;M. C. Cruz;R. A. L. Sia;B. Allen

  • Transcriptional Network of Multiple Capsule and Melanin Genes Governed by the Cryptococcus neoformans Cyclic AMP Cascade

    Read Pukkila-Worley;Quincy D. Gerrald;Peter R. Kraus;Marie-Josée Boily

  • New Horizons in Antifungal Therapy

    Unknown

  • Inhibition of Cryptococcus neoformans replication by nitrogen oxides supports the role of these molecules as effectors of macrophage-mediated cytostasis

    Unknown

  • Differential Effects of Inhibiting Chitin and 1,3-β-d-Glucan Synthesis in Ras and Calcineurin Mutants of Aspergillus fumigatus

    Jarrod R. Fortwendel;Praveen Rao Juvvadi;Nadthanan Pinchai;B. Zachary Perfect

  • The STE12alpha homolog is required for haploid filamentation but largely dispensable for mating and virulence in Cryptococcus neoformans.

    Changli Yue;L. M. Cavallo;J. A. Alspaugh;Ping Wang

  • pH Response Pathways in Fungi: Adapting to Host-derived and Environmental Signals.

    Kyla Selvig;J. Andrew Alspaugh

  • Ras1 and Ras2 contribute shared and unique roles in physiology and virulence of Cryptococcus neoformans.

    Michael S Waugh;Michael S Waugh;Connie B Nichols;Connie B Nichols;Cameron M DeCesare;Gary M Cox

  • Virulence mechanisms and Cryptococcus neoformans pathogenesis.

    J. Andrew Alspaugh

  • Cryptococcus neoformans Rim101 Is Associated with Cell Wall Remodeling and Evasion of the Host Immune Responses

    Teresa R. O'Meara;Stephanie M. Holmer;Kyla Selvig;Fred Dietrich

  • Cryptococcal Titan Cell Formation Is Regulated by G-Protein Signaling in Response to Multiple Stimuli

    Laura H. Okagaki;Yina Wang;Elizabeth R. Ballou;Teresa R. O'Meara

  • Signal transduction pathways regulating differentiation and pathogenicity of Cryptococcus neoformans.

    J.Andrew Alspaugh;John R. Perfect;Joseph Heitman

  • The Cryptococcus neoformans Catalase Gene Family and Its Role in Antioxidant Defense

    Steven S. Giles;Jason E. Stajich;Connie Nichols;Quincy D. Gerrald

  • A Ras1-Cdc24 signal transduction pathway mediates thermotolerance in the fungal pathogen Cryptococcus neoformans.

    Connie B. Nichols;Zahra H. Perfect;J. Andrew Alspaugh

  • Transcription factor Nrg1 mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans.

    Kari L. Cramer;Quincy D. Gerrald;Connie B. Nichols;Michael S. Price

  • Role of Protein O-Mannosyltransferase Pmt4 in the Morphogenesis and Virulence of Cryptococcus neoformans

    Gillian M. Olson;Deborah S. Fox;Ping Wang;J. Andrew Alspaugh

Frequent Co-Authors

Joseph Heitman
Joseph Heitman Duke University
John R. Perfect
John R. Perfect Duke University
Gerald F. Bills
Gerald F. Bills The University of Texas Health Science Center at Houston
Gary M. Cox
Gary M. Cox Duke University
James B. Gloer
James B. Gloer University of Iowa
Fred S. Dietrich
Fred S. Dietrich Duke University
Sue Jinks-Robertson
Sue Jinks-Robertson Duke University
Maria Sueli Soares Felipe
Maria Sueli Soares Felipe Universidade Católica de Brasília
Carol A. Munro
Carol A. Munro University of Aberdeen
Jason E. Stajich
Jason E. Stajich University of California, Riverside

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