2018 - Australian Laureate Fellow
His primary scientific interests are in Biochemistry, Protein structure, Leucine-rich repeat, Nuclear transport and Nuclear localization sequence. As part of his studies on Biochemistry, Bostjan Kobe often connects relevant areas like Biophysics. His Protein structure study which covers NLR Proteins that intersects with Receptor complex and Arabidopsis.
His research in Leucine-rich repeat intersects with topics in Sequence motif, Nucleic acid, Ribonuclease inhibitor and Plasma protein binding. His studies in Ribonuclease inhibitor integrate themes in fields like Pancreatic ribonuclease, Pentapeptide repeat and In vivo. His Nuclear transport study combines topics from a wide range of disciplines, such as Nuclear protein, Computational biology and NLS.
Bostjan Kobe spends much of his time researching Biochemistry, Cell biology, Protein structure, Computational biology and Crystallography. His Biochemistry study frequently draws parallels with other fields, such as Biophysics. His study focuses on the intersection of Protein structure and fields such as Leucine-rich repeat with connections in the field of Ribonuclease inhibitor.
His Crystallography research is multidisciplinary, incorporating elements of Crystallization and Protein–protein interaction. His studies examine the connections between Kinase and genetics, as well as such issues in Phosphorylation, with regards to Peptide sequence. Bostjan Kobe combines subjects such as Genetics and Function with his study of Effector.
His scientific interests lie mostly in Cell biology, Crystal structure, Innate immune system, Crystallography and Effector. His studies deal with areas such as Mutagenesis, Receptor, In vitro and NAD+ kinase as well as Cell biology. His Crystal structure research incorporates elements of Biophysics, Mutant, Drosophila and Stereochemistry.
His Crystallography study integrates concerns from other disciplines, such as Plant disease resistance, Mutagenesis, Tris, Glycerol and Ribose. Bostjan Kobe has included themes like Immune receptor, Transgene, Secretion, Arabidopsis and Function in his Effector study. Protein structure is a subfield of Biochemistry that Bostjan Kobe studies.
His primary areas of study are Cell biology, Effector, Innate immune system, Receptor and Inflammasome. His work is dedicated to discovering how Cell biology, NAD+ kinase are connected with Allosteric regulation and Axon and other disciplines. His Effector research integrates issues from Immune receptor, Transgene, Extracellular, Protein domain and Arabidopsis.
His Arabidopsis study is associated with Genetics. His Innate immune system research is multidisciplinary, relying on both Signal transduction, Computational biology and Function. His biological study spans a wide range of topics, including Antigen and Glycan.
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The leucine-rich repeat as a protein recognition motif
Bostjan Kobe;Andrey V Kajava.
Current Opinion in Structural Biology (2001)
The leucine-rich repeat: a versatile binding motif.
Bostjan Kobe;Johann Deisenhofer.
Trends in Biochemical Sciences (1994)
A structural basis of the interactions between leucine-rich repeats and protein ligands.
Bostjan Kobe;Bostjan Kobe;Bostjan Kobe;Johann Deisenhofer.
Nature (1995)
Direct protein interaction underlies gene-for-gene specificity and coevolution of the flax resistance genes and flax rust avirulence genes
Peter N. Dodds;Gregory J. Lawrence;Ann-Maree Catanzariti;Trazel Teh.
Proceedings of the National Academy of Sciences of the United States of America (2006)
Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats
Bostjan Kobe;Johann Deisenhofer.
Nature (1993)
Uses for JNK: the Many and Varied Substrates of the c-Jun N-Terminal Kinases
Marie A. Bogoyevitch;Bostjan Kobe.
Microbiology and Molecular Biology Reviews (2006)
Proteins with leucine-rich repeats
Bostjan Kobe;Johann Deisenhofer.
Current Opinion in Structural Biology (1995)
Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin alpha.
Bostjan Kobe.
Nature Structural & Molecular Biology (1999)
Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha
Marcos R.M. Fontes;Trazel Teh;Bostjan Kobe.
Journal of Molecular Biology (2000)
Molecular basis for specificity of nuclear import and prediction of nuclear localization
Mary Marfori;Andrew Mynott;Jonathan J. Ellis;Ahmed M. Mehdi.
Biochimica et Biophysica Acta (2011)
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