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D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
9824
World Ranking
13398
National Ranking
5694

Overview

JoAnn Trejo is affiliated with the University of California, San Diego in the United States. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, with a significant focus on Medicine. Within these broader fields, their work concentrates on Molecular Biology, Cell Biology, Hematology, Cancer Research, and Public Health, Environmental and Occupational Health.

The scientist's research topics include:

  • Receptor Mechanisms and Signaling
  • Blood Coagulation and Thrombosis Mechanisms
  • Protease and Inhibitor Mechanisms
  • Protein Kinase Regulation and GTPase Signaling
  • Ubiquitin and proteasome pathways
  • Hippo pathway signaling and YAP/TAZ
  • Diversity and Career in Medicine

Publication venues where JoAnn Trejo frequently publishes include:

  • The FASEB Journal
  • UNC Libraries
  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Biology of the Cell

Frequent collaborators in their research activities are Olivia Molinar-Inglis, Dequina Nicholas, Norton Cheng, Helen Wedegaertner, and Cierra A. Birch.

Notable recent publications include:

  • "Post-Translational Modifications of G Protein-Coupled Receptors Control Cellular Signaling Dynamics in Space and Time" (2020) published in Pharmacological Reviews
  • "The burden of service for faculty of color to achieve diversity and inclusion: the minority tax" (2020) published in Molecular Biology of the Cell
  • "Signaling diversity enabled by Rap1-regulated plasma membrane ERK with distinct temporal dynamics" (2020) published in eLife
  • "Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus" (2020) published in Nature Communications
  • "Phosphoproteomic analysis of protease-activated receptor-1 biased signaling reveals unique modulators of endothelial barrier function" (2020) published in Proceedings of the National Academy of Sciences

Best Publications

  • G Protein–Coupled Receptor Sorting to Endosomes and Lysosomes

    Adriano Marchese;May M. Paing;Brenda R.S. Temple;Jo Ann Trejo

  • Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

    Jeffrey L. Brown;Lisa Stowers;Margaret Baer;JoAnn Trejo

  • Signal transduction by protease-activated receptors

    Unice J K Soh;Michael R Dores;Buxin Chen;JoAnn Trejo

  • Clathrin-dependent mechanisms of G protein-coupled receptor endocytosis.

    Breann L. Wolfe;JoAnn Trejo

  • β-Arrestins Regulate Protease-activated Receptor-1 Desensitization but Not Internalization or Down-regulation

    May M. Paing;Amy B. Stutts;Trudy A. Kohout;Robert J. Lefkowitz

  • Protease-activated receptor-2 is essential for factor VIIa and Xa-induced signaling, migration, and invasion of breast cancer cells.

    Dionne R. Morris;Yu Ding;Tiffany K. Ricks;Anuradha Gullapalli

  • The cytoplasmic tails of protease-activated receptor-1 and substance P receptor specify sorting to lysosomes versus recycling.

    JoAnn Trejo;Shaun R. Coughlin;Shaun R. Coughlin

  • Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4.

    Deepali Bhandari;JoAnn Trejo;Jeffrey L. Benovic;Adriano Marchese

  • Role of the Thrombin Receptor's Cytoplasmic Tail in Intracellular Trafficking DISTINCT DETERMINANTS FOR AGONIST-TRIGGERED VERSUS TONIC INTERNALIZATION AND INTRACELLULAR LOCALIZATION

    Michael Jeremy Shapiro;Michael Jeremy Shapiro;JoAnn Trejo;JoAnn Trejo;Dewan Zeng;Dewan Zeng;Shaun R. Coughlin;Shaun R. Coughlin

  • Protease-activated receptor signalling, endocytic sorting and dysregulation in cancer

    Puneeta Arora;Tiffany K Ricks;JoAnn Trejo

  • The Cloned Thrombin Receptor Is Necessary and Sufficient for Activation of Mitogen-activated Protein Kinase and Mitogenesis in Mouse Lung Fibroblasts LOSS OF RESPONSES IN FIBROBLASTS FROM RECEPTOR KNOCKOUT MICE

    JoAnn Trejo;Andrew J. Connolly;Shaun R. Coughlin

  • Activated protein C promotes protease-activated receptor-1 cytoprotective signaling through β-arrestin and dishevelled-2 scaffolds

    Unice J. K. Soh;JoAnn Trejo

  • ALIX binds a YPX3L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting

    Michael R. Dores;Buxin Chen;Huilan Lin;Unice J.K. Soh

  • Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis

    Rowshon Alam;Vidula Dixit;Hyunmin Kang;Zi-bo Li

  • Termination of signaling by protease-activated receptor-1 is linked to lysosomal sorting

    JoAnn Trejo;Stephen R. Hammes;Shaun R. Coughlin

  • Down-regulation of protease-activated receptor-1 is regulated by sorting nexin 1.

    Yingjie Wang;Yixing Zhou;Katalin Szabo;Carol Renfrew Haft

  • PAR-1 contributes to the innate immune response during viral infection

    Silvio Antoniak;A. Phillip Owens;Martin Baunacke;Julie C. Williams

  • Protease-activated receptors: new concepts in regulation of G protein-coupled receptor signaling and trafficking.

    Joann Trejo

  • A role for sorting nexin 2 in epidermal growth factor receptor down-regulation: Evidence for distinct functions of sorting nexin 1 and 2 in protein trafficking

    Anuradha Gullapalli;Tiana A. Garrett;May M. Paing;Courtney T. Griffin

  • Caveolae are required for protease-selective signaling by protease-activated receptor–1

    Angela Russo;Unice J. K. Soh;May M. Paing;Puneeta Arora

Frequent Co-Authors

Shaun R. Coughlin
Shaun R. Coughlin University of California, San Francisco
Jin Zhang
Jin Zhang University of California, San Diego
Tracy M. Handel
Tracy M. Handel University of Montana
Joan Heller Brown
Joan Heller Brown University of California, San Diego
David P. Siderovski
David P. Siderovski West Virginia University
Andre Levchenko
Andre Levchenko Yale University
Thomas W. Smith
Thomas W. Smith University of California, Davis
David Gonzalez
David Gonzalez University of California, San Diego
Kelly S. Doran
Kelly S. Doran University of Colorado Denver
Terry Magnuson
Terry Magnuson University of North Carolina at Chapel Hill

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