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Athan Kuliopulos

Athan Kuliopulos

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
10976
World Ranking
13287
National Ranking
5654

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Athan Kuliopulos is a researcher affiliated with Tufts University in the United States. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with particular focus on Molecular Biology, Surgery, Cardiology and Cardiovascular Medicine, Hematology, and Infectious Diseases.

The research conducted by Athan Kuliopulos covers several main topics including Blood Coagulation and Thrombosis Mechanisms, Liver Disease Diagnosis and Treatment, Diet, Metabolism, and Disease, Receptor Mechanisms and Signaling, Neuropeptides and Animal Physiology, Pancreatic Function and Diabetes, and Acute Myocardial Infarction Research.

Recent publications authored or co-authored by Kuliopulos include:

  • PAR2 promotes impaired glucose uptake and insulin resistance in NAFLD through GLUT2 and Akt interference, 2022, Hepatology
  • PAR1 (Protease-Activated Receptor 1) Pepducin Therapy Targeting Myocardial Necrosis in Coronary Artery Disease and Acute Coronary Syndrome Patients Undergoing Cardiac Catheterization, 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • Lipid Receptor GPR31 (G-Protein-Coupled Receptor 31) Regulates Platelet Reactivity and Thrombosis Without Affecting Hemostasis, 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • Lipopeptide Pepducins as Therapeutic Agents, 2021, Methods in Molecular Biology
  • Deficiency of MMP1a (Matrix Metalloprotease 1a) Collagenase Suppresses Development of Atherosclerosis in Mice, 2021, Arteriosclerosis Thrombosis and Vascular Biology

Kuliopulos frequently collaborates with several researchers, most notably Lidija Covic, Elizabeth K. Fletcher, Paul A. Gurbel, Susan E. Turner, and Kevin P. Bliden.

The scientist's work is often published in venues such as Arteriosclerosis Thrombosis and Vascular Biology, Hepatology, Methods in Molecular Biology, Circulation Heart Failure, and the Journal of the American College of Cardiology.

Athan Kuliopulos is recognized as a Member of the Association of American Physicians.

Best Publications

  • PAR1 Is a Matrix Metalloprotease-1 Receptor that Promotes Invasion and Tumorigenesis of Breast Cancer Cells

    Adrienne Boire;Adrienne Boire;Lidija Covic;Anika Agarwal;Suzanne Jacques

  • Activation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptides

    Lidija Covic;Amy L. Gresser;Joyce Talavera;Steven Swift

  • Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation.

    Lidija Covic;Meghna Misra;Jehangir Badar;Christopher Singh

  • Protease-Activated Receptors in Cardiovascular Diseases

    Andrew J. Leger;Lidija Covic;Athan Kuliopulos

  • Biphasic kinetics of activation and signaling for PAR1 and PAR4 thrombin receptors in platelets.

    Lidija Covic;and Amy L. Gresser;Athan Kuliopulos

  • Disruption of the Mouse μ-Calpain Gene Reveals an Essential Role in Platelet Function

    Mohammad Azam;Shaida S. Andrabi;Kenneth E. Sahr;Lakshmi Kamath

  • Blocking the Protease-Activated Receptor 1-4 Heterodimer in Platelet-Mediated Thrombosis

    Andrew J. Leger;Suzanne L. Jacques;Jehangir Badar;Nicole C. Kaneider

  • Platelet Matrix Metalloprotease-1 Mediates Thrombogenesis by Activating PAR1 at a Cryptic Ligand Site

    Vishal Trivedi;Adrienne Boire;Boris Tchernychev;Nicole C. Kaneider

  • 'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage

    Nicole C Kaneider;Andrew J Leger;Anika Agarwal;Nga Nguyen

  • Plasmin desensitization of the PAR1 thrombin receptor: kinetics, sites of truncation, and implications for thrombolytic therapy

    Athan Kuliopulos;Lidija Covic;Stacy K. Seeley;Paul J. Sheridan

  • Matrix metalloproteases and PAR1 activation.

    Karyn M. Austin;Lidija Covic;Athan Kuliopulos

  • Turning Receptors On and Off with Intracellular Pepducins: New Insights into G-protein-coupled Receptor Drug Development

    Katie O'Callaghan;Athan Kuliopulos;Lidija Covic

  • Quantitative interpretations of double mutations of enzymes

    Albert S. Mildvan;David J. Weber;Athan Kuliopulos

  • Signaling from protease-activated receptor-1 inhibits migration and invasion of breast cancer cells

    Lakshmi Kamath;Ahou Meydani;Francine Foss;Athan Kuliopulos

  • Reversing systemic inflammatory response syndrome with chemokine receptor pepducins

    Nicole C Kaneider;Anika Agarwal;Andrew J Leger;Athan Kuliopulos

  • Production, Purification, and Cleavage of Tandem Repeats of Recombinant Peptides

    Athan Kuliopulos;Christopher T. Walsh

  • Kinetic and ultraviolet spectroscopic studies of active-site mutants of delta 5-3-ketosteroid isomerase.

    Athan Kuliopulos;Albert S. Mildvan;David Shortle;Paul Talalay

  • Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis.

    Eric Yang;Adrienne Boire;Anika Agarwal;Nga Nguyen

  • Interdicting protease-activated receptor-2-driven inflammation with cell-penetrating pepducins

    Leila M. Sevigny;Ping Zhang;Andrew Bohm;Katherine Lazarides

  • Identification of a Metalloprotease-Chemokine Signaling System in the Ovarian Cancer Microenvironment: Implications for Antiangiogenic Therapy

    Anika Agarwal;Sarah L. Tressel;Rajani Kaimal;Marianthi Balla

Frequent Co-Authors

Paul A. Gurbel
Paul A. Gurbel Inova Fairfax Hospital
Christopher T. Walsh
Christopher T. Walsh Stanford University
Bruce Furie
Bruce Furie Beth Israel Deaconess Medical Center
Albert S. Mildvan
Albert S. Mildvan Johns Hopkins University
Barbara C. Furie
Barbara C. Furie Tufts University
Udaya S. Tantry
Udaya S. Tantry Johns Hopkins University
Sarah L. Booth
Sarah L. Booth Tufts University
Philip W. Hinds
Philip W. Hinds Tufts University
David M. Roth
David M. Roth University of California San Diego
Thomas P. Sakmar
Thomas P. Sakmar Rockefeller University

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