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Biology and Biochemistry

D-Index
106
Citations
50378
World Ranking
1138
National Ranking
678

Overview

Shaun R. Coughlin is affiliated with the University of California, San Francisco in the United States. Their research spans multiple fields including Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology. Within these areas, the scientist primarily focuses on subfields such as Cardiology and Cardiovascular Medicine, Immunology and Allergy, Molecular Biology, Neurology, and Cellular and Molecular Neuroscience.

The core topics of Shaun R. Coughlin's work include Atrial Fibrillation Management and Outcomes, Cardiac electrophysiology and arrhythmias, Cardiac Arrhythmias and Treatments, Neuroinflammation and Neurodegeneration Mechanisms, Neuroscience and Neuropharmacology Research, Neural dynamics and brain function, and Dermatology and Skin Diseases.

Recent papers authored or co-authored by Shaun R. Coughlin include the following:

  • Microglial Gi-dependent dynamics regulate brain network hyperexcitability, 2020, Nature Neuroscience
  • Protease-Activated Receptor-2 Regulates Neuro-Epidermal Communication in Atopic Dermatitis, 2020, Frontiers in Immunology
  • Lack of authentic atrial fibrillation in commonly used murine atrial fibrillation models, 2022, PLoS ONE
  • Lack of authentic atrial fibrillation in commonly used murine atrial fibrillation models, 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish, 2020, UNC Libraries

Frequent co-authors in Shaun R. Coughlin's publications include:

  • Fumin Fu
  • Michael Pietropaolo
  • Shilpa Pandit
  • Weiyan Li
  • Oleg Tarnavski

Publication venues where Shaun R. Coughlin has appeared include:

  • Nature Neuroscience
  • Frontiers in Immunology
  • PLoS ONE
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries

Best Publications

  • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation.

    Thien-Khai H. Vu;David T. Hung;Virginia I. Wheaton;Shaun R. Coughlin

  • Thrombin signalling and protease-activated receptors

    Shaun R. Coughlin

  • Protease-activated receptors in hemostasis, thrombosis and vascular biology.

    S. R. Coughlin

  • A dual thrombin receptor system for platelet activation

    Mark L. Kahn;Yao-Wu Zheng;Wei Huang;Violeta Bigornia

  • Monocyte chemoattractant protein-1 in human atheromatous plaques.

    N A Nelken;S R Coughlin;D Gordon;J N Wilcox

  • Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin

    Mark L. Kahn;Mayumi Nakanishi-Matsui;Michael J. Shapiro;Hiroaki Ishihara

  • The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors

    Emma Lefrançais;Guadalupe Ortiz-Muñoz;Axelle Caudrillier;Beñat Mallavia

  • Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails.

    Israel F. Charo;Scott J. Myers;Ann Herman;Christian Franci

  • Protease-activated receptor 3 is a second thrombin receptor in humans.

    Hiroaki Ishihara;Andrew J. Connolly;Dewan Zeng;Mark L. Kahn

  • Promotion of Lymphocyte Egress into Blood and Lymph by Distinct Sources of Sphingosine-1-Phosphate

    Rajita Pappu;Susan R. Schwab;Ivo Cornelissen;João P. Pereira

  • Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa.

    Eric Camerer;Wei Huang;Shaun R. Coughlin

  • How the protease thrombin talks to cells.

    Shaun R. Coughlin

  • Domains specifying thrombin-receptor interaction.

    Thien-Khai H. Vu;Virginia I. Wheaton;David T. Hung;Israel Charo

  • Anatomical Profiling of G Protein-Coupled Receptor Expression

    Jean B. Regard;Isaac T. Sato;Shaun R. Coughlin

  • PAR3 is a cofactor for PAR4 activation by thrombin

    Mayumi Nakanishi-Matsui;Yao-Wu Zheng;David J. Sulciner;Ethan J. Weiss

  • Role of thrombin signalling in platelets in haemostasis and thrombosis

    Gilberto R. Sambrano;Ethan J. Weiss;Yao-Wu Zheng;Wei Huang

  • Role of phosphatidylinositol kinase in PDGF receptor signal transduction

    Shaun R. Coughlin;Jaime A. Escobedo;Lewis T. Williams

  • Role of the thrombin receptor in development and evidence for a second receptor

    Andrew J. Connolly;Hiroaki Ishihara;Mark L. Kahn;Robert V. Farese

  • Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2

    Stephan K. Böhm;Wuyi Kong;Dieter Brömme;Steven P. Smeekens

  • Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates.

    Toshihiko Takeuchi;Jennifer L. Harris;Wei Huang;Kelly W. Yan

Frequent Co-Authors

Mark L. Kahn
Mark L. Kahn University of Pennsylvania
JoAnn Trejo
JoAnn Trejo University of California, San Diego
Lewis T. Williams
Lewis T. Williams University of California, San Francisco
Deborah T. Hung
Deborah T. Hung Harvard University
Israel F. Charo
Israel F. Charo University of California, San Francisco
Jason G. Cyster
Jason G. Cyster University of California, San Francisco
Rodger P. McEver
Rodger P. McEver Oklahoma Medical Research Foundation
Charles S. Craik
Charles S. Craik University of California, San Francisco
Lily Yeh Jan
Lily Yeh Jan University of California, San Francisco
Chad A. Shaw
Chad A. Shaw Baylor College of Medicine

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