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Genetics

D-Index
95
Citations
30825
World Ranking
905
National Ranking
450

Overview

Chad A. Shaw is affiliated with Baylor College of Medicine in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with significant contributions also made in Medicine. The focus areas include Genetics, Molecular Biology, Pulmonary and Respiratory Medicine, Immunology, and Epidemiology.

The scientist's research topics cover a broad range of subjects such as Genomics and Rare Diseases, Genomic variations and chromosomal abnormalities, Congenital heart defects research, Immune responses and vaccinations, Genetic Associations and Epidemiology, Neonatal Respiratory Health Research, and Congenital Diaphragmatic Hernia Studies.

Shaw has published extensively in multiple venues, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • European Journal of Human Genetics
  • Genetics in Medicine
  • UNC Libraries
  • The American Journal of Human Genetics

Some recent papers authored or co-authored by Shaw include:

  • CNVs cause autosomal recessive genetic diseases with or without involvement of SNV/indels (2020, Genetics in Medicine)
  • Low-level parental somatic mosaic SNVs in exomes from a large cohort of trios with diverse suspected Mendelian conditions (2020, Genetics in Medicine)
  • Clinical exome sequencing data reveal high diagnostic yields for congenital diaphragmatic hernia plus (CDH+) and new phenotypic expansions involving CDH (2021, Journal of Medical Genetics)
  • Hematopoietic stem and progenitor cells confer cross-protective trained immunity in mouse models (2023, iScience)
  • Targeted accurate RNA consensus sequencing (tARC-seq) reveals mechanisms of replication error affecting SARS-CoV-2 divergence (2024, Nature Microbiology)

Shaw collaborates frequently with several co-authors, including Pamela N. Luna, Daryl A. Scott, Jill A. Rosenfeld, James R. Lupski, and Bailee Kain, contributing to a number of joint publications across various topics.

Best Publications

  • MeCP2, a key contributor to neurological disease, activates and represses transcription.

    Maria Chahrour;Sung Yun Jung;Chad Shaw;Xiaobo Zhou

  • Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

    Stephan J. Sanders;A. Gulhan Ercan-Sencicek;Vanessa Hus;Rui Luo

  • A Protein–Protein Interaction Network for Human Inherited Ataxias and Disorders of Purkinje Cell Degeneration

    Janghoo Lim;Tong Hao;Chad Shaw;Akash J. Patel

  • Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation.

    Stuart M Chambers;Chad A Shaw;Catherine Gatza;C. Joseph Fisk

  • Resolution of Disease Phenotypes Resulting from Multilocus Genomic Variation

    Jennifer E. Posey;Tamar Harel;Pengfei Liu;Jill A. Rosenfeld

  • High-resolution genomic profiling of chromosomal aberrations using Infinium whole-genome genotyping

    Daniel A. Peiffer;Jennie M. Le;Frank J. Steemers;Weihua Chang

  • Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs

    Eric Londina;Phillipe Lohera;Aristeidis G. Telonis;Kevin Quann

  • A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models

    Xiaomei Zhang;Sofie Claerhout;Aleix Prat;Lacey E. Dobrolecki

  • The spliceosome is a therapeutic vulnerability in MYC-driven cancer

    Tiffany Y.T. Hsu;Lukas M. Simon;Nicholas J. Neill;Richard Marcotte

  • A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.

    Jessica D. Kessler;Kristopher T. Kahle;Kristopher T. Kahle;Tingting Sun;Kristen L. Meerbrey

  • Characterization of Potocki-Lupski syndrome (dup(17)(p11.2p11.2)) and delineation of a dosage-sensitive critical interval that can convey an autism phenotype.

    Lorraine Potocki;Weimin Bi;Diane Treadwell-Deering;Claudia M. B. Carvalho

  • Molecular Signatures of Proliferation and Quiescence in Hematopoietic Stem Cells

    Teresa A Venezia;Akil A Merchant;Akil A Merchant;Carlos A Ramos;Carlos A Ramos;Nathan L Whitehouse

  • Use of Exome Sequencing for Infants in Intensive Care Units: Ascertainment of Severe Single-Gene Disorders and Effect on Medical Management

    Linyan Meng;Linyan Meng;Mohan Pammi;Anirudh Saronwala;Pilar Magoulas;Pilar Magoulas

  • Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression

    Molly S. Bray;Chad A. Shaw;Michael W.S. Moore;Rodrigo A.P. Garcia;Rodrigo A.P. Garcia

  • Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity.

    Srikanth Nagalla;Chad Shaw;Chad Shaw;Xianguo Kong;Altaf A. Kondkar

  • Hematopoietic Fingerprints: an expression database of stem cells and their progeny

    Stuart M. Chambers;Nathan C. Boles;Kuan Yin K. Lin;Megan P. Tierney

  • Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase.

    Tingting Sun;Nicola Aceto;Kristen L. Meerbrey;Jessica D. Kessler

  • Development and validation of a CGH microarray for clinical cytogenetic diagnosis

    Sau W Cheung;Chad A Shaw;Wei Yu;Jiangzham Li

  • MeCP2 binds to non-CG methylated DNA as neurons mature, influencing transcription and the timing of onset for Rett syndrome

    Lin Chen;Kaifu Chen;Laura A. Lavery;Steven Andrew Baker

  • Proinflammatory role for let-7 microRNAS in experimental asthma.

    Sumanth Polikepahad;John M. Knight;Arash O. Naghavi;Toni Oplt

Frequent Co-Authors

James R. Lupski
James R. Lupski Baylor College of Medicine
Arthur L. Beaudet
Arthur L. Beaudet Baylor College of Medicine
Pawel Stankiewicz
Pawel Stankiewicz Baylor College of Medicine
Ankita Patel
Ankita Patel Baylor College of Medicine
Sau Wai Cheung
Sau Wai Cheung Baylor College of Medicine
Carlos A. Bacino
Carlos A. Bacino Baylor College of Medicine
Seema R. Lalani
Seema R. Lalani Baylor College of Medicine
Tomasz Gambin
Tomasz Gambin Warsaw University of Technology
Susan G. Hilsenbeck
Susan G. Hilsenbeck Baylor College of Medicine
John W. Belmont
John W. Belmont Baylor College of Medicine

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