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Ger J. M. Pruijn

Ger J. M. Pruijn

D-Index & Metrics

Molecular Biology

D-Index
75
Citations
18091
World Ranking
1201
National Ranking
33

Overview

Ger J. M. Pruijn is affiliated with Radboud University in the Netherlands and has an extensive publication record in the fields of medicine and biochemistry, genetics, and molecular biology. Their research focuses primarily on molecular biology and immunology, with significant contributions to rheumatology, pulmonary and respiratory medicine, and epidemiology.

The scientist's work spans a diverse range of specialized topics including inflammatory myopathies and dermatomyositis, muscle physiology and disorders, monoclonal and polyclonal antibodies research, RNA modifications and cancer, rheumatoid arthritis research and therapies, immune responses and vaccinations, and T-cell and B-cell immunology.

Their recent papers include the following:

  • BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils, 2020, Cell Reports
  • Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation, 2022, Science Advances
  • Autoantibodies to neutrophil extracellular traps represent a potential serological biomarker in rheumatoid arthritis, 2020, Journal of Autoimmunity
  • Low molecular weight silicones induce cell death in cultured cells, 2020, Scientific Reports
  • 256th ENMC international workshop: Myositis specific and associated autoantibodies (MSA-ab): Amsterdam, The Netherlands, 8-10 October 2021, 2022, Neuromuscular Disorders

Frequent co-authors who have contributed to multiple joint publications with Ger J. M. Pruijn include:

  • Leo A. B. Joosten (5 publications)
  • Baziel G.M. van Engelen (5 publications)
  • Olivier Benvéniste (4 publications)
  • Anna Greco (4 publications)
  • Rogier M. Thurlings (3 publications)

Key publication venues for their research include:

  • Annals of the Rheumatic Diseases (4 publications)
  • Journal of Neuromuscular Diseases (3 publications)
  • Journal of Autoimmunity (2 publications)
  • Cell Reports (1 publication)
  • Science Advances (1 publication)

The scientist's contributions are interdisciplinary, integrating immunological and molecular biological approaches to understand inflammatory and autoimmune diseases, particularly focusing on mechanisms underlying muscle disorders and rheumatoid arthritis.

Best Publications

  • AU binding proteins recruit the exosome to degrade ARE-containing mRNAs.

    Ching Yi Chen;Roberto Gherzi;Shao En Ong;Edward L. Chan

  • PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease.

    Erik R. Vossenaar;Albert J.W. Zendman;Walther J. van Venrooij;Ger J.M. Pruijn

  • Autoantigen microarrays for multiplex characterization of autoantibody responses

    William H. Robinson;Carla DiGennaro;Wolfgang Hueber;Brian B. Haab

  • Mutations in the RNA Component of RNase MRP Cause a Pleiotropic Human Disease, Cartilage-Hair Hypoplasia

    Maaret Ridanpää;Hans van Eenennaam;Katarina Pelin;Robert Chadwick

  • The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements.

    Devi Mukherjee;Min Gao;J.Patrick O'Connor;Reinout Raijmakers

  • Anti-CCP antibodies: the past, the present and the future.

    Walther J. van Venrooij;Joyce J. B. C. van Beers;Ger J. M. Pruijn

  • Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis

    Diane van der Woude;Solbritt Rantapää-Dahlqvist;Andreea Ioan-Facsinay;Carla Onnekink

  • NETosis, complement, and coagulation: a triangular relationship.

    Cynthia M de Bont;Wilbert C Boelens;Ger J M Pruijn

  • Preventing thiol-yne addition improves the specificity of strain-promoted azide-alkyne cycloaddition

    Remon van Geel;Ger J M Pruijn;Floris L van Delft;Wilbert C Boelens

  • Citrullination: a small change for a protein with great consequences for rheumatoid arthritis.

    Walther J van Venrooij;Ger J M Pruijn

  • Nuclear factor III, a novel sequence-specific DNA-binding protein from HeLa cells stimulating adenovirus DNA replication.

    Ger J. M. Pruijn;Wim van Driel;Peter C. van der Vliet

  • BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils

    Simone J.C.F.M. Moorlag;Yessica Alina Rodriguez-Rosales;Joshua Gillard;Stephanie Fanucchi

  • Autoantibodies to cytosolic 5'-nucleotidase 1A in inclusion body myositis

    Helma Pluk;Bas J. A. van Hoeve;Sander H. J. van Dooren;Judith Stammen-Vogelzangs

  • Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility

    Dewi Astuti;Mark R Morris;Mark R Morris;Wendy N Cooper;Raymond H J Staals

  • Anti-CCP Antibody, a Marker for the Early Detection of Rheumatoid Arthritis.

    Walther J. Van Venrooij;Joyce J.B.C. Van Beers;Ger J.M. Pruijn

  • Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis

    Yoann Rombouts;Annemiek Willemze;Joyce J B C van Beers;Jing Shi

  • Human La Antigen Is Required for the Hepatitis C Virus Internal Ribosome Entry Site-mediated Translation

    Naushad Ali;Ger J.M. Pruijn;Daniel James Kenan;Jack D. Keene

  • The extent of the anti-citrullinated protein antibody repertoire is associated with arthritis development in patients with seropositive arthralgia

    Lotte A van de Stadt;Ann R van der Horst;Margret H M T de Koning;Wouter H Bos

  • Periodontal Pathogens Directly Promote Autoimmune Experimental Arthritis by Inducing a TLR2- and IL-1–Driven Th17 Response

    Sabrina Garcia de Aquino;Shahla Abdollahi-Roodsaz;Marije I. Koenders;Fons A. J. van de Loo

  • Use and significance of anti-CCP autoantibodies in rheumatoid arthritis

    A.J.W. Zendman;W.J.W. van Venrooij;G.J.M. Pruijn

Frequent Co-Authors

Wilbert C. Boelens
Wilbert C. Boelens Radboud University
W. J. Van Venrooij
W. J. Van Venrooij Radboud University
Jan W. Drijfhout
Jan W. Drijfhout Leiden University Medical Center
Ingrid E. Lundberg
Ingrid E. Lundberg Karolinska University Hospital
René E. M. Toes
René E. M. Toes Leiden University Medical Center
Johan Rönnelid
Johan Rönnelid Uppsala University
Janine A. Lamb
Janine A. Lamb University of Manchester
Anca I. Catrina
Anca I. Catrina Karolinska University Hospital
Olivier Benveniste
Olivier Benveniste Sorbonne University
Jan A.M. Smeitink
Jan A.M. Smeitink Radboud University

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