What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
Shaun R. Coughlin mainly investigates Thrombin, Cell biology, Biochemistry, Receptor and Platelet.
The various areas that he examines in his Thrombin study include Platelet activation, Signal transduction and Proteases.
His study focuses on the intersection of Biochemistry and fields such as Biophysics with connections in the field of Binding site and Protein structure.
His Receptor study incorporates themes from Gene expression, Cell type and Pharmacology.
The Platelet study combines topics in areas such as Bone marrow and Cathepsin G.
His work deals with themes such as Endocrinology, Coagulation factor II receptor and Thrombomodulin, which intersect with Protease-activated receptor.
His most cited work include:
- Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. (2700 citations)
- Thrombin signalling and protease-activated receptors (1984 citations)
- A dual thrombin receptor system for platelet activation (873 citations)
What are the main themes of his work throughout his whole career to date?
Shaun R. Coughlin mainly focuses on Receptor, Thrombin, Cell biology, Platelet and Thrombin receptor.
His study in Receptor is interdisciplinary in nature, drawing from both Molecular biology, Protease-Activated Receptor 1 and Signal transduction.
His Thrombin research incorporates themes from Platelet activation and Biochemistry.
His Cell biology research also works with subjects such as
- Protease which connect with Proteases,
- Internalization and related Intracellular.
His Platelet research is multidisciplinary, incorporating perspectives in Hemostasis, Endocrinology, Coagulation and Fibrin.
His biological study spans a wide range of topics, including Protease-activated receptor 2, Enzyme-linked receptor and Wild type.
He most often published in these fields:
- Receptor (42.86%)
- Thrombin (41.38%)
- Cell biology (41.87%)
What were the highlights of his more recent work (between 2012-2021)?
- Cell biology (41.87%)
- Immunology (20.69%)
- Receptor (42.86%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Cell biology, Immunology, Receptor, Platelet and Thrombin.
His Cell biology study combines topics from a wide range of disciplines, such as Protease, Green fluorescent protein, Zebrafish, Endothelium and In vivo.
His research in the fields of G protein-coupled receptor overlaps with other disciplines such as S1PR1.
His research in Platelet is mostly focused on Platelet activation.
His primary area of study in Thrombin is in the field of Thrombin receptor.
His research integrates issues of Collagen receptor, Protease-activated receptor and GPVI, Platelet membrane glycoprotein in his study of Thrombin receptor.
Between 2012 and 2021, his most popular works were:
- The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors (423 citations)
- Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2 (208 citations)
- A Rapid Method for Directed Gene Knockout for Screening in G0 Zebrafish (106 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
Shaun R. Coughlin mostly deals with Immunology, Cell biology, G protein-coupled receptor, Platelet and Endothelium.
Shaun R. Coughlin interconnects Thrombosis, Microcirculation and Stem cell in the investigation of issues within Immunology.
Signal transduction and Receptor are the focus of his G protein-coupled receptor studies.
His Receptor research is multidisciplinary, incorporating elements of Transcriptome and Insulin.
His study of Thrombin is a part of Platelet.
His Thrombin receptor study in the realm of Thrombin connects with subjects such as Single-nucleotide polymorphism.
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