James A. Fraser

Overview

Best Publications

• MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

  Rebecca C. Coll;James R. Hill;Christopher J. Day;Alina Zamoshnikova

  932
  Citations

• The Genome of the Basidiomycetous Yeast and Human Pathogen Cryptococcus Neoformans

  Brendan J. Loftus;Eula Fung;Paola Roncaglia;Don Rowley

  882
  Citations

• Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis

  Kyung J. Kwon-Chung;James A. Fraser;Tamara L. Doering;Zhuo A. Wang

  598
  Citations

• Deciphering the model pathogenic fungus Cryptococcus neoformans.

  Alexander Idnurm;Yong Sun Bahn;Kirsten Nielsen;Xiaorong Lin

  458
  Citations

• Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence Attenuation

  Guilhem Janbon;Kate L. Ormerod;Damien Paulet;Edmond J. Byrnes

  433
  Citations

• Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: implications for an outbreak on Vancouver Island, Canada

  James A. Fraser;Ryan L. Subaran;Connie B. Nichols;Joseph Heitman

  412
  Citations

• Mating-Type Locus of Cryptococcus neoformans: a Step in the Evolution of Sex Chromosomes

  Klaus B. Lengeler;Deborah S. Fox;James A. Fraser;Andria Allen

  361
  Citations

• Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms.

  James A Fraser;Stephanie Diezmann;Ryan L Subaran;Andria Allen

  269
  Citations

• Genome Variation in Cryptococcus gattii, an Emerging Pathogen of Immunocompetent Hosts

  C. A. D’Souza;J. W. Kronstad;G. Taylor;R. Warren

  240
  Citations

• Evolution of fungal sex chromosomes.

  James A. Fraser;Joseph Heitman

  180
  Citations

• Polyploid Titan Cells Produce Haploid and Aneuploid Progeny To Promote Stress Adaptation

  Aleeza C. Gerstein;Man Shun Fu;Liliane Mukaremera;Zhongming Li

  167
  Citations

• Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators

  Benjamin Hommel;Benjamin Hommel;Benjamin Hommel;Liliane Mukaremera;Radames J.B. Cordero;Carolina Coelho

  145
  Citations

• Recent Evolution of the Human Pathogen Cryptococcus neoformans by Intervarietal Transfer of a 14-Gene Fragment

  Laura A. Kavanaugh;James A. Fraser;Fred S. Dietrich

  144
  Citations

• Whole Genome Comparison Reveals High Levels of Inbreeding and Strain Redundancy Across the Spectrum of Commercial Wine Strains of Saccharomyces cerevisiae

  Anthony R. Borneman;Anthony R. Borneman;Angus H. Forgan;Radka Kolouchova;James A. Fraser

  142
  Citations

• Importance of resolving fungal nomenclature: The case of multiple pathogenic species in the Cryptococcus genus

  Ferry Hagen;H. Thorsten Lumbsch;Valentina Arsic Arsenijevic;Hamid Badali

  136
  Citations

• Chromosomal sex-determining regions in animals, plants and fungi

  James A Fraser;Joseph Heitman

  132
  Citations

• Evolution of the Mating Type Locus: Insights Gained from the Dimorphic Primary Fungal Pathogens Histoplasma capsulatum, Coccidioides immitis, and Coccidioides posadasii

  James A. Fraser;Jason E. Stajich;Eric J. Tarcha;Garry T. Cole

  130
  Citations

• A diverse population of Cryptococcus gattii molecular type VGIII in southern Californian HIV/AIDS patients.

  Edmond J. Byrnes;Wenjun Li;Ping Ren;Yonathan Lewit

  130
  Citations

• PAK kinases Ste20 and Pak1 govern cell polarity at different stages of mating in Cryptococcus neoformans.

  Connie B. Nichols;James A. Fraser;Joseph Heitman

  119
  Citations

• Nuclear accumulation of the GATA factor AreA in response to complete nitrogen starvation by regulation of nuclear export.

  Richard B. Todd;James A. Fraser;Koon Ho Wong;Meryl A. Davis

  114
  Citations